Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Alexey, Ruzin"'
Autor:
Julio Diaz Caballero, Rachel M. Wheatley, Natalia Kapel, Carla López-Causapé, Thomas Van der Schalk, Angus Quinn, Liam P. Shaw, Lois Ogunlana, Claudia Recanatini, Basil Britto Xavier, Leen Timbermont, Jan Kluytmans, Alexey Ruzin, Mark Esser, Surbhi Malhotra-Kumar, Antonio Oliver, R. Craig MacLean
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Antibiotic resistance poses a global health threat, but the within-host drivers of resistance remain poorly understood. Pathogen populations are often assumed to be clonal within hosts, and resistance is thought to emerge due to selection fo
Externí odkaz:
https://doaj.org/article/c8f2767653e74ecc9aa65a300ff1615f
Autor:
Jean Chastre, Bruno François, Marc Bourgeois, Apostolos Komnos, Ricard Ferrer, Galia Rahav, Nicolas De Schryver, Alain Lepape, Iftihar Koksal, Charles-Edouard Luyt, Miguel Sánchez-García, Antoni Torres, Philippe Eggimann, Despoina Koulenti, Thomas L. Holland, Omar Ali, Kathryn Shoemaker, Pin Ren, Julien Sauser, Alexey Ruzin, David E. Tabor, Ahmad Akhgar, Yuling Wu, Yu Jiang, Antonio DiGiandomenico, Susan Colbert, Drieke Vandamme, Frank Coenjaerts, Surbhi Malhotra-Kumar, Leen Timbermont, Antonio Oliver, Olivier Barraud, Terramika Bellamy, Marc Bonten, Herman Goossens, Colin Reisner, Mark T. Esser, Hasan S. Jafri, The COMBACTE-MAGNET EVADE Study Group
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-14 (2022)
Abstract Background Ventilator-associated pneumonia caused by Pseudomonas aeruginosa (PA) in hospitalised patients is associated with high mortality. The effectiveness of the bivalent, bispecific mAb MEDI3902 (gremubamab) in preventing PA nosocomial
Externí odkaz:
https://doaj.org/article/b646d8fc362c477c9d9d20ee008f3057
Autor:
Thomas Ewout van der Schalk, Jasmine Coppens, Leen Timbermont, Agata Turlej-Rogacka, Liesbet Van Heirstraeten, Matilda Berkell, Li Yu, Christine Lammens, Basil Britto Xavier, Veerle Matheeussen, Margareta Ieven, Michael McCarthy, Philippe G. Jorens, Alexey Ruzin, Mark T. Esser, Samir Kumar-Singh, Herman Goossens, Surbhi Malhotra-Kumar
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 10, Iss 1, Pp 1-10 (2021)
Abstract Introduction Pseudomonas aeruginosa is a common cause of ventilator-associated pneumonia (VAP). Rapid and accurate detection of lower respiratory tract colonization and/or infection with P. aeruginosa may advise targeted preventive (antibody
Externí odkaz:
https://doaj.org/article/2c041679eeed4e209132e3d63a661cb1
Autor:
Rachel Wheatley, Julio Diaz Caballero, Natalia Kapel, Fien H. R. de Winter, Pramod Jangir, Angus Quinn, Ester del Barrio-Tofiño, Carla López-Causapé, Jessica Hedge, Gabriel Torrens, Thomas Van der Schalk, Basil Britto Xavier, Felipe Fernández-Cuenca, Angel Arenzana, Claudia Recanatini, Leen Timbermont, Frangiscos Sifakis, Alexey Ruzin, Omar Ali, Christine Lammens, Herman Goossens, Jan Kluytmans, Samir Kumar-Singh, Antonio Oliver, Surbhi Malhotra-Kumar, Craig MacLean
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Here, following a patient with severe acute Pseudomonas aeruginosa infection, the authors combine comprehensive isolate characterization from lung and gut samples (>100 isolates) and patient clinical data to provide insights into bacterial responses
Externí odkaz:
https://doaj.org/article/288e3c2784b04e7b8be0262d7398b88b
Autor:
Annefleur C. Langedijk, Robert Jan Lebbink, Christiana Naaktgeboren, Anouk Evers, Marco C. Viveen, Anne Greenough, Terho Heikkinen, Renato T. Stein, Peter Richmond, Federico Martinón-Torres, Marta Nunes, Mitsuaki Hosoya, Christian Keller, Monika Bauck, Robert Cohen, Jesse Papenburg, Jeffrey Pernica, Marije P. Hennus, Hong Jin, David E. Tabor, Andrev Tovchigrechko, Alexey Ruzin, Michael E. Abram, Deidre Wilkins, Joanne G. Wildenbeest, Leyla Kragten-Tabatabaie, Frank E. J. Coenjaerts, Mark T. Esser, Louis J. Bont
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Respiratory syncytial virus (RSV) is a global cause of severe respiratory morbidity and mortality in infants. While preventive and therapeutic interventions are being developed, including antivirals, vaccines and monoclonal antibo
Externí odkaz:
https://doaj.org/article/7dca7f74e743453a86b509c336fc6ee6
Autor:
Deidre Wilkins, Anastasia A Aksyuk, Alexey Ruzin, Kevin M Tuffy, Tina Green, Rebecca Greway, Brittany Fikes, Cyrille J Bonhomme, Mark T Esser, Elizabeth J Kelly
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 4, Pp n/a-n/a (2022)
Abstract Objectives Robust, quantitative serology assays are required to accurately measure antibody levels following vaccination and natural infection. We present validation of a quantitative, multiplex, SARS‐CoV‐2, electrochemiluminescent (ECL)
Externí odkaz:
https://doaj.org/article/185998943a9c4bd88730c7fd662763ef
Autor:
Jasmine Coppens, Liesbet Van Heirstraeten, Alexey Ruzin, Li Yu, Leen Timbermont, Christine Lammens, Veerle Matheeussen, Michael McCarthy, Philippe Jorens, Margareta Ieven, Samir Kumar-Singh, Herman Goossens, Surbhi Malhotra-Kumar
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 8, Iss 1, Pp 1-7 (2019)
Abstract Introduction Staphylococcus aureus (S. aureus) is a common cause of ventilator-associated pneumonia. Rapid and accurate detection of lower respiratory tract colonization and/or infection with S. aureus may inform targeted preventive and ther
Externí odkaz:
https://doaj.org/article/90338ea4ae86422d937eee730288a00f
Autor:
Batu K Sharma‐Kuinkel, Christine Tkaczyk, Jessica Bonnell, Li Yu, Andrey Tovchigrechko, David E Tabor, Lawrence P Park, Felicia Ruffin, Mark T Esser, Bret R Sellman, Vance G Fowler Jr., Alexey Ruzin
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 7, Pp n/a-n/a (2019)
Abstract Objective To understand the relationships of Staphylococcus aureus (SA) bacteremic pneumonia (SABP) outcome with patient‐specific and SA‐specific variables. Methods We analysed SA bloodstream isolates and matching sera in SABP patients b
Externí odkaz:
https://doaj.org/article/8dae2678a14549b98b9ee2c93f92a312
Autor:
Mina Mostafavi, Lisha Wang, Lili Xie, Kenneth T. Takeoka, Daryl L. Richie, Fergal Casey, Alexey Ruzin, William S. Sawyer, Christopher M. Rath, Jun-Rong Wei, Charles R. Dean
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Tight coordination of inner and outer membrane biosynthesis is very important in Gram-negative bacteria. Biosynthesis of the lipid A moiety of lipopolysaccharide, which comprises the outer leaflet of the outer membrane has garnered interest
Externí odkaz:
https://doaj.org/article/1e5ff2b427e345449955f5246fb5ce69
Autor:
Alexey Ruzin, Susan T Pastula, Elizabeth Levin-Sparenberg, Xiaohui Jiang, Jon Fryzek, Andrey Tovchigrechko, Bin Lu, Yanping Qi, Hui Liu, Hong Jin, Li Yu, Judith Hackett, Tonya Villafana, Mark T Esser
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200319 (2018)
BACKGROUND:Respiratory syncytial virus (RSV) is an established cause of serious lower respiratory disease in infants, elderly and high-risk populations. The OUTSMART surveillance program aims to characterize patient populations and currently circulat
Externí odkaz:
https://doaj.org/article/536b094015fd41a4bfd0921ace87e6e8