Neuro-Cells therapy improves motor outcomes and suppresses inflammation during experimental syndrome of amyotrophic lateral sclerosis in mice

Autor: Klaus-Peter Lesch, Boris W. Kramer, Ekaterina Veniaminova, Anna Gorlova, Andrei Svistunov, Tatyana Strekalova, D. A. Pavlov, Alexei Liundup, Igor Shafarevich, Erik Ch. Wolters, Aleksei Umriukhin, Allan V. Kalueff, Johannes P.J.M. de Munter

Publikováno v: CNS Neuroscience & Therapeutics, 26(5), 504-517. Wiley
CNS Neuroscience & Therapeutics
CNS Neuroscience and Therapeutics

Aims: Mutations in DNA/RNA-binding factor (fused-in-sarcoma) FUS and superoxide dismutase-1 (SOD-1) cause amyotrophic lateral sclerosis (ALS). They were reproduced in SOD-1-G93A (SOD-1) and new FUS[1-359]-transgenic (FUS-tg) mice, where inflammation

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https://cris.maastrichtuniversity.nl/en/publications/2dada5b0-a0d3-43b8-a6ad-5c8eedfc634d