Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alexandria Petrusich"'
Autor:
Janet L. Kwiatkowski, Franco Locatelli, Julia Yang, Isabelle Thuret, Alexis A. Thompson, John B. Porter, Richard A. Colvin, Evangelia Yannaki, Martin Sauer, Ashutosh Lal, Adrian J. Thrasher, Dustin Whitney, Suradej Hongeng, Mark C. Walters, Andreas E. Kulozik, John J. Farrell, David H.K. Chui, Alexandria Petrusich
Publikováno v:
Blood. 136:1-3
Introduction We investigated the impact of β-thalassemia genotypes and disease genetic modifiers including HBA and KLF1 genotype and sentinel single-nucleotide polymorphism (SNP) genotypes at 3 major HbF quantitative trait loci (QTL) on clinical out
Autor:
David C. Shyr, Allison Intondi, Matthew H. Porteus, Daniel P. Dever, Alexandria Petrusich, John F. DiPersio, Joshua Lehrer-Graiwer, Patrick J. Leavey, Julie Kanter, Premanjali Lahiri, Alexis A. Thompson
Publikováno v:
Blood. 138:1864-1864
Background Sickle cell disease (SCD) is a recessive monogenic disease caused by a single point mutation in which glutamic acid replaces valine in Codon 6 of the human beta-globin gene (HBB) leading to the production of abnormal globin chains (HbS) th
Autor:
Mark C. Walters, John E.J. Rasko, Gary J. Schiller, Manfred G. Schmidt, Briana Deary, Alexandria Petrusich, Marina Cavazzana, Morris Kletzel, Janet L. Kwiatkowski, Usanarat Anurathapan, Ying Chen, Suradej Hongeng, Alexis A. Thompson, P. Joy Ho, Elliott Vichinsky
Publikováno v:
Blood. 134:4628-4628
Background Patients with transfusion-dependent β-thalassemia (TDT) may experience transfusional iron overload and end-organ damage. While potentially curative, allogeneic hematopoietic stem cell (HSC) transplantation is limited by transplant-related
Autor:
Stany Chrétien, Jean-Sebastien Diana, Mariane de Montalembert, Olivier Hermine, Alexandria Petrusich, Janet L. Kwiatkowski, Catherine Poirot, Sandeep Soni, Christof von Kalle, Felipe Suarez, Laure Caccavelli, David Davidson, Olivier Negre, Thibaud Lefebvre, Emmanuel Payen, Elliott Vichinsky, David T. Teachey, Philippe Leboulch, Jean-Antoine Ribeil, Marina Cavazzana, Fabrice Monpoux, Suradej Hongeng, Gabor Istvan Veres, Mark C. Walters, John E.J. Rasko, Despina Moshous, Philippe Bourget, Michaela Semeraro, Stéphane Blanche, Salima Hacein-Bey-Abina, Alessandra Magnani, Chantal Brouzes, François Lefrère, Corinne Pondarré, Jean-François Meritet, P. Joy Ho, Laura Sandler, Robert W. Ross, Mohammed Asmal, Alexis A. Thompson, Morris Kletzel, Valentine Brousse, Yves Beuzard, Hervé Puy, Usanarat Anurathapan, Elisa Magrin, Gary J. Schiller
Publikováno v:
New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2018, 378 (16), pp.1479-1493. ⟨10.1056/NEJMoa1705342⟩
The New England journal of medicine, vol 378, iss 16
New England Journal of Medicine, Massachusetts Medical Society, 2018, 378 (16), pp.1479-1493. ⟨10.1056/NEJMoa1705342⟩
The New England journal of medicine, vol 378, iss 16
International audience; BACKGROUND Donor availability and transplantation-related risks limit the broad use of allogeneic hematopoietic-cell transplantation in patients with transfusion-dependent beta-thalassemia. After previously establishing that l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e6db8010bebd03bc12d4fc3bf6e82c
https://hal-cnrs.archives-ouvertes.fr/hal-03295931
https://hal-cnrs.archives-ouvertes.fr/hal-03295931
Autor:
Yi Bin Chen, Phoebe Joy Ho, Morris Kletzel, Alexandria Petrusich, M.C. Walters, John E.J. Rasko, Usanarat Anurathapan, M. Schmidt, Philippe Leboulch, Gary J. Schiller, Alexis A. Thompson, B. Deary, M. Cavazzana, E. Vichinsky, S. Hongeng, J.L. Kwiatkowski
Publikováno v:
HemaSphere. 3:22
Autor:
Alexandria Petrusich, Morris Kletzel, Janet L. Kwiatkowski, Suradej Hongeng, Philippe Leboulch, Usanarat Anurathapan, Christof von Kalle, Elliott Vichinsky, Marina Cavazzana, P. Joy Ho, John E.J. Rasko, Mohammed Asmal, Gary J. Schiller, Alexis A. Thompson, Mark C. Walters
Publikováno v:
Cytotherapy. 19:S19
BACKGROUND Allogeneic hematopoietic stem cell (HSC) transplant is potentially curative for patients with β-thalassemia major or, as more broadly defined, transfusion dependent β-thalassemia (TDT). However, HSC transplant is generally restricted to
Autor:
Alexis A. Thompson, John E Rasko, Suradej Hongeng, Janet L. Kwiatkowski, Gary Schiller, Christof von Kalle, Marina Cavazzana, Philippe Leboulch, Alexandria Petrusich, Sandeep Soni, Mark C. Walters
Publikováno v:
Blood. 124:549-549
Background: Hematopoietic stem cell (HSC) gene therapy has the potential to induce globin production and mitigate the need for blood transfusions in β-thalassemia major. Promising early results for 2 subjects with β0/βE -thalassemia major in the o