Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alexei J, Stuckel"'
Autor:
Alexei J. Stuckel, Shuai Zeng, Zhen Lyu, Wei Zhang, Xu Zhang, Urszula Dougherty, Reba Mustafi, Tripti Khare, Qiong Zhang, Trupti Joshi, Marc Bissonnette, Sharad Khare
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Sprouty4 (SPRY4) has been frequently reported as a tumor suppressor and is therefore downregulated in various cancers. For the first time, we report that SPRY4 is epigenetically upregulated in colorectal cancer (CRC). In this study, we explored DNA m
Externí odkaz:
https://doaj.org/article/01f8717e29a94b0eaa5128dbd992adb5
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2318-2331 (2022)
CXCR4 is involved in many facets of cancer, including being a major player in establishing metastasis. This is in part due to the deregulation of CXCR4, which can be attributed to many genetic and epigenetic mechanisms, including aberrant microRNA–
Externí odkaz:
https://doaj.org/article/ee2dbae64af94adf8ad00e06d8e14eb6
Autor:
Alexei J. Stuckel, Shuai Zeng, Zhen Lyu, Wei Zhang, Xu Zhang, Urszula Dougherty, Reba Mustafi, Qiong Zhang, Trupti Joshi, Marc Bissonnette, Samrat Roy Choudhury, Sharad Khare
Publikováno v:
Cells, Vol 10, Iss 10, p 2632 (2021)
Conventional wisdom is that Sprouty2 (SPRY2), a suppressor of Receptor Tyrosine Kinase (RTK) signaling, functions as a tumor suppressor and is downregulated in many solid tumors. We reported, for the first time, that increased expression of SPRY2 aug
Externí odkaz:
https://doaj.org/article/7fdf92d5c6ff403b94cd6780e8fa8c7c
Autor:
Alexei J, Stuckel, Shuai, Zeng, Zhen, Lyu, Wei, Zhang, Xu, Zhang, Urszula, Dougherty, Reba, Mustafi, Tripti, Khare, Qiong, Zhang, Trupti, Joshi, Marc, Bissonnette, Sharad, Khare
Publikováno v:
Epigenetics. 18
Sprouty4 (SPRY4) has been frequently reported as a tumor suppressor and is therefore downregulated in various cancers. For the first time, we report that SPRY4 is epigenetically upregulated in colorectal cancer (CRC). In this study, we explored DNA m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18686006396d6a88389bafb81cd3f7b3
https://doi.org/10.1080/15592294.2022.2145068
https://doi.org/10.1080/15592294.2022.2145068
Autor:
Sharad Khare, Reba Mustafi, Marc Bissonnette, Shuai Zeng, Xu Zhang, Trupti Joshi, Zhen Lyu, Alexei J. Stuckel, Samrat Roy Choudhury, Urszula Dougherty, Wei Zhang, Qiong Zhang
Publikováno v:
Cells, Vol 10, Iss 2632, p 2632 (2021)
Cells; Volume 10; Issue 10; Pages: 2632
Cells
Cells; Volume 10; Issue 10; Pages: 2632
Cells
Conventional wisdom is that Sprouty2 (SPRY2), a suppressor of Receptor Tyrosine Kinase (RTK) signaling, functions as a tumor suppressor and is downregulated in many solid tumors. We reported, for the first time, that increased expression of SPRY2 aug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11a311ba27d73a6929992b55dd5e66b
https://www.mdpi.com/2073-4409/10/10/2632
https://www.mdpi.com/2073-4409/10/10/2632
Autor:
Xu Zhang, Urszula Dougherty, Wei Zhang, Diana C. West-Szymanski, Shuai Zeng, Qiong Zhang, Tripti Khare, Trupti Joshi, Alexei J. Stuckel, Reba Mustafi, Elsa Perreand, Marc Bissonnette, Sharad Khare
Publikováno v:
Cancers, Vol 12, Iss 3104, p 3104 (2020)
Cancers
Cancers
In colorectal cancer (CRC), upregulation of the C-X-C motif chemokine receptor 4 (CXCR4) is correlated with metastasis and poor prognosis, highlighting the need to further elucidate CXCR4’s regulation in CRC. For the first time, DNA methylation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431a7e434eb3bcce3949edfdf66b4876
https://www.mdpi.com/2072-6694/12/11/3104
https://www.mdpi.com/2072-6694/12/11/3104
Autor:
Alexei J. Stuckel, Saivaroon Gajagowni, Senthil R. Kumar, Yariswamy Manjunath, Eric T. Kimchi, Jussuf T. Kaifi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Exosomes are extracellular vesicles which are released from healthy and tumor cells into blood circulation. Unique biomolecular cargos such as RNA and protein are loaded in these vesicles. These molecules may have biological functions such as signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4034351795c504924a15e1b34b98a861
https://doi.org/10.1038/s41598-020-59523-0
https://doi.org/10.1038/s41598-020-59523-0
Autor:
Shuai Zeng, Tripti Khare, Trupti Joshi, Wei Zhang, Alexei J. Stuckel, Qiong Zhang, Marc Bissonnette, Diana C. West-Szymanski, Elsa Perreand, Urszula Dougherty, Reba Mustafi, Xu Zhang, Sharad Khare
Publikováno v:
Cancers, Vol 12, Iss 3, p 539 (2020)
Cancers
Volume 12
Issue 3
Cancers
Volume 12
Issue 3
In colorectal cancer (CRC), upregulation of the C-X-C motif chemokine receptor 4 (CXCR4) is correlated with metastasis and poor prognosis, highlighting the need to further elucidate CXCR4&rsquo
s regulation in CRC. For the first time, DNA methyl
s regulation in CRC. For the first time, DNA methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f140ba811d4fa0fb7dd76c4d588d745
https://www.mdpi.com/2072-6694/12/3/539
https://www.mdpi.com/2072-6694/12/3/539
Autor:
Sharad Khare, Alexei J. Stuckel
Publikováno v:
Cancer Research. 81:2089-2089
Background: The specific role of Sprouty-2 in colorectal cancer (CRC) as either a tumor suppressor or an oncogene is unclear. This is further obscured by the fact that no known driver mutations of Sprouty-2 have been reported. Therefore, for the firs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c87866037c4aaeffce4e99ee664590d
https://doi.org/10.1158/1538-7445.am2021-2089
https://doi.org/10.1158/1538-7445.am2021-2089
Autor:
Benjamin T Levinson, Kristen H. Taylor, Almamun, Olha Kholod, J. Wade Davis, Gerald L Arthur, Alexei J. Stuckel, Nathan T. Johnson
Publikováno v:
Leukemia & Lymphoma. 58:2156-2164
A complete understanding of the mechanisms involved in the development of pre-B ALL is lacking. In this study, we integrated DNA methylation data and gene expression data to elucidate the impact of aberrant intergenic DNA methylation on gene expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa20a73f38ed24ce9ad9392c497c320b
https://doi.org/10.1080/10428194.2016.1272683
https://doi.org/10.1080/10428194.2016.1272683