Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Alexey, Ushmorov"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The germinal center (GC) reaction is a key process during an adaptive immune response to T cell specific antigens. GCs are specialized structures within secondary lymphoid organs, in which B cell proliferation, somatic hypermutation and antibody affi
Externí odkaz:
https://doaj.org/article/55ebb4d04f424abda17ff4eadfdfd995
Autor:
Franz Ketzer, Hend Abdelrasoul, Mona Vogel, Ralf Marienfeld, Markus Müschen, Hassan Jumaa, Thomas Wirth, Alexey Ushmorov
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract The D-type cyclins (CCND1, CCND2, and CCND3) in association with CDK4/6 are known drivers of cell cycle progression. We reported previously that inactivation of FOXO1 confers growth arrest and apoptosis in B-ALL, partially mediated by subseq
Externí odkaz:
https://doaj.org/article/cd3fcf0a0bbb43f9a95cf28d3dfc64d4
Autor:
Franz Ketzer, Hend Abdelrasoul, Mona Vogel, Ralf Marienfeld, Markus Müschen, Hassan Jumaa, Thomas Wirth, Alexey Ushmorov
Publikováno v:
Oncogenesis
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
The D-type cyclins (CCND1, CCND2, and CCND3) in association with CDK4/6 are known drivers of cell cycle progression. We reported previously that inactivation of FOXO1 confers growth arrest and apoptosis in B-ALL, partially mediated by subsequent depl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbdbf0c4da1a691ab482b278c210ca4
Autor:
Sabine Iberl, Alexey Ushmorov, Jochen Grassinger, Roland Christian Schelker, Wolfgang Herr, Christina Hart, Gunnar Müller, Mindaugas Andrulis, Martin Vogelhuber
Publikováno v:
Blood Cells, Molecules, and Diseases. 76:78-81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558902e8a33ab49eae02b81820df9504
https://doi.org/10.1016/j.bcmd.2019.02.005
https://doi.org/10.1016/j.bcmd.2019.02.005
Autor:
Simon Laban, Cornelia Brunner, F Frank, Jens Greve, Alexey Ushmorov, Ralf Marienfeld, Ninel Azoitei, Pj. Schuler, J Döscher, E Goldberg-Bockhorn, J Dünser, M Wilkat, M Brhel, R Drees, Tk. Hoffmann, Marie-Nicole Theodoraki, H Bast
Publikováno v:
Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e04519787cdf59b98bbaf52ada46c68f
https://doi.org/10.1055/s-0040-1711572
https://doi.org/10.1055/s-0040-1711572
Autor:
F Frank, Pj. Schuler, Ralf Marienfeld, Jens Greve, J Dünser, E Goldberg-Bockhorn, M Wilkat, Ninel Azoitei, M Brhel, Cornelia Brunner, Alexey Ushmorov, Simon Laban, R Drees, J Döscher, Marie-Nicole Theodoraki, Tk. Hoffmann, H Bast
Publikováno v:
Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd466fcdaf899d62b88d4b8d0c1de7a8
https://doi.org/10.1055/s-0040-1710934
https://doi.org/10.1055/s-0040-1710934
Autor:
Thomas Wirth, Alexey Ushmorov, Klaus-Michael Debatin, Salih Demir, SM Eckhoff, Karlheinz Holzmann, Lüder Hinrich Meyer, Clarissa D. Osswald, Fan Wang, Thomas Maier, Felix Seyfried, Franziska Gehringer, Stefanie Enzenmüller
Publikováno v:
Blood. 131:2929-2942
The FOXO1 transcription factor plays an essential role in the regulation of proliferation and survival programs at early stages of B-cell differentiation. Here, we show that tightly regulated FOXO1 activity is essential for maintenance of B-cell prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcee2701b3fbb5d6b8bfb93ca5ecbcb
https://doi.org/10.1182/blood-2017-10-813576
https://doi.org/10.1182/blood-2017-10-813576
Autor:
Alexey Ushmorov, Franziska Gehringer
Publikováno v:
Blood
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause severe vascular complications associated with endothelial dysfunction and systemic inflammation. COVID19-specific IgG are detectable within a week of infection. Long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0816d733d08ec3677d22895266030712
https://doi.org/10.1182/blood.2021012518
https://doi.org/10.1182/blood.2021012518
Autor:
Stephanie E. Weissinger, Peter Möller, Lotteke J Y M Swier, Franziska Gehringer, Alexey Ushmorov, Thomas Wirth
Publikováno v:
Cancers
Volume 11
Issue 10
Cancers, Vol 11, Iss 10, p 1427 (2019)
Volume 11
Issue 10
Cancers, Vol 11, Iss 10, p 1427 (2019)
The FOXO1 transcription factor plays a central role in the proliferation and survival of B cells at several stages of differentiation. B cell malignancies, with exception of classical Hodgkin lymphoma, maintain expression of FOXO1 at levels character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aedf5145dc2783dae2d5560f63728bb5
Publikováno v:
Leukemia
In addition to oncogenic MYC translocations, Burkitt lymphoma (BL) depends on the germinal centre (GC) dark zone (DZ) B cell survival and proliferation programme, which is characterized by relatively low PI3K-AKT activity. Paradoxically, PI3K-AKT act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80203db520a7eabec767a3f40bff2046
https://pubmed.ncbi.nlm.nih.gov/31719683
https://pubmed.ncbi.nlm.nih.gov/31719683