Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Alexey A, Gavrilov"'
Autor:
Alexey A. Gavrilov, Grigory S. Evko, Aleksandra A. Galitsyna, Sergey V. Ulianov, Tatiana V. Kochetkova, Alexander Y. Merkel, Alexander V. Tyakht, Sergey V. Razin
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract Proximity ligation approaches, which are widely used to study the spatial organization of the genome, also make it possible to reveal patterns of RNA-DNA interactions. Here, we use RedC, an RNA-DNA proximity ligation approach, to assess the
Externí odkaz:
https://doaj.org/article/239e1657be44420789f5ac60e9294ed5
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Cohesin is a key organizer of chromatin folding in eukaryotic cells. The two main activities of this ring-shaped protein complex are the maintenance of sister chromatid cohesion and the establishment of long-range DNA–DNA interactions thro
Externí odkaz:
https://doaj.org/article/a6fa8998948642d7b75363cb20dd92f4
Autor:
Artem V. Luzhin, Arkadiy K. Golov, Alexey A. Gavrilov, Artem K. Velichko, Sergey V. Ulianov, Sergey V. Razin, Omar L. Kantidze
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Chromatin loops represent one of the major levels of hierarchical folding of the genome. Although the situation is evolving, current methods have various difficulties with the accurate mapping of loops even in mammalian Hi-C data, and most o
Externí odkaz:
https://doaj.org/article/69ccde0abe7745c6ae22aa14c46e9b5f
Autor:
Sergey V. Ulianov, Vlada V. Zakharova, Aleksandra A. Galitsyna, Pavel I. Kos, Kirill E. Polovnikov, Ilya M. Flyamer, Elena A. Mikhaleva, Ekaterina E. Khrameeva, Diego Germini, Mariya D. Logacheva, Alexey A. Gavrilov, Alexander S. Gorsky, Sergey K. Nechaev, Mikhail S. Gelfand, Yegor S. Vassetzky, Alexander V. Chertovich, Yuri Y. Shevelyov, Sergey V. Razin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Genomes are partitioned into topologically associating domains (TADs). Here the authors present single-nucleus Hi-C maps in Drosophila at 10 kb resolution, demonstrating the presence of chromatin compartments in individual nuclei, and partitioning of
Externí odkaz:
https://doaj.org/article/8dcfb2d70fc24ab89ca4dad46c6324c9
Autor:
Sergey V. Ulianov, Semen A. Doronin, Ekaterina E. Khrameeva, Pavel I. Kos, Artem V. Luzhin, Sergei S. Starikov, Aleksandra A. Galitsyna, Valentina V. Nenasheva, Artem A. Ilyin, Ilya M. Flyamer, Elena A. Mikhaleva, Mariya D. Logacheva, Mikhail S. Gelfand, Alexander V. Chertovich, Alexey A. Gavrilov, Sergey V. Razin, Yuri Y. Shevelyov
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The role of the nuclear lamina (NL) in chromatin architecture is still poorly understood. Here, the authors provide evidence that disruption of the NL in Drosophila cells leads to overall chromatin compaction and repositioning from the nuclear envelo
Externí odkaz:
https://doaj.org/article/019c5aaf61ed41efb63d52b8af38836b
Autor:
Alexey A. Gavrilov, Igor I. Potemkin
Publikováno v:
The Journal of Physical Chemistry B. 127:1479-1489
Autor:
Sergey V. Ulianov, Aleksandra A. Galitsyna, Ilya M. Flyamer, Arkadiy K. Golov, Ekaterina E. Khrameeva, Maxim V. Imakaev, Nezar A. Abdennur, Mikhail S. Gelfand, Alexey A. Gavrilov, Sergey V. Razin
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-19 (2017)
Abstract Background In homeotherms, the alpha-globin gene clusters are located within permanently open genome regions enriched in housekeeping genes. Terminal erythroid differentiation results in dramatic upregulation of alpha-globin genes making the
Externí odkaz:
https://doaj.org/article/5faf277341c547219a288c47cf1b9b1f
Autor:
Tatiana V. Egorova, Evgenia D. Zotova, Denis A. Reshetov, Anna V. Polikarpova, Svetlana G. Vassilieva, Dmitry V. Vlodavets, Alexey A. Gavrilov, Sergey V. Ulianov, Vladimir L. Buchman, Alexei V. Deykin
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 4 (2019)
Exon skipping is a promising strategy for Duchenne muscular dystrophy (DMD) disease-modifying therapy. To make this approach safe, ensuring that excluding one or more exons will restore the reading frame and that the resulting protein will retain cri
Externí odkaz:
https://doaj.org/article/316b1ecf089f4dba993bcc8630736791
Autor:
Subhasish Sahoo, Yulia D. Gordievskaya, Kamal Bauri, Alexey A. Gavrilov, Elena Yu. Kramarenko, Priyadarsi De
Publikováno v:
Macromolecules. 55:1139-1152
Autor:
Rustam A. Gumerov, Vladimir Yu. Rudyak, Alexey A. Gavrilov, Alexander V. Chertovich, Igor I. Potemkin
Publikováno v:
Soft Matter. 18:3738-3747
Polymer microgels synthesized in silico were studied at liquid–liquid interface via mesoscopic computer simulations and compared to microgels with ideal (diamond-like) structure.