Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alexandria Hoffman"'
Autor:
Elisabet Bjanes, Jiarong Zhou, Tariq Qayum, Nishta Krishnan, Raymond H. Zurich, Nitasha D. Menon, Alexandria Hoffman, Ronnie H. Fang, Liangfang Zhang, Victor Nizet
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 2, Pp n/a-n/a (2023)
The highly multidrug‐resistant (MDR) Gram‐negative bacterial pathogen Acinetobacter baumannii is a top global health priority where an effective vaccine can protect susceptible populations and limit resistance acquisition. Outer membrane vesicles
Externí odkaz:
https://doaj.org/article/c0293a1c86874e619966489e8cace1fb
Autor:
Anna Goddi, Alanis Carmona, Liesl Schroedl, Jeremy M. White, Matthew J. Piron, Avelino De Leon, Isabel Casimiro, Alexandria Hoffman, Maria A. Gonzalez Porras, Eric M. Brey, Matthew J. Brady, Ronald N. Cohen
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Obesity affects nearly one billion globally and can lead to life-threatening sequelae. Consequently, there is an urgent need for novel therapeutics. We have previously shown that laminin, alpha 4 (Lama4) knockout in mice leads to resistance to adipos
Externí odkaz:
https://doaj.org/article/f884771f31624ae99b53464449bd54e7
Autor:
Brittney R. Coats, Kelly Q. Schoenfelt, Valéria C. Barbosa-Lorenzi, Eduard Peris, Chang Cui, Alexandria Hoffman, Guolin Zhou, Sully Fernandez, Lijie Zhai, Ben A. Hall, Abigail S. Haka, Ajay M. Shah, Catherine A. Reardon, Matthew J. Brady, Christopher J. Rhodes, Frederick R. Maxfield, Lev Becker
Publikováno v:
Cell Reports, Vol 20, Iss 13, Pp 3149-3161 (2017)
During obesity, adipose tissue macrophages (ATMs) adopt a metabolically activated (MMe) phenotype. However, the functions of MMe macrophages are poorly understood. Here, we combine proteomic and functional methods to demonstrate that, in addition to
Externí odkaz:
https://doaj.org/article/9dd7d9447f5a4879beccbb036e888af5
Autor:
Elisabet Bjanes, Jiarong Zhou, Tariq Qayum, Nishta Krishnan, Raymond H. Zurich, Nitasha D. Menon, Alexandria Hoffman, Ronnie H. Fang, Liangfang Zhang, Victor Nizet
Publikováno v:
Advanced NanoBiomed Research. 3:2200130
Publikováno v:
Essential Aspects of Immunometabolism in Health and Disease ISBN: 9783030866839
Evolution has given rise to a variety of ways to store energy ranging from small intracellular lipid droplets to specialized tissue called adipose, which is composed of adipocytes, endothelial cells, and immune cells. In this chapter we will discuss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb3b4efc8818741205e7a713cf02630f
https://doi.org/10.1007/978-3-030-86684-6_10
https://doi.org/10.1007/978-3-030-86684-6_10
Autor:
Yamuna Krishnan, Natalie Pulliam, Kelly Q. Schoenfelt, Xu Anna Tang, Alexandria Hoffman, Tomas Vaisar, Blake McBeth, Lev Becker, Catherine A. Reardon, Chang Cui, Kasturi Chakraborty, Andrea Ballabio, Swati Kulkarni, Ariane Blank
Activating CD8+ T cells by antigen cross-presentation is remarkably effective at eliminating tumours. Although this function is traditionally attributed to dendritic cells, tumour-associated macrophages (TAMs) can also cross-present antigens. TAMs ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe6a4ac0ec1514206ea830d0c9bd5dc
http://hdl.handle.net/11588/863040
http://hdl.handle.net/11588/863040
Autor:
Hilary A. Kenny, Geoffrey L. Greene, Tomas Vaisar, Lev Becker, Chang Cui, Kasturi Chakraborty, Kelly Q. Schoenfelt, Ya-Fang Chang, Ariane Blank, Alexandria Hoffman, Xu Anna Tang, Ernst Lengyel, Kristen M. Becker, Catherine A. Reardon, Guolin Zhou
Publikováno v:
Cell. 184:3163-3177.e21
Cancer cell genetic variability and similarity to host cells have stymied development of broad anti-cancer therapeutics. Our innate immune system evolved to clear genetically diverse pathogens and limit host toxicity; however, whether/how innate immu
Autor:
Alanis Carmona, Yan Li, Joshua Heiman, Honggang Ye, Jonathan H. Kahn, Alexandria Hoffman, Alexandria M. Bobe, Anthony N. Hollenberg, Anna Goddi, Kelly Q. Schoenfelt, Lev Becker, Aishwarya Sharma, Ronald N. Cohen
Publikováno v:
Endocrinology
The Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT) is a nuclear corepressor, regulating the transcriptional activity of many transcription factors critical for metabolic processes. While the importance of the role of SMRT in the