Zobrazeno 1 - 10
of 314
pro vyhledávání: '"Alexei V. Demchenko"'
Autor:
Alessio Romerio, Ana Rita Franco, Melanie Shadrick, Mohammed Monsoor Shaik, Valentina Artusa, Alice Italia, Federico Lami, Alexei V. Demchenko, Francesco Peri
Publikováno v:
ACS Omega, Vol 8, Iss 39, Pp 36412-36417 (2023)
Externí odkaz:
https://doaj.org/article/9ce4d6ac3c704d55ac40b629ad056cae
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Presented herein is a streamlined synthesis of building blocks of a rare sugar D-altrosamine. Also investigated was the glycosylation of different glycosyl acceptors with differentially protected altrosamine donors. High facial stereoselectivity was
Externí odkaz:
https://doaj.org/article/3ad7e08b097447c1b646d63526befb7b
Publikováno v:
Metals, Vol 13, Iss 1, p 78 (2022)
Nanoporous gold (np-Au) has promising applications in therapeutic delivery. The promises arise from its high surface area-to-volume ratio, ease of tuning shape and size, ability to be modified by organic molecules including drugs, and biocompatibilit
Externí odkaz:
https://doaj.org/article/99f905d64dd7438c99111bede9d67b9e
Publikováno v:
Molecules, Vol 27, Iss 21, p 7354 (2022)
Reported herein is a new protocol for glycosidation of alkyl and aryl thioglycosides in the presence of copper(II) bromide. While the activation with CuBr2 alone was proven suitable for reactive glycosyl donors, the activation of less reactive donors
Externí odkaz:
https://doaj.org/article/18b7a0639b4b41cfb64b466bccc401b1
Autor:
Xiao G. Jia, Alexei V. Demchenko
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2028-2048 (2017)
Carbohydrate oligomers remain challenging targets for chemists due to the requirement for elaborate protecting and leaving group manipulations, functionalization, tedious purification, and sophisticated characterization. Achieving high stereocontrol
Externí odkaz:
https://doaj.org/article/1477248bf241420fbe86da0b3534cb72
Publikováno v:
Nanomaterials, Vol 11, Iss 1, p 208 (2021)
Nanoparticles (NPs) have been widely explored for delivering doxorubicin (DOX), an anticancer drug, to minimize cardiotoxicity. However, their efficiency is marred by a necessity to chemically modify DOX, NPs, or both and low deposition of the admini
Externí odkaz:
https://doaj.org/article/4f574ec7504f4b1289e032d1f61cc6bb
Autor:
Laure Guillotin, Zeinab Assaf, Salvatore G. Pistorio, Pierre Lafite, Alexei V. Demchenko, Richard Daniellou
Publikováno v:
Catalysts, Vol 9, Iss 10, p 826 (2019)
Chemoenzymatic synthesis of glycosides relies on efficient glycosyl donor substrates able to react rapidly and efficiently, yet with increased stability towards chemical or enzymatic hydrolysis. In this context, glycosyl thioimidates have previously
Externí odkaz:
https://doaj.org/article/edb6d566eebf4584ba81213bb33e76da
Autor:
Jacqueline A. Hawkins-Salsbury, Archana R. Parameswar, Xuntian Jiang, Paul H. Schlesinger, Ernesto Bongarzone, Daniel S. Ory, Alexei V. Demchenko, Mark S. Sands
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 12, Pp 3303-3311 (2013)
Globoid cell leukodystrophy (GLD) is a neurological disease caused by deficiency of the lysosomal enzyme galactosylceramidase (GALC). In the absence of GALC, the cytotoxic glycosphingolipid, psychosine (psy), accumulates in the nervous system. Psycho
Externí odkaz:
https://doaj.org/article/516d8dd6d7a041388b68ed58eace6044
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 597-605 (2012)
The O-allylphenyl (AP) anomeric moiety was investigated as a new leaving group that can be activated for chemical glycosylation under a variety of conditions, through both direct and remote pathways. Differentiation between the two activation pathway
Externí odkaz:
https://doaj.org/article/35dc5b2a43a54a5eb9d98154195d564c
Autor:
Jay K. Bhattarai, Dharmendra Neupane, Bishal Nepal, Vasilii Mikhaylov, Alexei V. Demchenko, Keith J. Stine
Publikováno v:
Nanomaterials, Vol 8, Iss 3, p 171 (2018)
Nanoporous gold (np-Au), because of its high surface area-to-volume ratio, excellent conductivity, chemical inertness, physical stability, biocompatibility, easily tunable pores, and plasmonic properties, has attracted much interested in the field of
Externí odkaz:
https://doaj.org/article/91df6ba7890b4621b5aff0f44b79e0e3