Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alexandros Vegiopoulos"'
Dietary calories and lipids synergistically shape adipose tissue cellularity during postnatal growth
Autor:
Irina Meln, Gretchen Wolff, Thomas Gajek, Johanna Koddebusch, Sarah Lerch, Liza Harbrecht, Wujun Hong, Irem Bayindir-Buchhalter, Damir Krunic, Hellmut G. Augustin, Alexandros Vegiopoulos
Publikováno v:
Molecular Metabolism, Vol 24, Iss , Pp 139-148 (2019)
Objective: The susceptibility to abdominal obesity and the metabolic syndrome is determined to a substantial extent during childhood and adolescence, when key adipose tissue characteristics are established. Although the general impact of postnatal nu
Externí odkaz:
https://doaj.org/article/9190b7c0604449e0816ef4588c67fc53
Autor:
Irem Bayindir‐Buchhalter, Gretchen Wolff, Sarah Lerch, Tjeerd Sijmonsma, Maximilian Schuster, Jan Gronych, Adrian T Billeter, Rohollah Babaei, Damir Krunic, Lars Ketscher, Nadine Spielmann, Martin Hrabe de Angelis, Jorge L Ruas, Beat P Müller‐Stich, Mathias Heikenwalder, Peter Lichter, Stephan Herzig, Alexandros Vegiopoulos
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 8, Pp 1-18 (2018)
Abstract Most antidiabetic drugs treat disease symptoms rather than adipose tissue dysfunction as a key pathogenic cause in the metabolic syndrome and type 2 diabetes. Pharmacological targeting of adipose tissue through the nuclear receptor PPARg, as
Externí odkaz:
https://doaj.org/article/a4f7620a706d40c1b743c16d6f4e5f05
Autor:
Didier F. Pisani, Rayane A. Ghandour, Guillaume E. Beranger, Pauline Le Faouder, Jean-Claude Chambard, Maude Giroud, Alexandros Vegiopoulos, Mansour Djedaini, Justine Bertrand-Michel, Michel Tauc, Stephan Herzig, Dominique Langin, Gérard Ailhaud, Christophe Duranton, Ez-Zoubir Amri
Publikováno v:
Molecular Metabolism, Vol 3, Iss 9, Pp 834-847 (2014)
Objective: Brite adipocytes are inducible energy-dissipating cells expressing UCP1 which appear within white adipose tissue of healthy adult individuals. Recruitment of these cells represents a potential strategy to fight obesity and associated disea
Externí odkaz:
https://doaj.org/article/8e7e771460fd48bc8cd10208eb53c7ce
Autor:
Giacomo Volpe, Mary Clarke, Paloma Garcìa, David Scott Walton, Alexandros Vegiopoulos, Walter Del Pozzo, Laura Patricia O'Neill, Jonathan Frampton, Stéphanie Dumon
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138257 (2015)
The MYB transcription factor plays critical roles in normal and malignant haematopoiesis. We previously showed that MYB was a direct activator of FLT3 expression within the context of acute myeloid leukaemia. During normal haematopoiesis, increasing
Externí odkaz:
https://doaj.org/article/e87349e0b90b46529c4aa1f16fccdfd8
Autor:
Karin Mössenböck, Alexandros Vegiopoulos, Adam J Rose, Tjeerd P Sijmonsma, Stephan Herzig, Tobias Schafmeier
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110428 (2014)
Presence of thermogenically active adipose tissue in adult humans has been inversely associated with obesity and type 2 diabetes. While it had been shown that insulin is crucial for the development of classical brown fat, its role in development and
Externí odkaz:
https://doaj.org/article/4f1447626cab45119b840b086d5767e3
Autor:
Dominik Pfister, Moritz Peiseler, Roland Rad, Monika Julia Wolf, Suchira Gallage, Elena Kotsiliti, Caroline L. Wilson, Tjeerd P. Sijmonsma, Nabil Djouder, Marco Prinz, Daniela C. Kroy, Frank Tacke, Jerry Ware, Adnan Ali, Roser Pinyol, Mike Notohamiprodjo, Tracy O'Connor, Christopher J. Weston, Paul Kubes, Bas G.J. Surewaard, Percy A. Knolle, Achim Weber, Michael D. Milsom, Patrick M. Helbling, Daniel Dauch, Tobias Geisler, Mohsen Malehmir, Carsten Deppermann, Alexander Olkus, Marcel Rall, Hellmut G. Augustin, Lars Zender, Julia Volz, Ana Teijeiro, César Nombela-Arrieta, Malte N. Bongers, Valentina Leone, Mathias Heikenwalder, Matthias S. Matter, Dominic J. Withers, Lozan Sheriff, Alexandros Vegiopoulos, Oliver Krenkel, Oliver Borst, Patricia F. Lalor, Jack Leslie, Anahita Rafiei, Florian Baku, David H. Adams, Adam J. Rose, Bernhard Nieswandt, Thomas Engleitner, Hannah K. Drescher, Dominik Rath, Natasha S Anstee, Marlene Kohlhepp, Marc E. Healy, Marta Szydlowska, Meinrad Gawaz, Ruzhica Bogeska, Kristian Unger, Donato Inverso, David Stegner, Martina Hinterleitner, Derek A. Mann, Josep M. Llovet
Publikováno v:
Nature Medicine
Non-alcoholic fatty liver disease ranges from steatosis to non-alcoholic steatohepatitis (NASH), potentially progressing to cirrhosis and hepatocellular carcinoma (HCC). Here, we show that platelet number, platelet activation and platelet aggregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020302d3255a56f374e4d918ceb97c5d
https://doi.org/10.1038/s41591-019-0379-5
https://doi.org/10.1038/s41591-019-0379-5
Autor:
Mohsen Malehmir, Dominik Pfister, Suchira Gallage, Marta Szydlowska, Donato Inverso, Elena Kotsiliti, Valentina Leone, Moritz Peiseler, Bas G. J. Surewaard, Dominik Rath, Adnan Ali, Monika Julia Wolf, Hannah Drescher, Marc E. Healy, Daniel Dauch, Daniela Kroy, Oliver Krenkel, Marlene Kohlhepp, Thomas Engleitner, Alexander Olkus, Tjeerd Sijmonsma, Julia Volz, Carsten Deppermann, David Stegner, Patrick Helbling, César Nombela-Arrieta, Anahita Rafiei, Martina Hinterleitner, Marcel Rall, Florian Baku, Oliver Borst, Caroline L. Wilson, Jack Leslie, Tracy O’Connor, Christopher J. Weston, Abhishek Chauhan, David H. Adams, Lozan Sheriff, Ana Teijeiro, Marco Prinz, Ruzhica Bogeska, Natasha Anstee, Malte N. Bongers, Mike Notohamiprodjo, Tobias Geisler, Dominic J. Withers, Jerry Ware, Derek A. Mann, Hellmut G. Augustin, Alexandros Vegiopoulos, Michael D. Milsom, Adam J. Rose, Patricia F. Lalor, Josep M. Llovet, Roser Pinyol, Frank Tacke, Roland Rad, Matthias Matter, Nabil Djouder, Paul Kubes, Percy A. Knolle, Kristian Unger, Lars Zender, Bernhard Nieswandt, Meinrad Gawaz, Achim Weber, Mathias Heikenwalder
Publikováno v:
Nature Medicine. 28:600-600
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7536524575d9681d9c0e7c53828d271b
https://doi.org/10.1038/s41591-022-01693-7
https://doi.org/10.1038/s41591-022-01693-7
Autor:
Annika Zota, Alexandros Vegiopoulos, Sila Appak-Baskoy, Adriano Maida, Stephan Herzig, Hellmut G. Augustin, Mathias Heikenwalder, Adam J. Rose
Publikováno v:
The Journal of Nutritional Biochemistry. 97:108807
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ac7acdd39aa28166941613995f4ede3
https://doi.org/10.1016/j.jnutbio.2021.108807
https://doi.org/10.1016/j.jnutbio.2021.108807
Autor:
Sabine Schweizer, Sousa Is, Sarah Lerch, Alexandros Vegiopoulos, Martin Klingenspor, Kindler D, Stephan Herzig
Molecular pathways regulating brown adipocyte formation and metabolism can be exploited as targets for the treatment of obesity and disorders of glucose and lipid metabolism such as type-2 diabetes. Investigations in this direction require adequate c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32baceee9c24df42884528c7cf7ca308
https://doi.org/10.1101/565168
https://doi.org/10.1101/565168
Dietary calories and lipids synergistically shape adipose tissue cellularity during postnatal growth
Autor:
Sarah Lerch, Irina Meln, Johanna Koddebusch, Gretchen Wolff, Thomas Gajek, Liza Harbrecht, Hellmut G. Augustin, Alexandros Vegiopoulos, Irem Bayindir-Buchhalter, Damir Krunic, Wujun Hong
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 24, Iss, Pp 139-148 (2019)
Molecular Metabolism, Vol 24, Iss, Pp 139-148 (2019)
Objective The susceptibility to abdominal obesity and the metabolic syndrome is determined to a substantial extent during childhood and adolescence, when key adipose tissue characteristics are established. Although the general impact of postnatal nut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d7e768825532f3fc63406149430920
https://pubmed.ncbi.nlm.nih.gov/31003943
https://pubmed.ncbi.nlm.nih.gov/31003943