Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Alexandrina Ferreira Mendes"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 249 (2023)
To explore the molecular mechanisms underlying the anti-inflammatory activity of (R)-(-)-carvone, we evaluated its ability to inhibit the signaling pathways involving the mitogen-activated protein kinases (MAPKs) and the transcription factor, nuclear
Externí odkaz:
https://doaj.org/article/ee24ef4e8e884a888aaf285a85004c61
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 921 (2022)
Sirtuin 1 (SIRT) is a class III, NAD+-dependent histone deacetylase that also modulates the activity of numerous non-histone proteins through deacylation. SIRT1 plays critical roles in regulating and integrating cellular energy metabolism, response t
Externí odkaz:
https://doaj.org/article/05450c6654314b38a808786ed5062233
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 777 (2021)
The signaling pathways involved in age-related inflammation are increasingly recognized as targets for the development of preventive and therapeutic strategies. Our previous study elucidated the structure–activity relationship of monoterpene compou
Externí odkaz:
https://doaj.org/article/a8309c0140c343249ff3c374fb1eeabc
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/62f01d318408456ab16b2e33873d1ee1
Publikováno v:
Journal of Functional Morphology and Kinesiology, Vol 3, Iss 3, Pp 42-0 (2018)
We are glad to introduce the ninth Journal Club. This edition is focused on several relevant studies published in the last few years in the field of Exercise-Induced Immune Response, chosen by our Editorial Board members and their colleagues. We hope
Externí odkaz:
https://doaj.org/article/035ed839c4d540aeaea6559ccf7b3958
Publikováno v:
Frontiers in Physiology, Vol 4 (2013)
Externí odkaz:
https://doaj.org/article/cfb3cf6026e645968f107d48db223a81
Publikováno v:
Journal of Cellular Physiology. 235:8486-8494
Estrogen hormones are important for cartilage homeostasis, but nothing is known regarding the expression and role of the membrane G protein-coupled estrogen receptor (GPER), G protein-coupled receptor 30 (GPR30), in adult articular chondrocytes. Usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c0ae512fb3fea8685a8f2f5add866d
https://doi.org/10.1002/jcp.29691
https://doi.org/10.1002/jcp.29691
Autor:
Gabriela Moço, Cátia Sousa, Ana Capitão, Stephen Scott MacKinnon, Alcino Jorge Leitão, Alexandrina Ferreira Mendes
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2263
Volume 24
Issue 3
Pages: 2263
The chemical modification of natural compounds is a promising strategy to improve their frequently poor bioavailability and low potency. This study aimed at synthesizing chemical derivatives of carvone, a natural monoterpene with anti-inflammatory pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200d589a1b1e07b485958ea2275acd8f
https://doi.org/10.3390/ijms24032263
https://doi.org/10.3390/ijms24032263
Autor:
Cláudia Cavadas, Ana Rita Álvaro, Alexandrina Ferreira Mendes, Cátia Sousa, Laetitia S. Gaspar
Publikováno v:
Pharmacological research. 164
Osteoarthritis (OA) and Obstructive Sleep Apnea (OSA) are two highly prevalent chronic diseases for which effective therapies are urgently needed. Recent epidemiologic studies, although scarce, suggest that the concomitant occurrence of OA and OSA is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3468d22929de7925b95b0ad72be272
https://pubmed.ncbi.nlm.nih.gov/33352231
https://pubmed.ncbi.nlm.nih.gov/33352231
Publikováno v:
Biomedicines
Volume 9
Issue 7
Biomedicines, Vol 9, Iss 777, p 777 (2021)
Volume 9
Issue 7
Biomedicines, Vol 9, Iss 777, p 777 (2021)
The signaling pathways involved in age-related inflammation are increasingly recognized as targets for the development of preventive and therapeutic strategies. Our previous study elucidated the structure–activity relationship of monoterpene compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e794d651c47c8f133a197d7e541e12
https://doi.org/10.3390/biomedicines9070777
https://doi.org/10.3390/biomedicines9070777