Zobrazeno 1 - 10
of 451
pro vyhledávání: '"Alexei GRATCHEV"'
Publikováno v:
Oncology Reviews, Vol 18 (2024)
Emerging research has uncovered the significance of microbiota in carcinogenesis, with specific bacterial infectious agents linked to around 15% of malignant tumors. This review is focused on the resident kidney microbiome, its composition, and alter
Externí odkaz:
https://doaj.org/article/fd6dbcad7c3c41b4b961142d252aa921
Autor:
Olga Kovaleva, Maxim Sorokin, Anastasija Egorova, Anatoly Petrenko, Ksenya Shelekhova, Alexei Gratchev
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Tumor cells communication with tumor associated macrophages is a highly important factor of tumor malignant potential development. For a long time, studies of this interaction were focused on a cytokine- and other soluble factors -mediated processes.
Externí odkaz:
https://doaj.org/article/2c8279c7e5a0447c9a2b55ca1bd43825
Autor:
Olga V. Kovaleva, Polina Podlesnaya, Maxim Sorokin, Valeria Mochalnikova, Vladimir Kataev, Yuriy A. Khlopko, Andrey O. Plotnikov, Ivan S. Stilidi, Nikolay E. Kushlinskii, Alexei Gratchev
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1516 (2022)
The identification of new prognostic markers of renal cell carcinoma (RCC) is an urgent problem in oncourology. To investigate the potential prognostic significance of tumor microbiome and stromal inflammatory markers, we studied a cohort of 66 patie
Externí odkaz:
https://doaj.org/article/1fa75ca5b73e4892b9d04d5a82eb6172
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1215 (2022)
This Special Issue (SI) has collected the most recent publications on the mechanisms that macrophages use to regulate homeostasis and their involvement in the pathogenesis of various non-infectious diseases [...]
Externí odkaz:
https://doaj.org/article/3e87991562334d40b8ceb91e56123c38
Autor:
Olga V. Kovaleva, Madina A. Rashidova, Daria V. Samoilova, Polina A. Podlesnaya, Valeria V. Mochalnikova, Alexei Gratchev
Publikováno v:
Analytical Cellular Pathology, Vol 2020 (2020)
Background. Tumor-associated macrophages (TAMs) and tumor-infiltrating lymphocytes (TILs) contribute significantly to the development of immunosuppressive properties of a tumor. In this study, we performed immunohistochemical analysis of immune cells
Externí odkaz:
https://doaj.org/article/a26a88ecf97e479f804c6a605857b77f
Autor:
Ilja Ovsiy, Vladimir Riabov, Ioannis Manousaridis, Julia Michel, Kondaiah Moganti, Shuiping Yin, Tengfei Liu, Carsten Sticht, Elisabeth Kremmer, Martin C. Harmsen, Sergij Goerdt, Alexei Gratchev, Julia Kzhyshkowska
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Monocytes are actively recruited at sites of chronic inflammation. However, molecular factors involved in this process are not fully elucidated. Here, we show that cytokine IL-4 which is implicated in the development of chronic inflammatory
Externí odkaz:
https://doaj.org/article/1566807a097949bcbd6e85f9268e49ab
Autor:
Olga Kovaleva, Polina Podlesnaya, Madina Rashidova, Daria Samoilova, Anatoly Petrenko, Valeria Mochalnikova, Vladimir Kataev, Yuri Khlopko, Andrey Plotnikov, Alexei Gratchev
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 743 (2021)
Esophageal cancer is one of the most aggressive malignant neoplasms, with low survival rates and limited treatment options. In this study we analyzed the microbiome composition and the phenotype of inflammatory tumor infiltrate in squamous cell carci
Externí odkaz:
https://doaj.org/article/7ba03228f7e54923b5cba8f97973eb37
Autor:
Olga V. Kovaleva, Daniil Romashin, Irina B. Zborovskaya, Mikhail M. Davydov, Murat S. Shogenov, Alexei Gratchev
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Recent research on cancer-associated microbial communities led to the accumulation of data on the interplay between bacteria, immune and tumor cells, the pathways of bacterial induction of carcinogenesis, and its meaningfulness for medicine. Microbia
Externí odkaz:
https://doaj.org/article/e33bf196b9854fba80daf65d02fcf3b3
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 460 (2021)
In this Special Issue of Biomedicines, we have many insightful reviews and research papers on the subject “Macrophages in Health and Non-infectious Disease”, but first; we should discuss briefly the current situation in the field [...]
Externí odkaz:
https://doaj.org/article/5a2c15e8f1584a7da574308bbb55e49c
Autor:
Olga Kovaleva, Polina Podlesnaya, Madina Rashidova, Daria Samoilova, Anatoly Petrenko, Irina Zborovskaya, Valeria Mochalnikova, Vladimir Kataev, Yuri Khlopko, Andrey Plotnikov, Alexei Gratchev
Publikováno v:
Biomedicines, Vol 8, Iss 9, p 349 (2020)
The link between a lung tumor and the lung microbiome is a largely unexplored issue. To investigate the relationship between a lung microbiome and the phenotype of an inflammatory stromal infiltrate, we studied a cohort of 89 patients with non-small
Externí odkaz:
https://doaj.org/article/2eacc511f23e4a03889380f9b4227e5d