Peripheral blood mononuclear cells extracts VEGF protein levels and VEGF mRNA: Associations with inflammatory molecules in a healthy population.

Autor: Vesna Gorenjak, Dwaine R Vance, Alexandros M Petrelis, Maria G Stathopoulou, Sébastien Dadé, Said El Shamieh, Helena Murray, Christine Masson, John Lamont, Peter Fitzgerald, Sophie Visvikis-Siest

Publikováno v: PLoS ONE, Vol 14, Iss 8, p e0220902 (2019)

BackgroundVascular endothelial growth factor (VEGF) is a signal protein, implicated in various physiological and pathophysiological processes together with other common inflammatory biomarkers. However, their associations have not yet been fully eluc

Externí odkaz: https://doaj.org/article/32d2e2a0b786411e813d786980545abe

The 10th santorini conference: Systems medicine, personalised health and therapy. 'The odyssey from hope to practice: Patient first. Keep Ithaca always in your mind', Santorini, Greece, 23–26 May 2022

Autor: Sophie Visvikis-Siest, Maria G. Stathopoulou, Raute Sunder-Plassmann, Behrooz Z. Alizadeh, Robert Barouki, Ekaterina Chatzaki, Georges Dagher, George Dedoussis, Panagiotis Deloukas, Alexander Haliassos, Brigitte Boisson Hiegel, Vangelis Manolopoulos, Christine Masson, Guillaume Paré, Markus Paulmichl, Alexandros M. Petrelis, Csilla Sipeky, Belgin Süsleyici, Georges Weryha, Alex Chenchik, Paul Diehl, Robin E. Everts, Alexander Haushofer, John Lamont, Ruth Mercado, Heiko Meyer, Herna Munoz-Galeano, Helena Murray, Ferrier Nhat, Charity Nofziger, Wolfgang Schnitzel, Stavroula Kanoni

Publikováno v: Frontiers in Genetics, 14:1171131. Frontiers Media S.A.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1410fba5bf2499e149df6077e4e79fdf
https://hdl.handle.net/11424/288784

Genome-wide association study of circulating interleukin 6 levels identifies novel loci

Autor: Martina Müller-Nurasyid, Jerome I. Rotter, David M. Evans, John P. Kemp, Emelia J. Benjamin, Graciela E. Delgado, Vilmundur Gudnason, Ann Hammarstedt, Panos Deloukas, Aroon D. Hingorani, Riccardo E. Marioni, David Stacey, Jenny van Dongen, Eric Boerwinkle, Joachim Heinrich, Yongmei Liu, S. Goya Wannamethee, Delilah Zabaneh, Braxton D. Mitchell, Marie Standl, Jackie F. Price, Maria G. Stathopoulou, Yoav Ben-Shlomo, Joris Deelen, Eero Kajantie, Mohammadreza Abdollahi, Christie M. Ballantyne, Johan G. Eriksson, Ilkka Seppälä, Elnaz Naderi, Barbara J. Jefferis, Richard W Morris, Nicholas J. Timpson, George Dedoussis, Sirpa Jalkanen, Mika Kivimäki, Perminder S. Sachdev, Diana van Heemst, Melanie Waldenberger, Gaurav Singhal, Elisabeth Thiering, Olli T. Raitakari, Anders Hamsten, Zoltán Kutalik, L. Bain, Eco J. C. de Geus, Tarunveer S. Ahluwalia, Yuri Milaneschi, Hubert Scharnagl, Juan P. Casas, Georg Homuth, Claes Ohlsson, Abbas Dehghan, Nicola J. Armstrong, Behrooz Z. Alizadeh, Terho Lehtimäki, Steve E. Humphries, Naveed Sattar, Bram P. Prins, Peter Rossing, Sophie Visvikis-Siest, Joana A. Revez, Ilja M. Nolte, Stella Trompet, Harold Snieder, Marian Beekman, Diana Marek, Beate St Pourcain, Thorkild I. A. Sørensen, Silvia Naitza, Karen A. Mather, Uwe Völker, Eline Slagboom, Tina Shah, Magdalene C. Jawahar, Jens Baumert, Alexander Teumer, Dorret I. Boomsma, Marcus E. Kleber, Peter Vollenweider, Wolfgang Koenig, Brenda W.J.H. Penninx, Kenneth Rice, Ian J. Deary, Pedro Marques-Vidal, Donna K. Arnett, Eleonora Porcu, Jouke-Jan Hottenga, Maria Sabater-Lleal, Bruce M. Psaty, Matthias Nauck, Dan Mellström, Joel Eriksson, Bernhard T. Baune, Debbie A Lawlor, Catherine Toben, Peter H. Whincup, Toshiko Tanaka, Stavroula Kanoni, Katri Räikkönen, Gonneke Willemsen, Bengt Sennblad, Julian N. Trollor, Yalda Jamshidi, Sarah E. Harris, Jari Lahti, Joshua C. Bis, Peter Durda, Yen Pei C. Chang, Jorgen Engmann, Tom R. Gaunt, Stella Aslibekyan, Anbupalam Thalamuthu, Mary F. Feitosa, Angela Silveira, Tine Jess, Stela McLachlan, J. Wouter Jukema, Chen Lu, Simon P. Mooijaart, Tim D. Spector, Harald Grallert, Winfried März, Alexandros M. Petrelis, Manuel A. R. Ferreira, Meena Kumari

Publikováno v: Human molecular genetics, 30(5), 393-409. Oxford University Press
Human Molecular Genetics, 30(5), 393-409. OXFORD UNIV PRESS
Human Molecular Genetics
Ahluwalia, T S, De Geus, E, Milaneschi, Y, Hottenga, J-J, Van Dongen, J, Willemsen, G, Boomsma, D I, Alizadeh, B Z & CHARGE Inflammation Working Group 2021, ' Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci ', Human molecular genetics, vol. 30, no. 5, pp. 393-409 . https://doi.org/10.1093/hmg/ddab023
Hum Mol Genet
Human Molecular Genetics, 30(5), 393-409. Oxford University Press
Human molecular genetics, vol. 30, no. 5, pp. 393-409
CHARGE Inflammation working group 2021, ' Genome-wide association study of circulating interleukin 6 levels identifies novel loci ', Human Molecular Genetics, vol. 30, no. 5, pp. 393-409 . https://doi.org/10.1093/hmg/ddab023
Human Molecular Genetics, Oxford University Press (OUP), 2021, ⟨10.1093/hmg/ddab023⟩
Hum. Mol. Genet. 30, 393-409 (2021)
Ahluwalia, T S, Prins, B P, Abdollahi, M, Armstrong, N J, Aslibekyan, S, Bain, L, Jefferis, B, Baumert, J, Beekman, M, Ben-shlomo, Y, Bis, J C, Mitchell, B D, De Geus, E, Delgado, G E, Marek, D, Eriksson, J, Kajantie, E, Kanoni, S, Kemp, J P, Lu, C, Marioni, R E, Mclachlan, S, Milaneschi, Y, Nolte, I M, Petrelis, A M, Porcu, E, Sabater-lleal, M, Naderi, E, Seppälä, I, Shah, T, Singhal, G, Standl, M, Teumer, A, Thalamuthu, A, Thiering, E, Trompet, S, Ballantyne, C M, Benjamin, E J, Casas, J P, Toben, C, Dedoussis, G, Deelen, J, Durda, P, Engmann, J, Feitosa, M F, Grallert, H, Hammarstedt, A, Harris, S E, Homuth, G, Hottenga, J, Jalkanen, S, Jamshidi, Y, Jawahar, M C, Jess, T, Kivimaki, M, Kleber, M E, Lahti, J, Liu, Y, Marques-vidal, P, Mellström, D, Mooijaart, S P, Müller-nurasyid, M, Penninx, B, Revez, J A, Rossing, P, Räikkönen, K, Sattar, N, Scharnagl, H, Sennblad, B, Silveira, A, Pourcain, B S, Timpson, N J, Trollor, J, Van Dongen, J, Van Heemst, D, Visvikis-siest, S, Vollenweider, P, Völker, U, Waldenberger, M, Willemsen, G, Zabaneh, D, Morris, R W, Arnett, D K, Baune, B T, Boomsma, D I, Chang, Y C, Deary, I J, Deloukas, P, Eriksson, J G, Evans, D M, Ferreira, M A, Gaunt, T, Gudnason, V, Hamsten, A, Heinrich, J, Hingorani, A, Humphries, S E, Jukema, J W, Koeing, W, Kumari, M, Kutalik, Z, Lawlor, D A, Lehtimäki, T, März, W, Mather, K, Naitza, S, Nauck, M, Ohlsson, C, Price, J F, Raitakari, O, Rice, K, Sachdev, P S, Slagboom, E, Sørensen, T I A, Spector, T, Stacey, D, Stathopoulou, M G, Tanaka, T, Wannamethee, S G, Whincup, P, Rotter, J I, Dehghan, A, Boerwinkle, E, Psaty, B M, Snieder, H & Alizadeh, B Z 2021, ' Genome-wide association study of circulating Interleukin 6 levels identifies novel loci ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddab023
European Journal of Human Genetics, 28(SUPPL 1), 307-308. Nature Publishing Group
Ahluwalia, T S, Prins, B P, Abdollahi, M, Armstrong, N J, Aslibekyan, S, Bain, L, Jefferis, B, Baumert, J, Beekman, M, Ben-Shlomo, Y, Bis, J C, Mitchell, B D, de Geus, E, Delgado, G E, Marek, D, Eriksson, J, Kajantie, E, Kanoni, S, Kemp, J P, Lu, C, Marioni, R E, McLachlan, S, Milaneschi, Y, Nolte, I M, Petrelis, A M, Porcu, E, Sabater-Lleal, M, Naderi, E, Seppälä, I, Shah, T, Singhal, G, Standl, M, Teumer, A, Thalamuthu, A, Thiering, E, Trompet, S, Ballantyne, C M, Benjamin, E J, Casas, J P, Toben, C, Dedoussis, G, Deelen, J, Durda, P, Engmann, J, Feitosa, M F, Grallert, H, Hammarstedt, A, Jess, T, Rossing, P, Sørensen, T I A & CHARGE Inflammation Working Group 2021, ' Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci ', Human Molecular Genetics, vol. 30, no. 5, pp. 393–409 . https://doi.org/10.1093/hmg/ddab023

Interleukin 6 (IL-6) is a multifunctional cytokine with both pro- and anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an increased risk of complex disease patho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175e56e119fa2ad648eb40764e8c6ee2
https://doi.org/10.1093/hmg/ddab023

A transnational collaborative network dedicated to the study and applications of the vascular endothelial growth factor-A in medical practice: the VEGF Consortium

Autor: George Dedoussis, Jochen G. Schneider, Sudha Seshadri, Mary Jo Kurth, Alex Ander Aldasoro Arguinano, Daniela Ruggiero, Georges Dagher, Marina Ciullo, Ting Xie, Vesna Gorenjak, Panagiotis Deloukas, Sophie Visvikis-Siest, Federico Innocenti, Jérôme Chatelin, George Weryha, Janja Marc, Behrooz Z. Alizadeh, John Victor Lamont, Marc Rancier, Maria G. Stathopoulou, Alexandros M. Petrelis, Jean-Louis Merlin, Maurizio Simmaco, Ron H.N. van Schaik

Publikováno v: Clinical chemistry and laboratory medicine, 56(4), E83-E86. Walter de Gruyter GmbH
Clinical Chemistry and Laboratory Medicine
Clinical Chemistry and Laboratory Medicine, De Gruyter, 2018, 56 (4), pp.83-86. ⟨10.1515/cclm-2017-0838⟩
Clinical chemistry and laboratory medicine (2017). doi:10.1515/cclm-2017-0838
info:cnr-pdr/source/autori:Stathopoulou MG, Xie T, Ruggiero D, Chatelin J, Rancier M, Weryha G, Kurth MJ, Aldasoro Arguinano AA, Gorenjak V, Petrelis AM, Dagher G, Dedoussis G, Deloukas P, Lamont J, Marc J, Simmaco M, Schaik RHNV, Innocenti F, Merlin JL, Schneider J, Alizadeh BZ, Ciullo M, Seshadri S, Visvikis-Siest S; VEGF Consortium./titolo:A transnational collaborative network dedicated to the study and applications of the vascular endothelial growth factor-A in medical practice: the VEGF Consortium./doi:10.1515%2Fcclm-2017-0838/rivista:Clinical chemistry and laboratory medicine/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c748e08b98e15811d435eec4fe44f7
https://doi.org/10.1515/cclm-2017-0838

The 9th Santorini Conference: Systems Medicine, Personalised Health and Therapy. 'The Odyssey from Hope to Practice', Santorini, Greece, 30 September–3 October 2018

Autor: Federico Innocenti, Robert Barouki, Lynn Webster, Georges Dagher, Cora Vacher, Christine Masson, Charity Nofziger, Urs A. Meyer, Michael Marschler, Markus Paulmichl, Sophie Visvikis-Siest, Satish Kumar, Georges Weryha, Heiko Meyer, John Victor Lamont, Brigitte Hiegel, Panagiotis Deloukas, Alexandros M. Petrelis, Eric Boerwinkle, Vesna Gorenjak, Maria G. Stathopoulou

Publikováno v: Journal of Personalized Medicine
Journal of Personalized Medicine, MDPI, 2018, 8 (4), pp.43. ⟨10.3390/jpm8040043⟩
Journal of Personalized Medicine, Vol 8, Iss 4, p 43 (2018)

The 9th traditional biannual conference on Systems Medicine, Personalised Health & Therapy—“The Odyssey from Hope to Practice„, inspired by the Greek mythology, was a call to search for practical solutions in cardio-metabolic diseases and cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8d4f7d26cec59cbd3a3cb389711024
https://hal.univ-lorraine.fr/hal-02524735