Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexei Lapin"'
Autor:
Holger Perfahl, Helen M Byrne, Tingan Chen, Veronica Estrella, Tomás Alarcón, Alexei Lapin, Robert A Gatenby, Robert J Gillies, Mark C Lloyd, Philip K Maini, Matthias Reuss, Markus R Owen
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e14790 (2011)
We investigate a three-dimensional multiscale model of vascular tumour growth, which couples blood flow, angiogenesis, vascular remodelling, nutrient/growth factor transport, movement of, and interactions between, normal and tumour cells, and nutrien
Externí odkaz:
https://doaj.org/article/7c38252c1ae64071ac049093438893c7
Publikováno v:
Biotechnology Progress. 22:1305-1312
A method is proposed for identification of kinetic parameters when diffusion of substrates is limiting in reactions catalyzed by immobilized enzymes. This method overcomes conventional sequential procedures, which assume immobilization does not affec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829e6147ee8d86fa4ce223ee7baeefb9
https://doi.org/10.1021/bp060062e
https://doi.org/10.1021/bp060062e
Publikováno v:
Chemical Engineering Science. 61:4783-4797
In the present work, an Euler–Lagrange approach has been applied to characterize the behavior of a heterogeneous cell population in a stirred-tank bioreactor with non-ideal mixing. It allows one to describe population behavior as the outcome of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7584742f53be0d3980b12e559292346e
https://doi.org/10.1016/j.ces.2006.03.003
https://doi.org/10.1016/j.ces.2006.03.003
Publikováno v:
Industrial & Engineering Chemistry Research. 43:4647-4656
In the present work, an Euler−Lagrange approach has been applied to characterize the behavior of a heterogeneous cell population in a stirred-tank bioreactor with nonideal mixing. It allows one to ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed77d6b48a8e07382f93a83f8e99e844
https://doi.org/10.1021/ie030786k
https://doi.org/10.1021/ie030786k
Autor:
Robert A. Gatenby, Alexei Lapin, Mark C. Lloyd, Tomás Alarcón, Holger Perfahl, Robert J. Gillies, Markus R. Owen, Veronica Estrella, Matthias Reuss, T. Chen, Helen M. Byrne, Philip K. Maini
Publikováno v:
Micro and Nano Flow Systems for Bioanalysis ISBN: 9781461443759
We present a three-dimensional, multiscale model of vascular tumour growth, which couples nutrient/growth factor transport, blood flow, angiogenesis, vascular remodelling, movement of and interactions between normal and tumour cells, and nutrient-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75cfccfb135314bb32a57fb15b6f34f
https://doi.org/10.1007/978-1-4614-4376-6_3
https://doi.org/10.1007/978-1-4614-4376-6_3
Publikováno v:
BMC Systems Biology
BMC Systems Biology, 5
BMC Systems Biology, Vol 5, Iss 1, p 71 (2011)
BMC Systems Biology, 5
BMC Systems Biology, Vol 5, Iss 1, p 71 (2011)
Background In this paper we apply a novel agent-based simulation method in order to model intracellular reactions in detail. The simulations are performed within a virtual cytoskeleton enriched with further crowding elements, which allows the analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffaf9adc53a586e78165a7ea14c5550
https://pubmed.ncbi.nlm.nih.gov/21569565
https://pubmed.ncbi.nlm.nih.gov/21569565
Publikováno v:
Advances in biochemical engineering/biotechnology. 121
Agent-based models are rigorous tools for simulating the interactions of individual entities, such as organisms or molecules within cells and assessing their effects on the dynamic behavior of the system as a whole. In context with bioprocess and bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8376f8f8d176c6359c1fa5fe25e12e3
https://pubmed.ncbi.nlm.nih.gov/20140659
https://pubmed.ncbi.nlm.nih.gov/20140659
Publikováno v:
Biosystems Engineering II ISBN: 9783642138652
Agent-based models are rigorous tools for simulating the interactions of individual entities, such as organisms or molecules within cells and assessing their effects on the dynamic behavior of the system as a whole. In context with biopro- cess and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e559565402ae1556178cd1b8a996902
https://doi.org/10.1007/10_2009_53
https://doi.org/10.1007/10_2009_53
Publikováno v:
Biophysical journal. 96(12)
The transduction of signals depends on the translocation of signaling molecules to specific targets. Undirected diffusion processes play a key role in the bridging of spaces between different cellular compartments. The diffusion of the molecules is,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfacddd327eaced07690b777a6543072
https://pubmed.ncbi.nlm.nih.gov/19527672
https://pubmed.ncbi.nlm.nih.gov/19527672
Publikováno v:
Biotechnology Progress; Oct2006, Vol. 22 Issue 5, p1305-1312, 8p