Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Alexandru C Stan"'
Autor:
Elizabeth Ruth Plummer, Magdalena Skowronska, Joanne Lewis, Crescens Diane Tiu, Thomas Kaindl, Inti Zlobec, Malte Kleinschmidt, Fatima König, Alexandru C Stan, Felix Bachmann, Heidi Lane, Alexandar Tzankov, Marc Engelhardt, T.R. Jeffry Evans, Juanita Lopez, Stephanie Anderson, Igor Vivanco, Kirk Beebe
Publikováno v:
Journal of Clinical Oncology. 39:3118-3118
3118 Background: EB1, a protein located on the plus-ends of microtubules is involved in microtubule function and has been associated with glioblastoma (GBM) stem-cell-ness and more aggressive disease. Lisavanbulin (BAL101553) is a prodrug of the lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9cb89babfc5ea2875580e12285a9f1
https://doi.org/10.1200/jco.2021.39.15_suppl.3118
https://doi.org/10.1200/jco.2021.39.15_suppl.3118
Autor:
Heidi Lane, Malte Kleinschmidt, Elizabeth Ruth Plummer, Sarah Derby, Fatima König, Crescens Diane Tiu, Patrick Roth, Anna Stansfeld, Felix Bachmann, Noor Md Haris, Alexandru C Stan, Marc Engelhardt, Thomas Kaindl, Juanita Lopez, T.R. Jeffry Evans, Joel R. Eisner, Karine Litherland, Liam Welsh, Thomas Hundsberger, Stephanie Anderson
Publikováno v:
Journal of Clinical Oncology. 39:TPS2068-TPS2068
TPS2068 Background: Lisavanbulin (BAL101553, prodrug of BAL27862) is a novel tumor checkpoint controller that promotes tumor cell death by modulating the spindle assembly checkpoint. BAL27862 is a lipophilic, small molecule (MW 387) shown in rodents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::260b325158d6b96bd5a3e19856017003
https://doi.org/10.1200/jco.2021.39.15_suppl.tps2068
https://doi.org/10.1200/jco.2021.39.15_suppl.tps2068
Publikováno v:
Neuroscience Letters. 486:174-178
Aim of this study was to examine the dipeptide transport of β-Ala-Lys-N(ɛ)-AMCA in the human glioma cell line U373-MG and its potential regulation by diverse hormones and culture media. A mixed glial primary cell culture of the newborn rat served a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3ec60177e06304527662fa87a683c8
https://doi.org/10.1016/j.neulet.2010.09.046
https://doi.org/10.1016/j.neulet.2010.09.046
Autor:
Alexandru C. Stan, Mathias Zimmermann
Publikováno v:
Journal of Neurosurgery. 112:1005-1014
Object The present study was aimed at analyzing the accumulation of the fluorescently tagged dipeptide derivative, β-Ala-Lys-Nε-7-amino-4-methyl coumarin-3-acetic acid (AMCA), in primary cultures of human neoplastic glial cells. This molecule is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b648b5fe9e7826475038748a182c02bd
https://doi.org/10.3171/2009.6.jns08346
https://doi.org/10.3171/2009.6.jns08346
Autor:
Amir Samii, Christian Herold, Karsten H. Wrede, Alexandru C. Stan, Venelin Gerganov, Madjid Samii, Nirjhar Hore
Publikováno v:
Journal of Neurosurgery. 108:803-807
✓Although intracranial metastases of malignant melanomas are common, localization at the cerebellopontine angle (CPA) or in the internal auditory canal (IAC) is rare, and bilateral presentation especially so. We present the case of a 46-year-old Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f71e98b64ea810e06d04b46146d79d1
https://doi.org/10.3171/jns/2008/108/4/0803
https://doi.org/10.3171/jns/2008/108/4/0803
Autor:
Gerrit Paasche, Hubert H. Lim, Thomas Lenarz, Alexandru C. Stan, Günter Reuter, Minoo Lenarz, Nadine Marquardt, Uta Reich, Marc N. Klingberg
Publikováno v:
Otology & Neurotology. 28:1045-1052
Hypothesis Chronic implantation and electric stimulation with a human prototype auditory midbrain implant (AMI) array within the inferior colliculus achieves minimal neuronal damage and does not cause any severe complications. Background An AMI array
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65b19c8df9054ec559c3c9a040817f5
https://doi.org/10.1097/mao.0b013e318159e74f
https://doi.org/10.1097/mao.0b013e318159e74f
Autor:
Jochen Gaedcke, Helmut Ostertag, Frank Traub, Reinhard von Wasielewski, Simone Milde, Alexandru C. Stan, Hans Kreipe, Ludwig Wilkens, Mathias Christgen
Publikováno v:
Modern Pathology. 20:864-870
Although breast cancer is the second most common cause of central nervous system (CNS) metastases with a notable increase of incidence, only few studies on brain-metastasizing breast cancer are available. In this immunohistochemical and fluorescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04e4fb9c386a1edebd1fb997dfc2f23
https://doi.org/10.1038/modpathol.3800830
https://doi.org/10.1038/modpathol.3800830
Publikováno v:
Journal of Medical Case Reports
Introduction A primary intraparenchymal meningioma located in the subcortical region of the brain without a dural attachment is extremely rare. To the best of our knowledge, this is the first report showing that meningioma can mimic cavernous malform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90195b3c40348d9a00ead5127c6433a
https://doi.org/10.1186/1752-1947-8-467
https://doi.org/10.1186/1752-1947-8-467
Publikováno v:
Journal of Autoimmunity. 25:21-32
The self-reactive CD4 T-cells play an essential role in triggering and sustaining organ-specific autoimmune diseases. Silencing or elimination of these cells can prevent and reverse an autoimmune process. We have previously showed that a single dose-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c418e605bd1086f88f5a1a2c6082b5
https://doi.org/10.1016/j.jaut.2005.04.003
https://doi.org/10.1016/j.jaut.2005.04.003
Autor:
Harry Spiera, Constantin A. Bona, Alexandru C. Stan, Tracy L. McGaha, Takao Kodera, Mark Pines
Publikováno v:
Arthritis & Rheumatism. 46:2748-2761
Objective The naturally occurring compound halofuginone has been shown to antagonize collagen synthesis by fibroblasts both in vitro and in vivo. We previously demonstrated that this inhibitory property was related to the ability of halofuginone to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239778705eae52a1f60d76a00727b751
https://doi.org/10.1002/art.10549
https://doi.org/10.1002/art.10549