Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alexei Surguchev"'
Autor:
Andrei Surguchov, Alexei Surguchev
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3241 (2022)
The synucleins are a family of natively unfolded (or intrinsically unstructured) proteins consisting of α-, β-, and γ-synuclein involved in neurodegenerative diseases and cancer. The current number of publications on synucleins has exceeded 16.000
Externí odkaz:
https://doaj.org/article/d94fbf8343844d7fadb274c4740e4dee
Autor:
Michael C. Stankewich, Jun-Ping Bai, Paul R. Stabach, Saaim Khan, Winston J.T. Tan, Alexei Surguchev, Lei Song, Jon S. Morrow, Joseph Santos-Sacchi, Dhasakumar S. Navaratnam
Publikováno v:
Hearing Research. 423:108564
Reports have proposed a putative role for βV spectrin in outer hair cells (OHCs) of the cochlea. In an ongoing investigation of the role of the cytoskeleton in electromotility, we tested mice with a targeted exon deletion of βV spectrin (Spnb5), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f59f0fa4c50f300838be0590e6f17d8
https://doi.org/10.1016/j.heares.2022.108564
https://doi.org/10.1016/j.heares.2022.108564
Publikováno v:
Biomolecules, Vol 11, Iss 624, p 624 (2021)
Biomolecules
Biomolecules
Synucleinopathies are a group of neurodegenerative diseases characterized by the accumulation of α-synuclein aggregates in neurons, nerve fibers or glial cells. Three main types of diseases belong to the synucleinopathies: Parkinson’s disease, dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe4e24e4765c28bf6b23ed4b60fcc61
https://www.mdpi.com/2218-273X/11/5/624
https://www.mdpi.com/2218-273X/11/5/624
Autor:
Alexei Surguchev, Andrei Surguchov
Publikováno v:
Journal of Neuroscience Research. 97:539-542
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a48657e618b719e2d95b802f285613e
https://doi.org/10.1002/jnr.24384
https://doi.org/10.1002/jnr.24384
Autor:
Andrei Surguchov, Alexei Surguchev
Publikováno v:
Brain Sciences
Brain Sciences, Vol 10, Iss 2, p 121 (2020)
Brain Sciences, Vol 10, Iss 2, p 121 (2020)
Identification of genetic markers of a human disease, which is generally sporadic, may become an essential tool for the investigation of its molecular mechanisms. The role of ABCA7 in Alzheimer’s disease (AD) was discovered less than ten years ago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf39d0b088594c8b3e430987b42fccb
https://pubmed.ncbi.nlm.nih.gov/32098344
https://pubmed.ncbi.nlm.nih.gov/32098344
Publikováno v:
Biology
Biology, Vol 8, Iss 2, p 43 (2019)
Biology, Vol 8, Iss 2, p 43 (2019)
The variety of lifespans of different organisms in nature is amazing. Although it is acknowledged that the longevity is determined by a complex interaction between hereditary and environmental factors, many questions about factors defining lifespan r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6117af894c3d28c41c3b3c0cb3850573
https://pubmed.ncbi.nlm.nih.gov/31137746
https://pubmed.ncbi.nlm.nih.gov/31137746
Autor:
Alexei Surguchev, Andrei Surguchov
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
Synuclein family consists of three members, alpha, beta and gamma-synuclein which are thoroughly investigated for almost 30 years, because of their involvement in human diseases. Since the first synuclein discovery in the brain of the electric ray To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f7f833dda01e4026e07c5900a109a9
https://doi.org/10.3389/fnmol.2017.00224
https://doi.org/10.3389/fnmol.2017.00224
Autor:
Andrei Surguchov, Alexei Surguchev
Publikováno v:
Journal of Neurochemistry. 132:619-621
This is an Editorial highlighting the article "Extracellular α-synuclein alters synaptic transmission in rain neurons by perforating the neuronal plasma membrane" by Pacheco and coauthors, in this issue of Journal of Neurochemistry. The authors demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ccb86b7ae6578c9a53a81661e80cf2
https://doi.org/10.1111/jnc.13045
https://doi.org/10.1111/jnc.13045
Publikováno v:
American Journal of Physiology-Cell Physiology. 303:C143-C150
Large conductance (BK) calcium activated potassium channels (Slo) are ubiquitous and implicated in a number of human diseases including hypertension and epilepsy. BK channels consist of a pore forming α-subunit (Slo) and a number of accessory subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d14186bb5b584f4d6b96d94e89bc8e7
https://doi.org/10.1152/ajpcell.00062.2012
https://doi.org/10.1152/ajpcell.00062.2012
Publikováno v:
American Journal of Physiology-Cell Physiology. 302:C766-C780
Large-conductance calcium-activated potassium (BK) channels are ubiquitous and play an important role in a number of diseases. In hair cells of the ear, they play a critical role in electrical tuning, a mechanism of frequency discrimination. These ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36322ee42207e013b44b6cb709cf08a8
https://doi.org/10.1152/ajpcell.00339.2011
https://doi.org/10.1152/ajpcell.00339.2011