Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alexei Yu. Denisov"'
Autor:
Peter S. McPherson, Patrick D. Allaire, Jonathon L. Burman, Alexei Yu. Denisov, Scott Q. Harper, Brigitte Ritter, Valerie Legendre-Guillemin, Beverly L. Davidson, Sébastien Thomas, Kalle Gehring
Publikováno v:
The Journal of Neuroscience. 26:13202-13212
Clathrin-coated vesicles (CCVs) are responsible for the endocytosis of multiple cargo, including synaptic vesicle membranes. We now describe a new CCV protein, termed connecdenn, that contains an N-terminal DENN (differentially expressed in neoplasti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b30c7f926ed5cfe7b3a8880e1db59f
https://doi.org/10.1523/jneurosci.4608-06.2006
https://doi.org/10.1523/jneurosci.4608-06.2006
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 22:1687-1690
We report on the three dimensional structure of an RNA hairpin containing a 2',5'-linked tetraribonucleotide loop, namely, 5'-rGGAC(UUCG)GUCC-3' (where UUCG = U(2'p5')U(2'p5')C(2'p5')G(2'p5')). We show that the 2',5'-linked RNA loop adopts a conforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c66157e3114d8e0930c00983384c094
https://doi.org/10.1081/ncn-120023114
https://doi.org/10.1081/ncn-120023114
Publikováno v:
Journal of the American Chemical Society. 125:11525-11531
We have recently shown that hairpins containing 2',5'-linked RNA loops exhibit superior thermodynamic stability compared to native hairpins comprised of 3',5'-RNA loops [Hannoush, R. N.; Damha, M. J. J. Am. Chem. Soc. 2001, 123, 12368-12374]. A remar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4cb855764304e43a712dc13d98dc21
https://doi.org/10.1021/ja036207k
https://doi.org/10.1021/ja036207k
Autor:
Pierre Beauparlant, Gang Chen, Alexei Yu. Denisov, Abdelkrim Khadir, Giorgio Attardo, Gordon C. Shore, S.R. Murthy Madiraju, Kalle Gehring
Publikováno v:
Journal of Biological Chemistry. 278:21124-21128
The structure of human BCL-w, an anti-apoptotic member of the BCL-2 family, was determined by triple-resonance NMR spectroscopy and molecular modeling. Introduction of a single amino acid substitution (P117V) significantly improved the quality of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de032c3e240384d0598475fcdbd65e2c
https://doi.org/10.1074/jbc.m301798200
https://doi.org/10.1074/jbc.m301798200
Autor:
Peter S. McPherson, Valerie Legendre-Guillemin, Alexei Yu. Denisov, Brigitte Ritter, Patrick D. Allaire, Peter Zylbergold, Jacynthe Philie, Kalle Gehring
AP-2 is a key regulator of the endocytic protein machinery driving clathrin-coated vesicle (CCV) formation. One critical function, mediated primarily by the AP-2 alpha-ear, is the recruitment of accessory proteins. NECAPs are alpha-ear-binding protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4033833b3ff138605577adba87cdde56
https://europepmc.org/articles/PMC2230672/
https://europepmc.org/articles/PMC2230672/
Publikováno v:
Journal of biomolecular NMR. 29(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1827b7af1cbd4337ab6bd2882a57a30
https://pubmed.ncbi.nlm.nih.gov/15213459
https://pubmed.ncbi.nlm.nih.gov/15213459
Two WXXF-based motifs in NECAPs define the specificity of accessory protein binding to AP-1 and AP-2
Autor:
Elaine C Tung, Christophe Deprez, Brigitte Ritter, Peter S. McPherson, Jacynthe Philie, Kalle Gehring, Alexei Yu. Denisov
Publikováno v:
The EMBO journal. 23(19)
The adaptor proteins AP-2 and AP-1/GGAs are essential components of clathrin coats at the plasma membrane and trans-Golgi network, respectively. The adaptors recruit accessory proteins to clathrin-coated pits, which is dependent on the adaptor ear do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02809a1b7a2abf6e1f7ff6ae98b9b2d1
https://pubmed.ncbi.nlm.nih.gov/15359277
https://pubmed.ncbi.nlm.nih.gov/15359277
Autor:
Alexei Yu, Denisov, Murthy S R, Madiraju, Gang, Chen, Abdelkrim, Khadir, Pierre, Beauparlant, Giorgio, Attardo, Gordon C, Shore, Kalle, Gehring
Publikováno v:
The Journal of biological chemistry. 278(23)
The structure of human BCL-w, an anti-apoptotic member of the BCL-2 family, was determined by triple-resonance NMR spectroscopy and molecular modeling. Introduction of a single amino acid substitution (P117V) significantly improved the quality of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c58e17344d0703704e46d21632377361
https://pubmed.ncbi.nlm.nih.gov/12651847
https://pubmed.ncbi.nlm.nih.gov/12651847
Autor:
Masad J. Damha, Anne M. Noronha, Richard T. Pon, Alexei Yu. Denisov, Jean-François Trempe, Kalle Gehring, Christopher J. Wilds
Hybrids of RNA and arabinonucleic acid (ANA) as well as the 2'-fluoro-ANA analog (2'F-ANA) were recently shown to be substrates of the enzyme RNase H. Although RNase H binds to double-stranded RNA, no cleavage occurs with such duplexes. Therefore, kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6568936cdfce9ca97ccfe17f028fa435
https://europepmc.org/articles/PMC60200/
https://europepmc.org/articles/PMC60200/
Autor:
Jean-François Trempe, Christopher J. Wilds, Richard T. Pon, Masad J. Damha, Kalle Gehring, Alexei Yu. Denisov
Publikováno v:
Journal of the American Chemical Society. 123(21)
The first structure of a 2'-deoxy-2'-fluoro-D-arabinose nucleic acid (2'F-ANA)/RNA duplex is presented. We report the structural characterization by NMR spectroscopy of a small hybrid hairpin, r(GGAC)d(TTCG)2'F-a(GTCC), containing a 2'F-ANA/RNA stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c9bb6f2630698f7d9abeba56d9fdcc
https://pubmed.ncbi.nlm.nih.gov/11457316
https://pubmed.ncbi.nlm.nih.gov/11457316