Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexey Kolyada"'
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15345 (2010)
β2GPI is a major antigen for autoantibodies associated with antiphospholipid syndrome (APS), an autoimmune disease characterized by thrombosis and recurrent pregnancy loss. Only the dimeric form of β2GPI generated by anti-β2GPI antibodies is patho
Externí odkaz:
https://doaj.org/article/25381ec303d6492eb29120457a511033
Publikováno v:
FEBS Journal. 282:864-873
β2 glycoprotein I (β2GPI) is the most common antigen for autoimmune antibodies in antiphospholipid syndrome (APS). Thrombosis is a clinical feature of APS. We created a molecule (A1-A1) that consists of two identical β2GPI-binding modules from Apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bde132413a755e46fbe376c292a0662
https://doi.org/10.1111/febs.13185
https://doi.org/10.1111/febs.13185
Publikováno v:
Antibodies; Volume 6; Issue 2; Pages: 8
Antibodies (Basel, Switzerland)
Antibodies (Basel, Switzerland)
Upregulation of the procoagulant activity of monocytes by antibodies to beta2- glycoprotein I (β2GPI) is one of the mechanisms contributing to thrombosis in antiphospholipid syndrome. Current knowledge about receptors responsible for the upregulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a2b1476ee1d0c9e7809fabe7960bef
Publikováno v:
Blood. 123:1090-1097
Antiphospholipid syndrome (APS) is an autoimmune disorder with increased risk for thrombosis and pregnancy losses. β2-glycoprotein I (β2GPI) is the major antigen for clinically relevant antibodies in APS. We engineered a molecule, A1-A1, which inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1538a350f674ab7ed5b0542fc461357
https://doi.org/10.1182/blood-2013-08-520882
https://doi.org/10.1182/blood-2013-08-520882
Autor:
Ioannis Karageorgos, Alexey Kolyada, Qingen Ke, Pardeep Mahlawat, David A. Barrios, Peter M. Kang, Natalia Beglova
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 14(6)
UNLABELLED Essentials (NZWxBXSB)F1 male mice develop antibodies beta2-glycoprotein I (β2GPI) and hypertension. A1-A1 is a soluble analogue of ApoE receptor 2 with a high affinity for β2GPI/antibody complexes. A1-A1 improved blood pressure and arter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0986edf3f2d7af46b149ebb171ecae0f
https://pubmed.ncbi.nlm.nih.gov/26990752
https://pubmed.ncbi.nlm.nih.gov/26990752
Antiphospholipid syndrome (APS) is an autoimmune disease with clinical manifestations of thrombosis and pregnancy complications. Beta2-glycoprotein I (β2GPI) is the major antigen for the APS-related antibodies. Heparin, low-molecular weight heparin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4309dbc83f3f40ae7373cc1a4b0209a1
https://europepmc.org/articles/PMC3775933/
https://europepmc.org/articles/PMC3775933/
Publikováno v:
Blood. 122:1099-1099
B2GPI is the major antigen for pathogenic antibodies in antiphospholipid syndrome (APS). The presence of anti-b2GPI antibodies correlates with increased risk for thrombosis and pregnancy loss in patients with APS. In animal models of thrombosis, anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbddbb666580055a910d1eb07053cdc4
https://doi.org/10.1182/blood.v122.21.1099.1099
https://doi.org/10.1182/blood.v122.21.1099.1099
Publikováno v:
Blood. 118:1209-1209
Abstract 1209 Background: The presence of autoimmune antibodies directed to beta2-glycoprotein-I (B2GPI) often leads to thrombosis in antiphospholipid syndrome (APS). Heparin, low molecular weight heparin (LMWH) and fondaparinux are commonly used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de22819604f3c21e6c1ea758cc8b8732
https://doi.org/10.1182/blood.v118.21.1209.1209
https://doi.org/10.1182/blood.v118.21.1209.1209
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15345 (2010)
PLoS ONE
PLoS ONE
{beta}2GPI is a major antigen for autoantibodies associated with antiphospholipid syndrome (APS), an autoimmune disease characterized by thrombosis and recurrent pregnancy loss. Only the dimeric form of {beta}2GPI generated by anti-{beta}2GPI antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e496a0d3198ead36645ddf78952ef5d
https://doi.org/10.1371/journal.pone.0015345
https://doi.org/10.1371/journal.pone.0015345
Publikováno v:
Blood. 116:1142-1142
Abstract 1142 ß2GPI is a major antigen for autoantibodies associated with antiphospholipid syndrome, an autoimmune disease characterized by thrombosis and recurrent pregnancy loss. Only the dimeric form of ß2GPI generated by anti-ß2GPI antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c09874e8924f5cabe2b31e3ee9d6c52
https://doi.org/10.1182/blood.v116.21.1142.1142
https://doi.org/10.1182/blood.v116.21.1142.1142