Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Alexandria Nardone"'
Autor:
Corey Rogers, Dan A. Erkes, Alexandria Nardone, Andrew E. Aplin, Teresa Fernandes-Alnemri, Emad S. Alnemri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Gasdermins mediate lytic cell death by forming pores in the plasma membrane. Here the authors show that gasdermins also permeabilize mitochondrial membrane, thereby facilitating intrinsic apoptosis pathway, downstream of apoptotic (Gasdermin E) and i
Externí odkaz:
https://doaj.org/article/d0672fa10e2747809092d92318838dba
Autor:
Corey, Rogers, Dan A, Erkes, Alexandria, Nardone, Andrew E, Aplin, Teresa, Fernandes-Alnemri, Emad S, Alnemri
Publikováno v:
Nature Communications
Gasdermin E (GSDME/DFNA5) cleavage by caspase-3 liberates the GSDME-N domain, which mediates pyroptosis by forming pores in the plasma membrane. Here we show that GSDME-N also permeabilizes the mitochondrial membrane, releasing cytochrome c and activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0371049dbbeb2930a1a71b419de79155
https://pubmed.ncbi.nlm.nih.gov/30976076
https://pubmed.ncbi.nlm.nih.gov/30976076