Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Alexey, Fomenkov"'
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Although restriction-modification systems are found in both Eubacterial and Archaeal kingdoms, comparatively less is known about patterns of DNA methylation and genome defense systems in archaea. Here we report the complete closed genome sequence and
Externí odkaz:
https://doaj.org/article/e67930c2d36b4e0bb1831482f90e64dd
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010389 (2022)
Phosphorothioation (PT), in which a non-bridging oxygen is replaced by a sulfur, is one of the rare modifications discovered in bacteria and archaea that occurs on the sugar-phosphate backbone as opposed to the nucleobase moiety of DNA. While PT modi
Externí odkaz:
https://doaj.org/article/45b880e9a155483798f15e35c95298f3
Autor:
Julie Zaworski, Oyut Dagva, Julius Brandt, Chloé Baum, Laurence Ettwiller, Alexey Fomenkov, Elisabeth A Raleigh
Publikováno v:
PLoS Genetics, Vol 18, Iss 4, p e1009943 (2022)
Understanding mechanisms that shape horizontal exchange in prokaryotes is a key problem in biology. A major limit on DNA entry is imposed by restriction-modification (RM) processes that depend on the pattern of DNA modification at host-specified site
Externí odkaz:
https://doaj.org/article/4eec78c6666d42edac1300f7a82c322a
Autor:
Bianca Stenmark, Lorraine Eriksson, Sara Thulin Hedberg, Brian P. Anton, Alexey Fomenkov, Richard J. Roberts, Paula Mölling
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract A rising incidence of meningococcal serogroup W disease has been evident in many countries worldwide. Serogroup W isolates belonging to the sequence type (ST)-11 clonal complex have been associated with atypical symptoms and increased case f
Externí odkaz:
https://doaj.org/article/064fcb38cc664e919d2a01b417b66c1b
Autor:
Nikolai V. Ravin, Tatyana S. Rudenko, Dmitry D. Smolyakov, Alexey V. Beletsky, Andrey L. Rakitin, Nikita D. Markov, Alexey Fomenkov, Luo Sun, Richard J. Roberts, Andrey A. Novikov, Olga V. Karnachuk, Margarita Y. Grabovich
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Two strains of filamentous, colorless sulfur bacteria were isolated from bacterial fouling in the outflow of hydrogen sulfide-containing waters from a coal mine (Thiothrix sp. Ku-5) and on the seashore of the White Sea (Thiothrix sp. AS). Metagenome-
Externí odkaz:
https://doaj.org/article/8e003ad6659247a7b320ddb4becf7d6e
Autor:
Shuang-yong Xu, Elena V. Zemlyanskaya, Danila A. Gonchar, Zhiyi Sun, Peter Weigele, Alexey Fomenkov, Sergey Kh Degtyarev, Richard J. Roberts
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
BisI is a sequence-specific and 5-methylcytosine (m5C)-dependent restriction endonuclease (REase), that cleaves the modified DNA sequence Gm5CNGC (G indicates that the cytosine opposite to G is modified). We expressed and purified a number of BisI ho
Externí odkaz:
https://doaj.org/article/aca65bf9f5864f688616e2cad4d9cd6b
Autor:
Julie Zaworski, Oyut Dagva, Anthony W Kingston, Alexey Fomenkov, Richard D Morgan, Lionello Bossi, Elisabeth A Raleigh
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 9 (2021)
AbstractThe Salmonella research community has used strains and bacteriophages over decades, exchanging useful new isolates among laboratories for the study of cell surface antigens, metabolic pathways and restriction-modification (RM) studies. Here w
Externí odkaz:
https://doaj.org/article/9207451d5f03432da52cea6628d61dc7
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The SARS-CoV-2 viral genome contains a positive-strand single-stranded RNA of ∼30 kb. Human ACE2 protein is the receptor for SARS-CoV-2 virus attachment and infection. We propose to use ribonucleases (RNases) as antiviral agents to destroy the vira
Externí odkaz:
https://doaj.org/article/a49ee93ac12144d0b2b782c712df862c
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0247541 (2021)
Single-molecule Real-Time (SMRT) sequencing can easily identify sites of N6-methyladenine and N4-methylcytosine within DNA sequences, but similar identification of 5-methylcytosine sites is not as straightforward. In prokaryotic DNA, methylation typi
Externí odkaz:
https://doaj.org/article/2900462d9e0a40dcb80924cc2589c2eb
Autor:
Iain A Murray, Yvette A Luyten, Alexey Fomenkov, Nan Dai, Ivan R Corrêa, William G Farmerie, Tyson A Clark, Jonas Korlach, Richard D Morgan, Richard J Roberts
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253267 (2021)
We report a new subgroup of Type III Restriction-Modification systems that use m4C methylation for host protection. Recognition specificities for six such systems, each recognizing a novel motif, have been determined using single molecule real-time D
Externí odkaz:
https://doaj.org/article/2f77b6fdc04f4e65b94bfac091b7ee0f