Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Alexey Aleshin"'
Autor:
Maya Kansara, Neeru Bhardwaj, Subotheni Thavaneswaran, Chang Xu, Jessica K. Lee, Lo‐Bin Chang, Russell W. Madison, Frank Lin, Eugene Hsu, Vipul Kumar Patel, Alexey Aleshin, Geoffrey R. Oxnard, John Simes, Halla Nimeiri, David M. Thomas
Publikováno v:
Molecular Oncology, Vol 17, Iss 2, Pp 298-311 (2023)
There is an urgent need to identify biomarkers of early response that can accurately predict the benefit of immune checkpoint inhibitors (ICI). Patients receiving durvalumab/tremelimumab had tumor samples sequenced before treatment (baseline) to iden
Externí odkaz:
https://doaj.org/article/c442c4094d7d4fbb9a169db3f368978a
Autor:
Emily S. Lebow, Narek Shaverdian, Jordan E. Eichholz, Leah B. Kratochvil, Megan McCune, Yonina R. Murciano-Goroff, Justin Jee, Juliana Eng, Jamie E. Chaft, Mark G. Kris, Ekaterina Kalashnikova, Jordan Feeney, Carly Bess Scalise, Sumedha Sudhaman, Charuta C. Palsuledesai, Meenakshi Malhotra, Michael Krainock, Himanshu Sethi, Alexey Aleshin, Minetta C. Liu, Annemarie F. Shepherd, Abraham J. Wu, Charles B. Simone, Daphna Y. Gelblum, Kaylie A. Johnson, Charles M. Rudin, Daniel R. Gomez, Pedram Razavi, Jorge S. Reis-Filho, James M. Isbell, Bob T. Li, Andreas Rimner
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundSensitive and reliable biomarkers for early detection of recurrence are needed to improve post-definitive radiation risk stratification, disease management, and outcomes for patients with unresectable early-stage or locally advanced non-sma
Externí odkaz:
https://doaj.org/article/3ba4f11343744c078451496fafdf072c
Autor:
Thomas Powles, Amanda Young, Halla Nimeiri, Russell W. Madison, Alexander Fine, Daniel R. Zollinger, Yanmei Huang, Chang Xu, Ole V. Gjoerup, Vasily N. Aushev, Hsin-Ta Wu, Alexey Aleshin, Corey Carter, Nicole Davarpanah, Viraj Degaonkar, Pratyush Gupta, Sanjeev Mariathasan, Erica Schleifman, Zoe June Assaf, Geoffrey Oxnard, Priti S. Hegde
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionCirculating tumor DNA (ctDNA) detection postoperatively may identify patients with urothelial cancer at a high risk of relapse. Pragmatic tools building off clinical tumor next-generation sequencing (NGS) platforms could have the potentia
Externí odkaz:
https://doaj.org/article/b572edde61804227913dfd5bf63af668
Autor:
Georges Azzi, Shifra Krinshpun, Antony Tin, Minu Maninder, Allyson Koyen Malashevich, Meenakshi Malhotra, Ruben Ruiz Vega, Paul R. Billings, Angel Rodriguez, Alexey Aleshin
Publikováno v:
Case Reports in Oncology, Vol 15, Iss 2, Pp 473-479 (2022)
Triple-negative breast cancer (TNBC) is highly aggressive disease that is often refractory to surgery and multiple lines of therapy. Although the repertoire of FDA-approved treatments has expanded, there is an unmet need for biomarkers that can aid i
Externí odkaz:
https://doaj.org/article/8f07ca8fa5574b50856500ebf729166a
Autor:
John Yeakel, MD, Aarthi Kannan, BA, Nicole Hook Rattigan, PhD, Maki Yamamoto, MD, Alexey Aleshin, MD, MBA, Jeremy P. Harris, MPhil, MD, Ling Gao, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 18, Iss , Pp 94-98 (2021)
Externí odkaz:
https://doaj.org/article/83c88c6092e54f0f84f262e3833ad7ea
Autor:
Benjamin A. Weinberg, Emily R. Winslow, Mohammed Bayasi, Michael R. Krainock, Perry M. Olshan, Paul R. Billings, Alexey Aleshin
Publikováno v:
Case Reports in Oncology, Vol 14, Iss 3, Pp 1748-1753 (2021)
Currently, serum carcinoembryonic agent (CEA) along with contrast-enhanced imaging and colonoscopy are used for evaluation of recurrence of colorectal cancer. However, CEA is an unreliable and nonspecific biomarker that may fail to rise and signal re
Externí odkaz:
https://doaj.org/article/b2ecdf575244405abcf1871bcbc8bb02
Autor:
S. Y. Cindy Yang, Scott C. Lien, Ben X. Wang, Derek L. Clouthier, Youstina Hanna, Iulia Cirlan, Kelsey Zhu, Jeffrey P. Bruce, Samah El Ghamrasni, Marco A. J. Iafolla, Marc Oliva, Aaron R. Hansen, Anna Spreafico, Philippe L. Bedard, Stephanie Lheureux, Albiruni Razak, Vanessa Speers, Hal K. Berman, Alexey Aleshin, Benjamin Haibe-Kains, David G. Brooks, Tracy L. McGaha, Marcus O. Butler, Scott V. Bratman, Pamela S. Ohashi, Lillian L. Siu, Trevor J. Pugh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Although circulating tumour DNA (ctDNA) can predict immune checkpoint blockade (ICB) responses, its association with tumour biomarkers remains unknown. Here, the authors use ctDNA to inform exome and transcriptome profiling of >100 patients with 30 c
Externí odkaz:
https://doaj.org/article/2a55653c8f4a4ed888f461e4bdb5696f
Autor:
Charles J. Schneider, Michael Krainock, Allyson Koyen Malashevich, Meenakshi Malhotra, Perry Olshan, Paul R. Billings, Alexey Aleshin
Publikováno v:
Case Reports in Oncology, Vol 14, Iss 2, Pp 849-853 (2021)
Immunotherapy (IO) has increasingly been demonstrated to provide therapeutic benefit to patients with metastatic colorectal cancer (mCRC). However, only a subset of mCRC tumors respond to IO. Monitoring response with tumor biomarkers like carcinoembr
Externí odkaz:
https://doaj.org/article/718109250eb1486fa0b03794c8bc919a
Autor:
Zeynep Eroglu, Joe Ensor, Meenakshi Malhotra, Paul Billings, Angel Rodriguez, Alexey Aleshin, Ling Gao, Sarah Sawyer, Pashtoon Murtaza Kasi, Sascha Ellers, George Ansstas, Michael Krainock, Sakti Chakrabarti, Andrew Poklepovic, Minu Maninder
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/1710b670c7d04923bb1d5cd95028e149
Autor:
Mark Jesus M. Magbanua, Wen Li, Denise M. Wolf, Christina Yau, Gillian L. Hirst, Lamorna Brown Swigart, David C. Newitt, Jessica Gibbs, Amy L. Delson, Ekaterina Kalashnikova, Alexey Aleshin, Bernhard Zimmermann, A. Jo Chien, Debu Tripathy, Laura Esserman, Nola Hylton, Laura van ‘t Veer
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract We investigated whether serial measurements of circulating tumor DNA (ctDNA) and functional tumor volume (FTV) by magnetic resonance imaging (MRI) can be combined to improve prediction of pathologic complete response (pCR) and estimation of
Externí odkaz:
https://doaj.org/article/fc14e93945954cfb88f54bbbdcc007fe