Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Alexey A, Leontovich"'
Autor:
Evanthia Galanis, Katharine E. Dooley, S. Keith Anderson, Cheyne B. Kurokawa, Xiomara W. Carrero, Joon H. Uhm, Mark J. Federspiel, Alexey A. Leontovich, Ileana Aderca, Kimberly B. Viker, Julie E. Hammack, Randolph S. Marks, Steven I. Robinson, Derek R. Johnson, Timothy J. Kaufmann, Jan C. Buckner, Daniel H. Lachance, Terry C. Burns, Caterina Giannini, Aditya Raghunathan, Ianko D. Iankov, Ian F. Parney
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Measles virus (MV) vaccine strains have shown significant preclinical antitumor activity against glioblastoma (GBM), the most lethal glioma histology. In this first in human trial (NCT00390299), a carcinoembryonic antigen-expressing oncolyti
Externí odkaz:
https://doaj.org/article/436353bf6b554a7ca56ec210185c93df
Autor:
Shankar Suman, Wendy K. Nevala, Alexey A. Leontovich, Caitlin Ward, James W. Jakub, Yohan Kim, Liyi Geng, Noah A. Stueven, Chathu L. Atherton, Raymond M. Moore, Jill M. Schimke, Fabrice Lucien-Matteoni, Sarah A. McLaughlin, Svetomir N. Markovic
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 837 (2024)
CD36 expression in both immune and non-immune cells is known to be directly involved in cancer metastasis. Extracellular vesicles (EVs) secreted by malignant melanocytes play a vital role in developing tumor-promoting microenvironments, but it is unc
Externí odkaz:
https://doaj.org/article/aea87e2bdc6e4ec9bf216716f6fc9d04
Autor:
Rachel L. G. Maus, Alexey A. Leontovich, Raymond M. Moore, Zachary Fogarty, Ruifeng Guo, Tara M. Davidson, Burak Tekin, Chathu Atherton, Jill M. Schimke, Betty A. Dicke, Benjamin J. Chen, Svetomir N. Markovic
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionImmune cell infiltration into the tumor microenvironment is generally associated with favorable clinical outcomes in solid tumors. However, the dynamic interplay among distinct immune cell subsets within the tumor-immune microenvironment
Externí odkaz:
https://doaj.org/article/4902bf15b57e47ae8c4ce56cadc34cad
Autor:
Harold P. Frisch, Allan Sprau, Virginia F. McElroy, James D. Turner, Laura R. E. Becher, Wendy K. Nevala, Alexey A. Leontovich, Svetomir N. Markovic
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-25 (2021)
Abstract Background Recent clinical advances in cancer immuno-therapeutics underscore the need for improved understanding of the complex relationship between cancer and the multiple, multi-functional, inter-dependent, cellular and humoral mediators/r
Externí odkaz:
https://doaj.org/article/930c7d1f94574c8eb7a2eff0c0914d00
Autor:
Alexey A. Leontovich, Mohammad Jalalirad, Jeffrey L. Salisbury, Lisa Mills, Candace Haddox, Mark Schroeder, Ann Tuma, Maria E. Guicciardi, Luca Zammataro, Mario W. Gambino, Angela Amato, Aldo Di Leonardo, James McCubrey, Carol A. Lange, Minetta Liu, Tufia Haddad, Matthew Goetz, Judy Boughey, Jann Sarkaria, Liewei Wang, James N. Ingle, Evanthia Galanis, Antonino B. D’Assoro
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-19 (2018)
Abstract Background Development of distant metastases involves a complex multistep biological process termed the invasion-metastasis cascade, which includes dissemination of cancer cells from the primary tumor to secondary organs. NOTCH developmental
Externí odkaz:
https://doaj.org/article/86a3724d1a17429ca5f5edb8bc06a69b
Autor:
Yiyi Yan, Alexey A Leontovich, Michael J Gerdes, Keyur Desai, Jinhong Dong, Anup Sood, Alberto Santamaria-Pang, Aaron S Mansfield, Chrystal Chadwick, Rong Zhang, Wendy K Nevala, Thomas J Flotte, Fiona Ginty, Svetomir N Markovic
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0216485 (2019)
A systemic analysis of the tumor-immune interactions within the heterogeneous tumor microenvironment is of particular importance for understanding the antitumor immune response. We used multiplexed immunofluorescence to elucidate cellular spatial int
Externí odkaz:
https://doaj.org/article/d834614bc7fc4b62b710701617d4c7b5
Autor:
Elizabeth Ann L. Enninga, Aoife M. Egan, Layan Alrahmani, Alexey A. Leontovich, Rodrigo Ruano, Michael P. Sarras
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
The Center for Disease Control and Prevention ranks diabetes mellitus (DM) as the seventh leading cause of death in the USA. The most prevalent forms of DM include Type 2 DM, Type 1 DM, and gestational diabetes mellitus (GDM). While the acute problem
Externí odkaz:
https://doaj.org/article/7029b56b38f84aac8124d51280939660
Autor:
Svetomir N. Markovic, Yiyi Yan, Betty A. Dicke, Jill M. Schimke, Ruifeng Guo, Thomas J. Flotte, Wendy K. Nevala, Laura Becher, Raymond M. Moore, Alexey A. Leontovich, Rachel L.G. Maus
Phenotypic Cell Classification Tree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebacac4564579b8b3cb3634460e2a4b
https://doi.org/10.1158/2767-9764.22544142.v1
https://doi.org/10.1158/2767-9764.22544142.v1
Autor:
Svetomir N. Markovic, Yiyi Yan, Betty A. Dicke, Jill M. Schimke, Ruifeng Guo, Thomas J. Flotte, Wendy K. Nevala, Laura Becher, Raymond M. Moore, Alexey A. Leontovich, Rachel L.G. Maus
Summary data of FOV distribution, single cells segmented, classified and clinical response to therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e05ff9ef605ede3b00f40d173cf692
https://doi.org/10.1158/2767-9764.22544133.v1
https://doi.org/10.1158/2767-9764.22544133.v1
Autor:
Svetomir N. Markovic, Yiyi Yan, Betty A. Dicke, Jill M. Schimke, Ruifeng Guo, Thomas J. Flotte, Wendy K. Nevala, Laura Becher, Raymond M. Moore, Alexey A. Leontovich, Rachel L.G. Maus
Antibody reagents and validation for MxIF panel design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3691a20a6ec1f9ffdeb952832d8402f0
https://doi.org/10.1158/2767-9764.22544136
https://doi.org/10.1158/2767-9764.22544136