Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alexandre Sze"'
Autor:
David Olagnier, Alexandre Sze, Samar Bel Hadj, Cindy Chiang, Courtney Steel, Xiaoying Han, Jean-Pierre Routy, Rongtuan Lin, John Hiscott, Julien van Grevenynghe
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004575 (2014)
The mechanisms involved in the persistence of activated CD4+ T lymphocytes following primary human T leukemia/lymphoma virus type 1 (HTLV-1) infection remain unclear. Here, we demonstrate that the HTLV-1 Tax oncoprotein modulates phosphorylation and
Externí odkaz:
https://doaj.org/article/dbc7aea3169c4e23b8f97b7b628bf276
Autor:
Alexandre Sze, David Olagnier, Samar Bel Hadj, Xiaoying Han, Xiao Hong Tian, Hong-Tao Xu, Long Yang, Qingwen Shi, Penghua Wang, Mark A. Wainberg, Jian Hui Wu, Rongtuan Lin
Publikováno v:
Viruses, Vol 9, Iss 10, p 287 (2017)
Flaviviruses including Zika, Dengue and Hepatitis C virus cause debilitating diseases in humans, and the former are emerging as global health concerns with no antiviral treatments. We investigated Sophora Flavecens, used in Chinese medicine, as a sou
Externí odkaz:
https://doaj.org/article/906732291e9c425988c75bbc0a34e75f
Autor:
Yiliu Liu, Samar Bel Hadj, Alexandre Sze, Marie-Line Goulet, Rassin R. Lababidi, Sidi Mehdi Belgnaoui, Rongtuan Lin, Jörg H. Fritz, Chunfu Zheng, David Olagnier
Publikováno v:
Journal of Virology
STING has emerged in recent years as a key player in orchestrating innate immune responses to cytosolic DNA and RNA derived from pathogens. However, the regulation of STING still remains poorly defined. In the present study, we investigated the mecha
Publikováno v:
Sze, A, Olagnier, D, Lin, R, van Grevenynghe, J & Hiscott, J 2013, ' SAMHD1 host restriction factor : a link with innate immune sensing of retrovirus infection ', Journal of Molecular Biology, vol. 425, no. 24, pp. 4981-94 . https://doi.org/10.1016/j.jmb.2013.10.022
SAMHD1 [sterile alpha motif and histidine-aspartic domain (HD) containing protein 1] is the most recent addition to a unique group of host restriction factors that limit retroviral replication at distinct stages of the viral life cycle. SAMHD1 is a d
Autor:
S. Mehdi Belgnaoui, Julien van Grevenynghe, Alexandre Sze, David Olagnier, Rongtuan Lin, John Hiscott
Publikováno v:
Sze, A, Belgnaoui, S M, Olagnier, D, Lin, R, Hiscott, J & van Grevenynghe, J 2013, ' Host restriction factor SAMHD1 limits human T cell leukemia virus type 1 infection of monocytes via STING-mediated apoptosis ', Cell Host & Microbe, vol. 14, no. 4, pp. 422-34 . https://doi.org/10.1016/j.chom.2013.09.009
SummaryHuman T cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T cell leukemia and HTLV-1-associated myelopathies. In addition to T cells, HTLV-1 infects cells of the myeloid lineage, which play critical roles in the host innate r
Autor:
Alexandre Szenicer, Michael Reinwald, Ben Moseley, Tarje Nissen‐Meyer, Zachary Mutinda Muteti, Sandy Oduor, Alex McDermott‐Roberts, Atilim G. Baydin, Beth Mortimer
Publikováno v:
Remote Sensing in Ecology and Conservation, Vol 8, Iss 2, Pp 236-250 (2022)
Abstract We develop a machine learning approach to detect and discriminate elephants from other species, and to recognise important behaviours such as running and rumbling, based only on seismic data generated by the animals. We demonstrate our appro
Externí odkaz:
https://doaj.org/article/bdb407c013b44998bfc940de5c3226f3
Autor:
Jian Hui Wu, Penghua Wang, Hongtao Xu, Long Yang, Samar Bel Hadj, David Olagnier, Xiaoying Han, Alexandre Sze, Mark A. Wainberg, Rongtuan Lin, Qingwen Shi, Xiao Hong Tian
Publikováno v:
Viruses, Vol 9, Iss 10, p 287 (2017)
Viruses
Viruses
Flaviviruses including Zika, Dengue and Hepatitis C virus cause debilitating diseases in humans, and the former are emerging as global health concerns with no antiviral treatments. We investigated Sophora Flavecens, used in Chinese medicine, as a sou
Publikováno v:
Cytokinegrowth factor reviews. 22(4)
Infection with the Human T-cell Leukemia virus type I (HTLV-1) retrovirus results in a number of diverse pathologies, including the aggressive, fatal T-cell malignancy adult T-cell leukemia (ATL) and the chronic, progressive neurologic disorder terme
Autor:
Samar Bel Hadj, Jean-Pierre Routy, Rongtuan Lin, Julien van Grevenynghe, David Olagnier, Courtney Steel, John Hiscott, Cindy Chiang, Xiaoying Han, Alexandre Sze
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004575 (2014)
PLoS Pathogens
PLoS Pathogens
The mechanisms involved in the persistence of activated CD4+ T lymphocytes following primary human T leukemia/lymphoma virus type 1 (HTLV-1) infection remain unclear. Here, we demonstrate that the HTLV-1 Tax oncoprotein modulates phosphorylation and
Publikováno v:
Cytokine. 56:25