Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexey Kh Baimiev"'
Autor:
Yan A. Ivanenkov, Alex Zhavoronkov, Renat S. Yamidanov, Ilya A. Osterman, Petr V. Sergiev, Vladimir A. Aladinskiy, Anastasia V. Aladinskaya, Victor A. Terentiev, Mark S. Veselov, Andrey A. Ayginin, Victor G. Kartsev, Dmitry A. Skvortsov, Alexey V. Chemeris, Alexey Kh. Baimiev, Alina A. Sofronova, Alexander S. Malyshev, Gleb I. Filkov, Dmitry S. Bezrukov, Bogdan A. Zagribelnyy, Evgeny O. Putin, Maria M. Puchinina, Olga A. Dontsova
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Many pharmaceutical companies are avoiding the development of novel antibacterials due to a range of rational reasons and the high risk of failure. However, there is an urgent need for novel antibiotics especially against resistant bacterial strains.
Externí odkaz:
https://doaj.org/article/8c16a1d4d0ea467faf6fd76819573bdc
Autor:
Vladimir A. Aladinskiy, Rostislav A Petrov, Yan A. Ivanenkov, Mark S. Veselov, Andrey A Ayginin, Alexey Kh Baimiev, Maria M Puchinina, Marina A Maximova, Anastasia V. Aladinskaya, Dmitry A. Skvortsov, Kseniya Yu Shvetc, Yulia V. Vakhitova, Alina A. Sofronova, Ilya A. Osterman, Andrey Kh Baimiev, Zulfiya R Zileeva, Katerina S Komarova, Dmitry S. Bezrukov, L. F. Zainullina, Victor A Terentiev, Bogdan A Zagribelnyy, Petr V. Sergiev, Alexey E. Machulkin, Renat S. Yamidanov, Olga A. Dontsova
Publikováno v:
Current Drug Discovery Technologies. 17:716-724
Background: The key issue in the development of novel antimicrobials is a rapid expansion of new bacterial strains resistant to current antibiotics. Indeed, World Health Organization has reported that bacteria commonly causing infections in hospitals
Autor:
Rostislav A Petrov, Dmitry A. Skvortsov, Yulia V. Vakhitova, L. F. Zainullina, Andrey A Ayginin, Yan A. Ivanenkov, Marina A Maximova, Mark S. Veselov, Alina A. Sofronova, Petr V. Sergiev, G. I. Filkov, Alexey E. Machulkin, Katerina S Komarova, Anastasia V. Aladinskaya, Renat S. Yamidanov, Victor A Terentiev, Olga A. Dontsova, Alexander S. Malyshev, Alexey Kh Baimiev, Maria M Puchinina, Ilya A. Osterman, Dmitry S. Bezrukov, A. V. Chemeris, Zulfiya R Zileeva, Vladimir A. Aladinskiy
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 22:346-354
Aim and Objective:Antibiotic resistance is a serious constraint to the development of new effective antibacterials. Therefore, the discovery of the new antibacterials remains one of the main challenges in modern medicinal chemistry. This study was un
Autor:
Rostislav A Petrov, Marina A Maximova, Yan A. Ivanenkov, Andrey A Ayginin, Zulfiya R Zileeva, Ilya A. Osterman, Dmitry S. Bezrukov, Alexey E. Machulkin, Katerina S Komarova, Victor A Terentiev, Mark S. Veselov, Vladimir A. Aladinskiy, Olga A. Dontsova, Anastasia V. Aladinskaya, Dmitry A. Skvortsov, Yulia V. Vakhitova, Renat S. Yamidanov, Alina A. Sofronova, Petr V. Sergiev, A. V. Chemeris, G. I. Filkov, Svetlana Yu. Maklakova, L. F. Zainullina, Victor G Kartsev, Alexey Kh Baimiev
Publikováno v:
Molecular diversity. 24(1)
A series of 5-oxo-4H-pyrrolo[3,2-b]pyridine derivatives was identified as novel class of highly potent antibacterial agents during an extensive large-scale high-throughput screening (HTS) program utilizing a unique double-reporter system—pDualrep2.