Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexandria M. Palaferri Schieber"'
Publikováno v:
Pathogens and disease. 74(9)
Physiological responses that occur during infection are most often thought of in terms of effectors of microbial destruction through the execution of resistance mechanisms, due to a direct action of the microbe, or are maladaptive consequences of hos
Autor:
Alexandria M. Palaferri Schieber, Grischa Y. Chen, Yujung M. Lee, Mathias Leblanc, Janelle S. Ayres, Karina K. Sanchez, Samuel E. Redford, Maxim N. Shokhirev
Publikováno v:
Cell. 175:146-158.e15
Pathogen virulence exists on a continuum. The strategies that drive symptomatic or asymptomatic infections remain largely unknown. We took advantage of the concept of lethal dose 50 (LD50) to ask which component of individual non-genetic variation be
Autor:
Yujung Michelle Lee, Mathias Leblanc, Brett Collins, Janelle S. Ayres, Michael Downes, Alexandria M. Palaferri Schieber, Max W. Chang, Ronald M. Evans
Publikováno v:
Science (New York, N.Y.). 350(6260)
The benefits of Escherichia coli Infection and intestinal damage can trigger severe muscle wasting and loss of fat in mice. How this happens is poorly understood. Palaferri Schieber et al. discovered a protective Escherichia coli strain in their mous
Autor:
Carolyn O’Connor, Daniela Michel, Sheila Rao, Janelle S. Ayres, Alexandria M. Palaferri Schieber, Mathias Leblanc
Publikováno v:
Cell. 168:503-516.e12
Sickness-induced anorexia is a conserved behavior induced during infections. Here, we report that an intestinal pathogen, Salmonella Typhimurium, inhibits anorexia by manipulating the gut-brain axis. Inhibition of inflammasome activation by the S. Ty