Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alexandros Pintzas"'
Autor:
Maria Goulielmaki, Nikos Assimomytis, Jan Rozanc, Eleni Taki, Ioannis Christodoulou, Leonidas G. Alexopoulos, Vassilis Zoumpourlis, Alexandros Pintzas, Demetris Papahatjis
Publikováno v:
Translational Oncology, Vol 12, Iss 7, Pp 932-950 (2019)
Development of novel bioactive compounds against KRAS and/or BRAF mutant colorectal cancer (CRC) is currently an urgent need in oncology. In addition, single or multitarget kinase inhibitors against MEK/ERK and PI3K/AKT pathways are of potential ther
Externí odkaz:
https://doaj.org/article/93d0438a0e504c33b673997ebee46b44
Autor:
Efstathios–Iason Vlachavas, Eleftherios Pilalis, Olga Papadodima, Dirk Koczan, Stefan Willis, Sven Klippel, Caixia Cheng, Leyun Pan, Christos Sachpekidis, Alexandros Pintzas, Vasilis Gregoriou, Antonia Dimitrakopoulou-Strauss, Aristotelis Chatziioannou
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 177-185 (2019)
Purpose: Transcriptomic profiling has enabled the neater genomic characterization of several cancers, among them colorectal cancer (CRC), through the derivation of genes with enhanced causal role and informative gene sets. However, the identification
Externí odkaz:
https://doaj.org/article/446f8b62f1804badb9ee797725a5ef2f
Autor:
Alexandros Pintzas, Sven Klippel, Aristotelis Chatziioannou, Dirk Koczan, Caixia Cheng, Christos Sachpekidis, Vasilis Gregoriou, Stefan Willis, Olga Papadodima, Eleftherios Pilalis, Antonia Dimitrakopoulou-Strauss, Efstathios Iason Vlachavas, Leyun Pan
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 177-185 (2019)
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 177-185 (2019)
Purpose Transcriptomic profiling has enabled the neater genomic characterization of several cancers, among them colorectal cancer (CRC), through the derivation of genes with enhanced causal role and informative gene sets. However, the identification
Autor:
Maria Goulielmaki, Alexandros Pintzas, Nikos Tagmatarchis, Stergios Pispas, Theodosis Skaltsas
Publikováno v:
Journal of materials chemistry. B. 5(27)
Fluorescent carbon quantum dots (CQDs) rich in amine moieties that can be easily protonated under acidic conditions were electrostatically interacted with diblock copolymer poly[sodium(carboxylate sulfamate) isoprene]-b-poly(ethylene oxide) (CSS-IEO-
Autor:
Nikos Assimomytis, Maria Goulielmaki, Alexandros Pintzas, Jan Rozanc, Eleni Taki, Ioannis Christodoulou, Vassilis Zoumpourlis, Demetris Papahatjis, Leonidas G. Alexopoulos
Publikováno v:
Translational Oncology
Translational Oncology, Vol 12, Iss 7, Pp 932-950 (2019)
Translational Oncology, Vol 12, Iss 7, Pp 932-950 (2019)
Development of novel bioactive compounds against KRAS and/or BRAF mutant colorectal cancer (CRC) is currently an urgent need in oncology. In addition, single or multitarget kinase inhibitors against MEK/ERK and PI3K/AKT pathways are of potential ther
Publikováno v:
Journal of Biological Chemistry. 277:7955-7961
CD43 (leukosialin, sialophorin), an abundant leukocyte surface sialoglycoprotein, regulates leukocyte adhesion and transmits activating signals in T cells and dendritic cells. Immobilized anti-CD43 monoclonal antibody (mAb) MEM-59 has been previously
Publikováno v:
Anticancer research. 26(2A)
Novel activating mutations in sporadic colorectal cancer (CRC) have recently been identified on major kinase encoding genes such as BRAF and PI3KCA. The presence of these activating point mutations, including the well characterized KRAS oncogene muta
Autor:
Vassilis Zoumpourlis, Paraskevi Papassava, Alexandros Pintzas, David A. F. Gillespie, Spyros Linardopoulos, Allan Balmain
Publikováno v:
Oncogene 19:35(Aug2000):4011-4021
Analysis of the functions of AP-1 transcription factor in cellular systems has shown its key role as a mediator of oncogenic signals. The employment of suitable animal model systems greatly facilitates the study of changes in the composition and acti