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pro vyhledávání: '"Alexandrs Gutcaits"'
Autor:
Peteris Prusis, Claes Post, Maris Lapinsh, Jarl E. S. Wikberg, Alexandrs Gutcaits, Torbjörn Lundstedt
Publikováno v:
Protein Science. 11:795-805
We have developed an alignment-independent method for classification of G-protein coupled receptors (GPCRs) according to the principal chemical properties of their amino acid sequences. The method relies on a multivariate approach where the primary a
Publikováno v:
Biochimica et biophysica acta. 1525(1-2)
A novel method for the analysis of drug receptor interactions has been developed and used to explore mechanisms involved in the binding of 4-piperidyl oxazole antagonists to alpha1a-, alpha1b- and alpha1d-adrenoceptors. The method exploits affinity d