Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Alexandre T Fabro"'
Autor:
Keyla S G de Sá, Luana A Amaral, Tamara S Rodrigues, Camila C S Caetano, Amanda Becerra, Sabrina S Batah, Felipe T Lopes, Isadora M de Oliveira, Letícia S Lopes, Leticia Almeida, Caroline M Mota, Samuel Oliveira, Danilo T Wada, Marcel Koenigkam-Santos, Ronaldo B Martins, Roberta R C Rosales, Eurico Arruda, Alexandre T Fabro, Dario S Zamboni
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012222 (2024)
COVID-19 has affected more than half a billion people worldwide, with more than 6.3 million deaths, but the pathophysiological mechanisms involved in lethal cases and the host determinants that determine the different clinical outcomes are still uncl
Externí odkaz:
https://doaj.org/article/eaf6eb7e94f3467683d58b1f62c481e8
Autor:
Ana CG Salina, Douglas dos-Santos, Tamara S Rodrigues, Marlon Fortes-Rocha, Edismauro G Freitas-Filho, Daniel L Alzamora-Terrel, Icaro MS Castro, Thais FC Fraga da Silva, Mikhael HF de Lima, Daniele C Nascimento, Camila M Silva, Juliana E Toller-Kawahisa, Amanda Becerra, Samuel Oliveira, Diego B Caetité, Leticia Almeida, Adriene Y Ishimoto, Thais M Lima, Ronaldo B Martins, Flavio Veras, Natália B do Amaral, Marcela C Giannini, Letícia P Bonjorno, Maria IF Lopes, Maira N Benatti, Sabrina S Batah, Rodrigo C Santana, Fernando C Vilar, Maria A Martins, Rodrigo L Assad, Sergio CL de Almeida, Fabiola R de Oliveira, Eurico Arruda Neto, Thiago M Cunha, José C Alves-Filho, Vania LD Bonato, Fernando Q Cunha, Alexandre T Fabro, Helder I Nakaya, Dario S Zamboni, Paulo Louzada-Junior, Rene DR Oliveira, Larissa D Cunha
Publikováno v:
eLife, Vol 11 (2022)
COVID-19 is a disease of dysfunctional immune responses, but the mechanisms triggering immunopathogenesis are not established. The functional plasticity of macrophages allows this cell type to promote pathogen elimination and inflammation or suppress
Externí odkaz:
https://doaj.org/article/90b9106f59824489a18e93537ba61d8e
Autor:
Sabrina S. Batah, Maíra N. Benatti, Li Siyuan, Wagner M. Telini, Jamile O. Barboza, Marcelo B. Menezes, Tales R. Nadai, Keyla S. G. Sá, Chirag M. Vaswani, Sahil Gupta, Dario S. Zamboni, Danilo T. Wada, Rodrigo T. Calado, Renê D. R. Oliveira, Paulo Louzada‐Junior, Maria Auxiliadora‐Martins, Flávio P. Veras, Larissa D. Cunha, Thiago M. Cunha, Rodrigo Luppino‐Assad, Marcelo L. Balancin, Sirlei S. Morais, Ronaldo B. Martins, Eurico Arruda, Fernando Chahud, Marcel Koenigkam Santos, Andrea A. Cetlin, Fernando Q. Cunha, Claudia dos Santos, Vera L. Capelozzi, Junya Fukuoka, Rosane Duarte Achcar, Alexandre T. Fabro
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 1, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/74cfa39831ad4d07aeb0b2b6fbc99819
Autor:
Flavio P. Veras, Giovanni F. Gomes, Bruna M. S. Silva, Diego B. Caetité, Cicero J. L. R. Almeida, Camila Meirelles S. Silva, Ayda H. Schneider, Emily S. Corneo, Caio S. Bonilha, Sabrina S. Batah, Ronaldo Martins, Eurico Arruda, Alexandre T. Fabro, José C. Alves-Filho, Thiago M. Cunha, Fernando Q. Cunha
Publikováno v:
Respiratory Research. 24
Background COVID-19 is characterized by severe acute lung injury, which is associated with neutrophil infiltration and the release of neutrophil extracellular traps (NETs). COVID-19 treatment options are scarce. Previous work has shown an increase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b8a1bc5364cb39f48de902f346ca8e
https://doi.org/10.1186/s12931-023-02336-2
https://doi.org/10.1186/s12931-023-02336-2
Autor:
Sahil Gupta, Hajera Amatullah, James N. Tsoporis, Kuiru Wei, Ana Paula Teixeira Monteiro, Amin M. Ektesabi, Amir K. Varkouhi, Chirag M. Vaswani, Amanda Formosa, Alexandre T. Fabro, Sri Nagarjun Batchu, Chris Fjell, James A. Russell, Keith R. Walley, Andrew Advani, Thomas G. Parker, John C. Marshall, Patricia R. M. Rocco, Gregory D. Fairn, Tak Wah Mak, Claudia C. dos Santos
Publikováno v:
Cell Death & Differentiation. 29:2024-2033
The ability to effectively clear infection is fundamental to host survival. Sepsis, defined as dysregulated host response to infection, is a heterogenous clinical syndrome that does not uniformly clear intact bacterial or sterile infection (i.e., lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0ffe6c7edb91e1827bdc2f23575e12
https://doi.org/10.1038/s41418-022-00993-2
https://doi.org/10.1038/s41418-022-00993-2
Autor:
Keyla S. G. de Sá, Luana A. Amaral, Tamara S. Rodrigues, Adriene Y. Ishimoto, Warrison A. C. de Andrade, Leticia de Almeida, Felipe Freitas-Castro, Sabrina S. Batah, Sergio C. Oliveira, Mônica T. Pastorello, Alexandre T. Fabro, Dario S. Zamboni
Publikováno v:
Nature Communications. 14
Intracellular parasites from the Leishmania genus cause Leishmaniasis, a disease affecting millions of people worldwide. NLRP3 inflammasome is key for disease outcome, but the molecular mechanisms upstream of the inflammasome activation are still unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1abedfdb051ef04e87ca9ea908afc727
https://doi.org/10.1038/s41467-023-36626-6
https://doi.org/10.1038/s41467-023-36626-6
Autor:
Letícia de Almeida, Alexandre L. N. da Silva, Tamara S. Rodrigues, Samuel Oliveira, Adriene Y. Ishimoto, Amanda A. Seribelli, Amanda Becerra, Warrison A. Andrade, Marco A. Ataide, Camila C. S. Caetano, Keyla S. G. de Sá, Natália Pelisson, Ronaldo B. Martins, Juliano de Paula Souza, Eurico Arruda, Sabrina S. Batah, Ricardo Castro, Fabiani G. Frantz, Fernando Q. Cunha, Thiago M. Cunha, Alexandre T. Fabro, Larissa D. Cunha, Paulo Louzada-Junior, Rene D. R. de Oliveira, Dario S. Zamboni
Publikováno v:
Science advances. 8(37)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces mild or asymptomatic COVID-19 in most cases, but some patients develop an excessive inflammatory process that can be fatal. As the NLRP3 inflammasome and additional inflammasomes ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59753868c38960d9d73dc5ac7153b44
https://pubmed.ncbi.nlm.nih.gov/36103544
https://pubmed.ncbi.nlm.nih.gov/36103544
Autor:
Fernanda Crunfli, Victor C. Carregari, Flavio P. Veras, Lucas S. Silva, Mateus Henrique Nogueira, André Saraiva Leão Marcelo Antunes, Pedro Henrique Vendramini, Aline Gazzola Fragnani Valença, Caroline Brandão-Teles, Giuliana da Silva Zuccoli, Guilherme Reis-de-Oliveira, Lícia C. Silva-Costa, Verônica Monteiro Saia-Cereda, Bradley J. Smith, Ana Campos Codo, Gabriela F de Souza, Stéfanie P. Muraro, Pierina Lorencini Parise, Daniel A. Toledo-Teixeira, Ícaro Maia Santos de Castro, Bruno Marcel Melo, Glaucia M. Almeida, Egidi Mayara Silva Firmino, Isadora Marques Paiva, Bruna Manuella Souza Silva, Rafaela Mano Guimarães, Niele D. Mendes, Raíssa L. Ludwig, Gabriel P. Ruiz, Thiago L. Knittel, Gustavo G. Davanzo, Jaqueline Aline Gerhardt, Patrícia Brito Rodrigues, Julia Forato, Mariene Ribeiro Amorim, Natália S. Brunetti, Matheus Cavalheiro Martini, Maíra Nilson Benatti, Sabrina S. Batah, Li Siyuan, Rafael B. João, Ítalo K. Aventurato, Mariana Rabelo de Brito, Maria J. Mendes, Beatriz A. da Costa, Marina K. M. Alvim, José Roberto da Silva Júnior, Lívia L. Damião, Iêda Maria P. de Sousa, Elessandra D. da Rocha, Solange M. Gonçalves, Luiz H. Lopes da Silva, Vanessa Bettini, Brunno M. Campos, Guilherme Ludwig, Lucas Alves Tavares, Marjorie Cornejo Pontelli, Rosa Maria Mendes Viana, Ronaldo B. Martins, Andre Schwambach Vieira, José Carlos Alves-Filho, Eurico Arruda, Guilherme Gozzoli Podolsky-Gondim, Marcelo Volpon Santos, Luciano Neder, André Damasio, Stevens Rehen, Marco Aurélio Ramirez Vinolo, Carolina Demarchi Munhoz, Paulo Louzada-Junior, Renê Donizeti Oliveira, Fernando Q. Cunha, Helder I. Nakaya, Thais Mauad, Amaro Nunes Duarte-Neto, Luiz Fernando Ferraz da Silva, Marisa Dolhnikoff, Paulo Hilario Nascimento Saldiva, Alessandro S. Farias, Fernando Cendes, Pedro Manoel M. Moraes-Vieira, Alexandre T. Fabro, Adriano Sebollela, José L. Proença-Modena, Clarissa L. Yasuda, Marcelo A. Mori, Thiago M. Cunha, Daniel Martins-de-Souza
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Although increasing evidence confirms neuropsychiatric manifestations associated mainly with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently characterized as part of “long COVID-19” syndrome) has been frequently observ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47ddeff3c7b9a059a857e00fd4d3c15
https://doi.org/10.1073/pnas.2200960119
https://doi.org/10.1073/pnas.2200960119
Autor:
Bruna M. Silva, Flavio P. Veras, Giovanni F. Gomes, Seppe Cambier, Gabriel V. L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camilla M. Silva, Juliana C. Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M. S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C.M. Cebinelli, Naira L. Bibo, Daniel M. Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92d1955374f057b0fde192415d6d085
https://doi.org/10.1101/2022.07.03.498624
https://doi.org/10.1101/2022.07.03.498624
Autor:
Tamara S. Rodrigues, Camila C.S. Caetano, Keyla S.G. de Sá, Leticia Almeida, Amanda Becerra, Augusto V. Gonçalves, Leticia de Sousa Lopes, Samuel Oliveira, Danielle P.A. Mascarenhas, Sabrina S. Batah, Bruna M. Silva, Giovanni F. Gomes, Ricardo Castro, Ronaldo B. Martins, Jonathan Avila, Fabiani G. Frantz, Thiago M. Cunha, Eurico Arruda, Fernando Q Cunha, Helder Nakaya, Larissa D. Cunha, Alexandre T Fabro, Paulo Louzada-Junior, Renê D.R. de Oliveira, Dario S. Zamboni
Infection with SARS-CoV-2 induces COVID-19, an inflammatory disease that is usually self-limited, but depending on patient conditions may culminate with critical illness and patient death. The virus triggers activation of intracellular sensors, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de088ba4aface1ae7c31781704fe04a9
https://doi.org/10.1101/2022.06.29.22277067
https://doi.org/10.1101/2022.06.29.22277067