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Autor:
Dmitry, Tyrsin, Sergey, Chuvpilo, Alexey, Matskevich, Daniil, Nemenov, Paula S, Römer, Paula, Tabares, Thomas, Hünig
Publikováno v:
Clinical and experimental rheumatology. 34(4 Suppl 98)
CD28 superagonists (CD28SA) are CD28-specific monoclonal antibodies which are able to activate T-cells without overt TCR engagement. In rodents, CD28SA efficiently activate regulatory T-cells and are therapeutically effective in multiple models of au