Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Alexey E. Tupikin"'
Autor:
Yueming Tian, Elena S. Babaylova, Alexander V. Gopanenko, Alexey E. Tupikin, Marsel R. Kabilov, Alexey A. Malygin
Publikováno v:
Open Biology, Vol 14, Iss 1 (2024)
Ribosomal protein uS10, a product of the RPS20 gene, is an essential constituent of the small (40S) subunit of the human ribosome. Disruptive mutations in its gene are associated with a predisposition to hereditary colorectal carcinoma. Here, using H
Externí odkaz:
https://doaj.org/article/224cea2db7774606aa9a223cad50c553
Autor:
Olga G. Kurskaya, Elena A. Prokopyeva, Nikita A. Dubovitskiy, Mariya V. Solomatina, Ivan A. Sobolev, Anastasiya A. Derko, Alina R. Nokhova, Angelika V. Anoshina, Natalya V. Leonova, Olga A. Simkina, Tatyana V. Komissarova, Alexey E. Tupikin, Marsel R. Kabilov, Alexander M. Shestopalov, Kirill A. Sharshov
Publikováno v:
Viruses, Vol 16, Iss 3, p 386 (2024)
The human adenovirus (HAdV) is a common pathogen in children that can cause acute respiratory virus infection (ARVI). However, the molecular epidemiological and clinical information relating to HAdV among hospitalized children with ARVI is rarely rep
Externí odkaz:
https://doaj.org/article/a56a6f03eda34510921b6a4705e9b00f
Autor:
Yakov A. Lomakin, Ivan V. Zvyagin, Leyla A. Ovchinnikova, Marsel R. Kabilov, Dmitriy B. Staroverov, Artem Mikelov, Alexey E. Tupikin, Maria Y. Zakharova, Nadezda A. Bykova, Vera S. Mukhina, Alexander V. Favorov, Maria Ivanova, Taras Simaniv, Yury P. Rubtsov, Dmitriy M. Chudakov, Maria N. Zakharova, Sergey N. Illarioshkin, Alexey A. Belogurov, Alexander G. Gabibov
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundB lymphocytes play a pivotal regulatory role in the development of the immune response. It was previously shown that deficiency in B regulatory cells (Bregs) or a decrease in their anti-inflammatory activity can lead to immunological dysfun
Externí odkaz:
https://doaj.org/article/d528caab928e4513a84bb21ec05cf1a7
Autor:
Elizaveta A. Zolotenkova, Alexander V. Gopanenko, Alexey E. Tupikin, Marsel R. Kabilov, Alexey A. Malygin
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6173 (2023)
Ribosomal protein uL15 (RPL27a) carries a specific modification, hydroxylation, at the His39 residue, which neighbors the CCA terminus of the E-site-bound tRNA at the mammalian ribosome. Under hypoxia, the level of hydroxylation of this protein decre
Externí odkaz:
https://doaj.org/article/b1f97c58377f4d21b7c4ae1c53d3e0ba
Autor:
Nadezhda S. Dyrkheeva, Anastasia A. Malakhova, Aleksandra L. Zakharenko, Larisa S. Okorokova, Dmitriy N. Shtokalo, Sophia V. Pavlova, Sergey P. Medvedev, Suren M. Zakian, Anna A. Nushtaeva, Alexey E. Tupikin, Marsel R. Kabilov, Svetlana N. Khodyreva, Olga A. Luzina, Nariman F. Salakhutdinov, Olga I. Lavrik
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5148 (2023)
Topoisomerase 1 (TOP1) is an enzyme that regulates DNA topology and is essential for replication, recombination, and other processes. The normal TOP1 catalytic cycle involves the formation of a short-lived covalent complex with the 3′ end of DNA (T
Externí odkaz:
https://doaj.org/article/ed3c358c6ece453bb1250e334bb40dbb
Autor:
Svetlana A. Romanenko, Dmitry Yu. Prokopov, Anastasia A. Proskuryakova, Guzel I. Davletshina, Alexey E. Tupikin, Fumio Kasai, Malcolm A. Ferguson-Smith, Vladimir A. Trifonov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13063 (2022)
Tandemly arranged and dispersed repetitive DNA sequences are important structural and functional elements that make up a significant portion of vertebrate genomes. Using high throughput, low coverage whole genome sequencing followed by bioinformatics
Externí odkaz:
https://doaj.org/article/ab0d3821c1034ee18f804b274c06fa24
Autor:
Ekaterina S. Komarova, Anna N. Slesarchuk, Maria P. Rubtsova, Ilya A. Osterman, Alexey E. Tupikin, Dmitry V. Pyshnyi, Olga A. Dontsova, Marsel R. Kabilov, Petr V. Sergiev
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12293 (2022)
Flow-seq is a method that combines fluorescently activated cell sorting and next-generation sequencing to deduce a large amount of data about translation efficiency from a single experiment. Here, we constructed a library of fluorescent protein-based
Externí odkaz:
https://doaj.org/article/f532417df82c4396b132a555844fd512
Autor:
Olga A. Kossinova, Alexander V. Gopanenko, Elena S. Babaylova, Alexey E. Tupikin, Marsel R. Kabilov, Alexey A. Malygin, Galina G. Karpova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9740 (2022)
The RNA cytosine C5 methyltransferase NSUN2 has a variety of RNA substrates and plays an important role in mRNA metabolism. NSUN2 binds to specific sequences enriched in exosomal mRNAs, suggesting its possible involvement in the sorting of mRNAs into
Externí odkaz:
https://doaj.org/article/8a73f0d5d4e84d8587f22adb68813492
Autor:
Yueming Tian, Elena S. Babaylova, Alexander V. Gopanenko, Alexey E. Tupikin, Marsel R. Kabilov, Alexey A. Malygin, Galina G. Karpova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6174 (2022)
A number of mutations in the RPS20 gene encoding the ribosomal protein uS10 have been found to be associated with a predisposition to hereditary non-polyposis colorectal carcinoma (CRC). We transfected HEK293T cells with constructs carrying the uS10
Externí odkaz:
https://doaj.org/article/392bfc0621494fabb5e85353ec4f1b17
Autor:
Elena S. Babaylova, Alexander V. Gopanenko, Alexey E. Tupikin, Marsel R. Kabilov, Alexey A. Malygin, Galina G. Karpova
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13485 (2021)
Protein uL5 (formerly called L11) is an integral component of the large (60S) subunit of the human ribosome, and its deficiency in cells leads to the impaired biogenesis of 60S subunits. Using RNA interference, we reduced the level of uL5 in HEK293T
Externí odkaz:
https://doaj.org/article/f264d38eb92240f18e20b4751df087b6