An oomycete effector subverts host vesicle trafficking to channel starvation-induced autophagy to the pathogen interface

Autor: Pooja Pandey, Alexandre Y Leary, Yasin Tumtas, Zachary Savage, Bayantes Dagvadorj, Cian Duggan, Enoch LH Yuen, Nattapong Sanguankiattichai, Emily Tan, Virendrasinh Khandare, Amber J Connerton, Temur Yunusov, Mathias Madalinski, Federico Gabriel Mirkin, Sebastian Schornack, Yasin Dagdas, Sophien Kamoun, Tolga O Bozkurt

Publikováno v: eLife, Vol 10 (2021)

Eukaryotic cells deploy autophagy to eliminate invading microbes. In turn, pathogens have evolved effector proteins to counteract antimicrobial autophagy. How adapted pathogens co-opt autophagy for their own benefit is poorly understood. The Irish fa

Externí odkaz: https://doaj.org/article/b0509c89ae8e43bda07d2342071e3cef

An oomycete effector subverts host vesicle trafficking to channel starvation-induced autophagy to the pathogen interface

Autor: Yasin Tumtas, Bayantes Dagvadorj, Yasin F. Dagdas, Amber J. Connerton, Pooja Pandey, Alexandre Y Leary, Sophien Kamoun, Mathias Madalinski, Virendrasinh Khandare, Tolga O. Bozkurt, Nattapong Sanguankiattichai, Zachary Savage, Federico Gabriel Mirkin, Cian Duggan, Emily Tan, Enoch Lok Him Yuen, Sebastian Schornack, Temur Yunusov

Publikováno v: eLife, Vol 10 (2021)
eLife

Eukaryotic cells deploy autophagy to eliminate invading microbes. In turn, pathogens have evolved effector proteins to counteract antimicrobial autophagy. How adapted pathogens co-opt autophagy for their own benefit is poorly understood. The Irish fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2190130cb77085a09f265739a3e190
https://ueaeprints.uea.ac.uk/id/eprint/81210/

Chloroplasts alter their morphology and accumulate at the pathogen interface during infection by Phytophthora infestans

Autor: Alexandre Y Leary, Benji C. Bateman, David C. A. Gaboriau, Stanley W. Botchway, Virendrasinh Khandare, Zachary Savage, Imogen Sparkes, Yasin Tumtas, Indranil Pan, Andrew D. Ward, Martin H. Schattat, Tolga O. Bozkurt, Yuxi Liang, Lok Him Yuen, Pooja Pandey, Cian Duggan, María Eugenia Segretin, Alexia Toufexi

Publikováno v: Savage, Z, Duggan, C, Toufexi, A, Pandey, P, Liang, Y, Eugenia Segretin, M, Him Yuen, L, Gaboriau, D C A, Leary, A Y, Tumtas, Y, Khandare, V, Ward, A D, Botchway, S W, Bateman, B C, Pan, I, Schattat, M, Sparkes, I & Bozkurt, T O 2021, ' Chloroplasts alter their morphology and accumulate at the pathogen interface during infection by Phytophthora infestans ', Plant Journal, vol. 107, no. 6, pp. 1771-1787 . https://doi.org/10.1111/tpj.15416
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Consejo Nacional de Investigaciones Científicas y Técnicas
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Upon immune activation, chloroplasts switch off photosynthesis, produce antimicrobial compounds and associate with the nucleus through tubular extensions called stromules. Although it is well established that chloroplasts alter their position in resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64010d10c4e4cb80b04fdfc547b93452
http://hdl.handle.net/10044/1/90860

Dynamic accumulation of a helper NLR at the plant-pathogen interface underpins pathogen recognition

Autor: Chih-Hang Wu, Sophien Kamoun, Hiroaki Adachi, Abbas Maqbool, Yasin Tumtas, Eleonora Moratto, Tolga O. Bozkurt, Zachary Savage, Stephen Rothery, Eranthika Hamilton, Cian Duggan, Alexandre Y Leary, Seda Nohut

Plants employ sensor-helper pairs of NLR immune receptors to recognize pathogen effectors and activate immune responses. Yet the subcellular localization of NLRs pre- and post-activation during pathogen infection remains poorly known. Here we show th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::681e058714241f3bf2f64f53c8bf042e
https://doi.org/10.1101/2021.03.15.435521

Contrasting And Emerging Roles Of Autophagy In Plant Immunity

Autor: Tolga O. Bozkurt, Alexandre Y Leary, Yasin Tumtas, Zachary Savage

Autophagy is a conserved eukaryotic process that mediates degradation and relocation of cellular material to maintain homeostasis and cope with cellular stress. Remarkably, this ancient catabolic machinery has been co-opted to eliminate invading path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e738485ff9e4ec07cd7aab9a69a1ce0f
https://aperta.ulakbim.gov.tr/record/68923