Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Alexey A, Lugovskoy"'
Autor:
Melissa L. Geddie, Dmitri B. Kirpotin, Neeraj Kohli, Tad Kornaga, Bjoern Boll, Maja Razlog, Daryl C. Drummond, Alexey A. Lugovskoy
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Antibody-directed nanotherapeutics (ADNs) represent a promising delivery platform for selective delivery of an encapsulated drug payload to the site of disease that improves the therapeutic index. Although both single-chain Fv (scFv) and Fab antibody
Externí odkaz:
https://doaj.org/article/9d2891dc79f643129c3b3b205c1860ca
Autor:
Alexey A. Lugovskoy, Ulrik B. Nielsen, Birgit Schoeberl, Kenneth J. Olivier, Brian D. Harms, Yang Jiao, Maja Razlog, Rachel Rennard, Neeraj Kohli, Lihui Xu, Victoria Rimkunas, Jian Tang, Sergio Iadevaia, Sharlene Adams, Jason Baum, Bryan W. Johnson, Jonathan B. Fitzgerald
PDF - 111K, Additional details on the implementation and training of the mechanistic model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a54401ccec2fdca3751258fe817721
https://doi.org/10.1158/1535-7163.22500898.v1
https://doi.org/10.1158/1535-7163.22500898.v1
Autor:
Alexey A. Lugovskoy, Ulrik B. Nielsen, Birgit Schoeberl, Kenneth J. Olivier, Brian D. Harms, Yang Jiao, Maja Razlog, Rachel Rennard, Neeraj Kohli, Lihui Xu, Victoria Rimkunas, Jian Tang, Sergio Iadevaia, Sharlene Adams, Jason Baum, Bryan W. Johnson, Jonathan B. Fitzgerald
Although inhibition of the insulin-like growth factor (IGF) signaling pathway was expected to eliminate a key resistance mechanism for EGF receptor (EGFR)-driven cancers, the effectiveness of IGF-I receptor (IGF-IR) inhibitors in clinical trials has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63aadf5ac0a5228ff209cf3c30de8a8a
https://doi.org/10.1158/1535-7163.c.6536614.v1
https://doi.org/10.1158/1535-7163.c.6536614.v1
Autor:
Alexey A. Lugovskoy, Ulrik B. Nielsen, Birgit Schoeberl, Kenneth J. Olivier, Brian D. Harms, Yang Jiao, Maja Razlog, Rachel Rennard, Neeraj Kohli, Lihui Xu, Victoria Rimkunas, Jian Tang, Sergio Iadevaia, Sharlene Adams, Jason Baum, Bryan W. Johnson, Jonathan B. Fitzgerald
PDF - 711K, Supplemental Figure S1. Schematic representation of components of IGF-1R/ErbB3 merged mechanistic signaling model. Supplemental Table S1. Mean ligand-stimulated pAKT (S473) levels (A) or simulated levels (B) in BxPC-3, AdRr and MCF7 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9badea55c07244efa7d070174e73781
https://doi.org/10.1158/1535-7163.22500901
https://doi.org/10.1158/1535-7163.22500901
Autor:
Alexey A. Lugovskoy, Ulrik B. Nielsen, Birgit Schoeberl, Kenneth J. Olivier, Brian D. Harms, Yang Jiao, Maja Razlog, Rachel Rennard, Neeraj Kohli, Lihui Xu, Victoria Rimkunas, Jian Tang, Sergio Iadevaia, Sharlene Adams, Jason Baum, Bryan W. Johnson, Jonathan B. Fitzgerald
PDF - 91K, Supplementary Figure Legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1d1c7471f02ecb8c6eef01f33fceae
https://doi.org/10.1158/1535-7163.22500904.v1
https://doi.org/10.1158/1535-7163.22500904.v1
Autor:
Alexey A. Lugovskoy, Vasileios Askoxylakis, Robert M. Straubinger, J. Marc Pipas, Birgit Schoeberl, Ulrik B. Nielsen, Daryl C. Drummond, Chrystal U. Louis, Akos Czibere, Charlene Minx, Jason Baum, Sergio Iadevaia, Troy Bloom, Gege Tan, Lin Nie, Victoria Rimkunas, Michael D. Curley, Sharlene Adams, Emily A. Pace, Adam J. Camblin
Supplemental Figure S2: Istiratumab inhibits growth factor-induced AKT phosphorylation across a pancreatic cancer cell line panel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fbe3030b674cb44ac8311785ed7e8d
https://doi.org/10.1158/1078-0432.22465556
https://doi.org/10.1158/1078-0432.22465556
Autor:
Alexey A. Lugovskoy, Vasileios Askoxylakis, Robert M. Straubinger, J. Marc Pipas, Birgit Schoeberl, Ulrik B. Nielsen, Daryl C. Drummond, Chrystal U. Louis, Akos Czibere, Charlene Minx, Jason Baum, Sergio Iadevaia, Troy Bloom, Gege Tan, Lin Nie, Victoria Rimkunas, Michael D. Curley, Sharlene Adams, Emily A. Pace, Adam J. Camblin
Table S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9363760c6e52df414b79366e520ff74c
https://doi.org/10.1158/1078-0432.22465529
https://doi.org/10.1158/1078-0432.22465529
Autor:
Alexey A. Lugovskoy, Vasileios Askoxylakis, Robert M. Straubinger, J. Marc Pipas, Birgit Schoeberl, Ulrik B. Nielsen, Daryl C. Drummond, Chrystal U. Louis, Akos Czibere, Charlene Minx, Jason Baum, Sergio Iadevaia, Troy Bloom, Gege Tan, Lin Nie, Victoria Rimkunas, Michael D. Curley, Sharlene Adams, Emily A. Pace, Adam J. Camblin
Purpose: Insulin-like growth factor receptor 1 (IGF-1R) is critically involved in pancreatic cancer pathophysiology, promoting cancer cell survival and therapeutic resistance. Assessment of IGF-1R inhibitors in combination with standard-of-care chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67565d75c08617bb5e48fee4d51b15c3
https://doi.org/10.1158/1078-0432.c.6526055.v1
https://doi.org/10.1158/1078-0432.c.6526055.v1
Autor:
Alexey A. Lugovskoy, Vasileios Askoxylakis, Robert M. Straubinger, J. Marc Pipas, Birgit Schoeberl, Ulrik B. Nielsen, Daryl C. Drummond, Chrystal U. Louis, Akos Czibere, Charlene Minx, Jason Baum, Sergio Iadevaia, Troy Bloom, Gege Tan, Lin Nie, Victoria Rimkunas, Michael D. Curley, Sharlene Adams, Emily A. Pace, Adam J. Camblin
Supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f3bcbb0f2da6bc498d87084abe5f06
https://doi.org/10.1158/1078-0432.22465538.v1
https://doi.org/10.1158/1078-0432.22465538.v1
Autor:
Ivan Suprun, Ilnur Balapanov, Ilya Stepanov, Sergey Vyacheslavovich Tokmakov, Alexey Pavlovich Lugovskoy
Publikováno v:
Scientia Horticulturae. 253:322-326
To date, the current issue is the history of the walnut spreading after last glacial maximum (LGM) as well as the role of human in this process and his impact on the population structure. Large-scale studies of the walnut loci microsatellite diversit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11c87ffa91062f20be9abaff8bfd53f9
https://doi.org/10.1016/j.scienta.2019.04.014
https://doi.org/10.1016/j.scienta.2019.04.014