Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Alexey B, Mantsyzov"'
Autor:
Igor B. Levshin, Alexander Yu. Simonov, Alexey A. Panov, Natalia E. Grammatikova, Alexander I. Alexandrov, Eslam S. M. O. Ghazy, Vasiliy A. Ivlev, Michael O. Agaphonov, Alexey B. Mantsyzov, Vladimir I. Polshakov
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 723 (2024)
A series of hybrid compounds with triazole and thiazolidine nuclei connected by a linker has been synthesized and extensively studied. Various synthetic methods for the target compounds have been tested. A microbiological assessment of the obtained c
Externí odkaz:
https://doaj.org/article/13483073eed24242ad00227215e7d07b
Autor:
Nikita M. Shepelev, Sofia S. Mariasina, Alexey B. Mantsyzov, Alexander N. Malyavko, Sergey V. Efimov, Olga A. Petrova, Elena V. Rodina, Maria I. Zvereva, Olga A. Dontsova, Vladimir I. Polshakov
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Telomerase is a ribonucleoprotein enzyme, which maintains genome integrity in eukaryotes and ensures continuous cellular proliferation. Telomerase holoenzyme from the thermotolerant yeast Hansenula polymorpha, in addition to the catalytic su
Externí odkaz:
https://doaj.org/article/c30a64ef786b423ca96996243d680aa3
Autor:
Alexey B. Mantsyzov, Oleg Y. Savelyev, Polina M. Ivantcova, Stefan Bräse, Konstantin V. Kudryavtsev, Vladimir I. Polshakov
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Synthetic β-peptides are potential functional mimetics of native α-proteins. A recently developed, novel, synthetic approach provides an effective route to the broad group of β-proline oligomers with alternating patterns of stereogenic centers. Co
Externí odkaz:
https://doaj.org/article/d872ab658dee42c6815dcaaa041923a8
Autor:
Vladimir I. Polshakov, Polina M. Ivantcova, Stefan Bräse, Mikhail N. Sokolov, Konstantin V. Kudryavtsev, Alexey B. Mantsyzov
Publikováno v:
The Journal of Organic Chemistry. 85:8865-8871
All possible variants of β-proline functionalized tripeptides consisting of homo/hetero chiral monomeric all-cis 5-arylpyrrolidine-2,4-dicarboxylate units were synthesized for the first time by a n...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6b85035697b5250aa602ac51cee7d80
https://doi.org/10.1021/acs.joc.0c00598
https://doi.org/10.1021/acs.joc.0c00598
Autor:
Alexey B, Mantsyzov, Mikhail N, Sokolov, Polina M, Ivantcova, Stefan, Bräse, Vladimir I, Polshakov, Konstantin V, Kudryavtsev
Publikováno v:
The Journal of organic chemistry. 85(14)
All possible variants of β-proline functionalized tripeptides consisting of homo/hetero chiral monomeric all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34fdd840d41acd9eada323fe26f6831c
https://pubmed.ncbi.nlm.nih.gov/32526142
https://pubmed.ncbi.nlm.nih.gov/32526142
Publikováno v:
Russian Chemical Reviews. 88:59-98
Nuclear magnetic resonance (NMR) spectroscopy is one of the leading biophysical methods used in the search for and design of physiologically active compounds considered as potential drugs. The review concerns modern NMR techniques used to study the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::739e4dcde82c0c19e6a9b24e6656eab2
https://doi.org/10.1070/rcr4836
https://doi.org/10.1070/rcr4836
Autor:
Elena V. Kugaevskaya, Sergey A. Kozin, Maria I. Indeykina, M. S. Zharkova, N. I. Solovyeva, Igor Popov, Alexey B. Mantsyzov, Alexander V. Veselovsky, Alexander A. Makarov, Eugene N. Nikolaev
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder. Amyloid-β (Aβ) aggregation is likely to be the major cause of AD. In contrast to humans and other mammals, that share the same Aβ sequence, rats and mice are invulnerable t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babf53779f50d6d4c50a7aca814f3db3
http://link.springer.com/article/10.1038/s41598-017-18567-5
http://link.springer.com/article/10.1038/s41598-017-18567-5
Autor:
Vladimir I. Polshakov, Alexey B. Mantsyzov, Sergey A. Kozin, Alexei A. Adzhubei, Sergey S. Zhokhov, Wouter van Beek, Alexandra A. Kulikova, Maria I. Indeykina, Vladimir A. Mitkevich, Alexander A. Makarov
Publikováno v:
Angewandte Chemie. 129:11896-11901
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767e6d1f2b3eeb1a068da5a8f3223764
https://doi.org/10.1002/ange.201704615
https://doi.org/10.1002/ange.201704615
Autor:
Vladimir I. Polshakov, Stefan Bräse, Andrei V. Churakov, Alexey B. Mantsyzov, Mikhail N. Sokolov, Konstantin V. Kudryavtsev, Nikolay S. Zefirov, Polina M. Ivantcova
Publikováno v:
Organic Letters. 18:4698-4701
β-Proline-functionalized dimers consisting of homochiral monomeric units were synthesized by a non-peptidic coupling method for the first time. The applied synthetic methodology is based on 1,3-dipolar cycloaddition chemistry of azomethine ylides an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8479d666c95419e4329c095f14fc99e
https://doi.org/10.1021/acs.orglett.6b02327
https://doi.org/10.1021/acs.orglett.6b02327
Autor:
Sergey A. Kozin, Y.Y. Kiseleva, Alexander A. Makarov, Sergey P. Radko, Svetlana A. Khmeleva, Alexey B. Mantsyzov, Vladimir A. Mitkevich
Publikováno v:
Journal of Alzheimer's disease : JAD. 63(2)
Zinc-induced aggregation of amyloid-β peptides (Aβ) is considered to contribute to the pathogenesis of Alzheimer's disease. While glycosaminoglycans (GAGs) that are commonly present in interneuronal space are known to enhance Aβ self-aggregation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33f4d6bac3fe985e393b43c2f0dacbd
https://pubmed.ncbi.nlm.nih.gov/29630553
https://pubmed.ncbi.nlm.nih.gov/29630553