Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alexei S. Kazakov"'
Autor:
Alisa A. Vologzhannikova, Polina A. Khorn, Marina P. Shevelyova, Alexei S. Kazakov, Victor I. Emelyanenko, Eugene A. Permyakov, Sergei E. Permyakov
Publikováno v:
Biomolecules, Vol 11, Iss 1, p 66 (2021)
Oncomodulin (Ocm), or parvalbumin β, is an 11–12 kDa Ca2+-binding protein found inside and outside of vertebrate cells, which regulates numerous processes via poorly understood mechanisms. Ocm consists of two active Ca2+-specific domains of the EF
Externí odkaz:
https://doaj.org/article/f7cfefda04854669a8f755de7705d82a
Autor:
Sergey E. Permyakov, Alisa S. Vologzhannikova, Ekaterina L. Nemashkalova, Alexei S. Kazakov, Alexander I. Denesyuk, Konstantin Denessiouk, Viktoriia E. Baksheeva, Andrey A. Zamyatnin, Evgeni Yu. Zernii, Vladimir N. Uversky, Eugene A. Permyakov
Publikováno v:
Molecules, Vol 24, Iss 13, p 2494 (2019)
Recently, we have found that calcium binding proteins of the EF-hand superfamily (i.e., a large family of proteins containing helix-loop-helix calcium binding motif or EF-hand) contain two types of conserved clusters called cluster I (‘black’ clu
Externí odkaz:
https://doaj.org/article/aebbd46b5c74438f8292075676a5a1c4
Autor:
Andrei S. Sokolov, Alexei S. Kazakov, Valery V. Solovyev, Ramis G. Ismailov, Vladimir N. Uversky, Yulia S. Lapteva, Roman V. Mikhailov, Ekaterina V. Pavlova, Iana O. Terletskaya, Ludmila V. Ermolina, Sergei E. Permyakov, Eugene A. Permyakov
Publikováno v:
Molecules, Vol 21, Iss 12, p 1632 (2016)
Interleukin-11 (IL-11) is a multifunctional cytokine implicated in several normal and pathological processes. The decoding of IL-11 function and development of IL-11-targeted drugs dictate the use of laboratory animals and need of the better understa
Externí odkaz:
https://doaj.org/article/5ded3b8c93964163927ffb4183da0ae5
Autor:
Andrey S Sokolov, Oxana V. Galzitskaya, Ekaterina L. Nemashkalova, Eugene A. Permyakov, Alexei S. Kazakov, Ekaterina A. Litus, E.I. Galushko, S.E. Permyakov, Victor V. Marchenkov, Ulyana F. Dzhus
Publikováno v:
Biochemical and Biophysical Research Communications. 510:248-253
Human serum albumin (HSA) serves as a natural depot of amyloid β peptide (Aβ). Improvement of Aβ binding to HSA should impede Alzheimer's disease (AD). We developed a method for quantitation of the interaction between monomeric Aβ40/42 and HSA us
Autor:
Alexei S. Kazakov, Polina Khorn, Alisa A. Vologzhannikova, Eugene A. Permyakov, Vladimir N. Uversky, Sergei E. Permyakov
Publikováno v:
Cell Calcium. 77:1-7
A comparative study of His-tagged and non-tagged rat β-parvalbumin (rWT β-PA), calcium binding protein with the EF-hand calcium binding domains, has been carried out. The attachment of His-tag increases α-helical content and decreases β-sheets an
Autor:
Sergei E. Permyakov, Marina P. Shevelyova, Eugene A. Permyakov, Maria E. Permyakova, Ramis G. Ismailov, Ekaterina A. Litus, Alexei S. Kazakov
Publikováno v:
International Journal of Biological Macromolecules. 108:143-148
S100 proteins are multifunctional (intra/extra)cellular mostly dimeric calcium-binding proteins engaged into numerous diseases. We have found that monomeric recombinant human S100P protein interacts with intact human serum albumin (HSA) in excess of
Autor:
Vladimir N. Uversky, Elena N. Yundina, Sergei E. Permyakov, Maria E. Permyakova, Eugene A. Permyakov, Alexei S. Kazakov
Publikováno v:
Cell calcium. 87
Bovine S100 G (calbindin D9k, small Ca2+-binding protein of the EF-hand superfamily) is considered as a calcium buffer protein; i.e., the binding of Ca2+ practically does not change its general conformation. A set of experimental approaches has been
Autor:
Vladimir N. Uversky, Alexei S. Kazakov, Alexander I. Denesyuk, Andrey A. Zamyatnin, S.E. Permyakov, Ekaterina L. Nemashkalova, Viktoriia E. Baksheeva, Alisa S. Vologzhannikova, Konstantin Denessiouk, Eugene A. Permyakov, Evgeni Yu. Zernii
Publikováno v:
Molecules, Vol 24, Iss 13, p 2494 (2019)
Molecules
Volume 24
Issue 13
Molecules
Volume 24
Issue 13
Recently, we have found that calcium binding proteins of the EF-hand superfamily (i.e., a large family of proteins containing helix-loop-helix calcium binding motif or EF-hand) contain two types of conserved clusters called cluster I (&lsquo
bla
bla
Autor:
Alexander I. Denesyuk, Alexei S. Kazakov, Sergei E. Permyakov, Eugene A. Permyakov, Maria E. Permyakova, Vladimir N. Uversky, Konstantin Denessiouk
Publikováno v:
Cell calcium. 80
Two highly conserved structural motifs observed in members of the EF-hand family of calcium binding proteins. The motifs provide a supporting scaffold for the Ca2+ binding loops and contribute to the hydrophobic core of the EF-hand domain. Each struc
Autor:
Sergei E. Permyakov, Tajib Mirzabekov, Andrei S. Sokolov, Roman Mikhailov, Andrey R. Yakovenko, Alexei S. Kazakov, Ramis G. Ismailov, Eugene A. Permyakov, Ulitin Andrei Borisovich, Solovyev Valery Vladimirovich, Victoria A. Rastrygina
Publikováno v:
Biochemical and Biophysical Research Communications. 468:733-738
Interleukin-11 (IL-11) and S100P are oncoproteins co-expressed in numerous cancers, which might favor their interaction during oncogenesis. We have explored the possibility of this interaction by surface plasmon resonance spectroscopy, intrinsic fluo