Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Alexandre V Morozov"'
Autor:
Jianneng Yu, Alexandre V Morozov
Publikováno v:
New Journal of Physics, Vol 26, Iss 2, p 023027 (2024)
Many problems in science and technology require finding global minima or maxima of complicated objective functions. The importance of global optimization has inspired the development of numerous heuristic algorithms based on analogies with physical,
Externí odkaz:
https://doaj.org/article/efd0d3d98cce4972ac2ef47cdba000a0
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190186 (2018)
In considering evolution of transcribed regions, regulatory sequences, and other genomic loci, we are often faced with a situation in which the number of allelic states greatly exceeds the size of the population. In this limit, the population eventua
Externí odkaz:
https://doaj.org/article/83a1f5ff7a43412482a9590514cd9dc7
Autor:
Caleb González, Joe Christian J Ray, Michael Manhart, Rhys M Adams, Dmitry Nevozhay, Alexandre V Morozov, Gábor Balázsi
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 8, Pp 1-18 (2015)
Abstract Stress response genes and their regulators form networks that underlie drug resistance. These networks often have an inherent tradeoff: their expression is costly in the absence of stress, but beneficial in stress. They can quickly emerge in
Externí odkaz:
https://doaj.org/article/e7e0704efa474e2d9d4e7fed059a2ef5
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 7, p e1003683 (2014)
Phenotypic states and evolutionary trajectories available to cell populations are ultimately dictated by complex interactions among DNA, RNA, proteins, and other molecular species. Here we study how evolution of gene regulation in a single-cell eukar
Externí odkaz:
https://doaj.org/article/1ea56a01a00a4dfc8b4fa86e7a575782
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 9, p e1002675 (2012)
HIV protease, an aspartyl protease crucial to the life cycle of HIV, is the target of many drug development programs. Though many protease inhibitors are on the market, protease eventually evades these drugs by mutating at a rapid pace and building d
Externí odkaz:
https://doaj.org/article/846fa4e9d31b415590ef98f5aed48f2c
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 10, p e1002224 (2011)
Combinatorial sensor arrays, such as the olfactory system, can detect a large number of analytes using a relatively small number of receptors. However, the complex pattern of receptor responses to even a single analyte, coupled with the non-linearity
Externí odkaz:
https://doaj.org/article/6e419a376bba4f60bee12063306984fa
Publikováno v:
Journal of High Energy Physics, Vol 2023, Iss 2, Pp 1-22 (2023)
Abstract We present a novel computational approach for extracting localized signals from smooth background distributions. We focus on datasets that can be naturally presented as binned integer counts, demonstrating our procedure on the CERN open data
Externí odkaz:
https://doaj.org/article/33e7af43685642f2ab1087ba966a9658
Publikováno v:
Natural Product Reports. 40:766-793
Terpene volatile messengers are widespread among animals. New discoveries have been made about the role and independent evolution of pathways and enzymes in animal terpene biosynthesis, especially in the large group of insects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e318260ff9c04ce3a6ab7dbc0352fbc4
https://doi.org/10.1039/d2np00076h
https://doi.org/10.1039/d2np00076h
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Image-based high-throughput screening (HTS) reveals a high level of heterogeneity in single cells and multiple cellular states may be observed within a single population. Currently available high-dimensional analysis methods are s
Externí odkaz:
https://doaj.org/article/cc4e9232219342d89e8e2ef33729032e
Autor:
Zarley Rebholz, Leena Shewade, Kylie Kaler, Hailey Larose, Florian Schubot, Dorothea Tholl, Alexandre V. Morozov, Paul E. O’Maille
Publikováno v:
Protein Science. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a1ad3d81e1d91f87bf48aff2ecac9d2
https://doi.org/10.1002/pro.4634
https://doi.org/10.1002/pro.4634