Zobrazeno 1 - 10
of 1 620
pro vyhledávání: '"Alexandre PA"'
Autor:
Marco Losa, Marc Emmenegger, Pierre De Rossi, Patrick M Schürch, Tetiana Serdiuk, Niccolò Pengo, Danaëlle Capron, Dimitri Bieli, Niklas Bargenda, Niels J Rupp, Manfredi C Carta, Karl J Frontzek, Veronika Lysenko, Regina R Reimann, Petra Schwarz, Mario Nuvolone, Gunilla T Westermark, K Peter R Nilsson, Magdalini Polymenidou, Alexandre PA Theocharides, Simone Hornemann, Paola Picotti, Adriano Aguzzi
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2024-2042 (2024)
Abstract Extracellularly released molecular inflammasome assemblies -ASC specks- cross-seed Aβ amyloid in Alzheimer’s disease. Here we show that ASC governs the extent of inflammation-induced amyloid A (AA) amyloidosis, a systemic disease caused b
Externí odkaz:
https://doaj.org/article/361701b3ccf5457e8ccf997a37e06f01
Autor:
Jan Mueller, Roman R Schimmer, Christian Koch, Florin Schneiter, Jonas Fullin, Veronika Lysenko, Christian Pellegrino, Nancy Klemm, Norman Russkamp, Renier Myburgh, Laura Volta, Alexandre PA Theocharides, Kari J Kurppa, Benjamin L Ebert, Timm Schroeder, Markus G Manz, Steffen Boettcher
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 445-474 (2024)
Abstract TP53-mutant acute myeloid leukemia (AML) and myelodysplastic neoplasms (MDS) are characterized by chemotherapy resistance and represent an unmet clinical need. Chimeric antigen receptor (CAR) T-cells might be a promising therapeutic option f
Externí odkaz:
https://doaj.org/article/3995291a6c424aeaadea031a81b64f56
Autor:
Beatrice Drexler, Jakob R. Passweg, Alexandar Tzankov, Martin Bigler, Alexandre PA Theocharides, Nathan Cantoni, Peter Keller, Georg Stussi, Axel Ruefer, Rudolf Benz, Geneviève Favre, Pontus Lundberg, Ronny Nienhold, Andrea Fuhrer, Christine Biaggi, Markus G. Manz, Mario Bargetzi, Simon Mendez-Ferrer, Radek C. Skoda
Publikováno v:
Haematologica, Vol 104, Iss 4 (2019)
The β-3 sympathomimetic agonist BRL37344 restored nestin-positive cells within the stem cell niche, and thereby normalized blood counts and improved myelofibrosis in a mouse model of JAK2-V617F-positive myeloproliferative neoplasms. We therefore tes
Externí odkaz:
https://doaj.org/article/8479aa021716446aad1f99447b3fef97
Autor:
Losa, Marco, Emmenegger, Marc, De Rossi, Pierre, Schürch, Patrick M, Serdiuk, Tetiana, Pengo, Niccolò, Capron, Danaëlle, Bieli, Dimitri, Bargenda, Niklas, Rupp, Niels J, Carta, Manfredi C, Frontzek, Karl J, Lysenko, Veronika, Reimann, Regina R, Schwarz, Petra, Nuvolone, Mario, Westermark, Gunilla T, Nilsson, K Peter R, Polymenidou, Magdalini, Theocharides, Alexandre PA
Publikováno v:
EMBO Molecular Medicine; Sep2024, Vol. 16 Issue 9, p2024-2042, 19p
Autor:
Marques-Maggio, Ewerton, Maccio, Umberto, Marx, Alexandra, Galli, Serena, Schwab, Nathalie, Frank, Angela, Hamelin, Baptiste, Varga, Zsuzsanna, Nombela-Arrieta, César, Mertz, Kirsten D, Theocharides, Alexandre Pa, Koelzer, Viktor H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500989d8becf26f62458cb0c6bddb622
https://www.zora.uzh.ch/id/eprint/234183/
https://www.zora.uzh.ch/id/eprint/234183/
Autor:
Marques‐Maggio, Ewerton, Maccio, Umberto, Marx, Alexandra, Galli, Serena, Schwab, Nathalie, Frank, Angela, Hamelin, Baptiste, Varga, Zsuzsanna, Nombela‐Arrieta, César, Mertz, Kirsten D, Theocharides, Alexandre PA, Koelzer, Viktor H
Publikováno v:
Histopathology; Oct2023, Vol. 83 Issue 4, p582-590, 9p
Autor:
Marcelo Hurtado, Leila Khajavi, Abdelmounim Essabbar, Michael Kammer, Ting Xie, Alexis Coullomb, Anne Pradines, Anne Casanova, Anna Kruczynski, Sandrine Gouin, Estelle Clermont, Léa Boutillet, Maria Fernanda Senosain, Yong Zou, Shillin Zhao, Prosper Burq, Abderrahim Mahfoudi, Jerome Besse, Pierre Launay, Alexandre Passioukov, Eric Chetaille, Gilles Favre, Fabien Maldonado, Francisco Cruzalegui, Olivier Delfour, Julien Mazières, Vera Pancaldi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundLung cancer is the leading cause of cancer death worldwide, with poor survival despite recent therapeutic advances. A better understanding of the complexity of the tumor microenvironment is needed to improve patients’ outcome.MethodsWe ap
Externí odkaz:
https://doaj.org/article/714cfc5b4e3645af891ea976e7087685
Autor:
Alexandre Paim Diaz, Andre Braule Pinto, Maria Isabel Chaves Araújo, Rui Mateus Joaquim, Danielle de Souza Costa, Alexandre Luiz de Oliveira Serpa, Anthony R. Pisani, Yeates Conwell, Debora M. Miranda, Leandro F. Malloy-Diniz, Antonio G. da Silva
Publikováno v:
Brazilian Journal of Psychiatry, Vol 46 (2024)
Objective: The risk of suicide is higher among health care workers than other workers. This study investigated the association between social support and suicidal ideation and behavior during the COVID-19 pandemic among Brazilian health care workers.
Externí odkaz:
https://doaj.org/article/cb62f770af3e49c3a5cd6fac68a44a24
Autor:
Sara Cortes-Lara, Paola Medina-Reatiga, Ester del Barrio-Tofiño, María A. Gomis-Font, Gabriel Cabot, Fernando Gómez-Romano, Ignacio Ayestarán, Asunción Colomar, Alexandre Palou-Rotger, Jesús Oteo-Iglesias, Rosa del Campo, Rafael Cantón, Juan P. Horcajada, Carla López-Causapé, Antonio Oliver
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105367- (2024)
Summary: Background: Pseudomonas aeruginosa is a major cause of hospital-acquired and chronic infections, characterised by an extraordinary capacity to develop antimicrobial resistance through the selection of chromosomal mutations, leading to treatm
Externí odkaz:
https://doaj.org/article/26cfb55cfd3a43a1839e0067ff84b55c
Autor:
Jefté Peper-Nascimento, Megan L. Rogers, Alexandre Paim Diaz, Gabriela Serafim Keller, Jenelle A. Richards, Luciane B. Ceretta, Lisa J. Cohen, João Quevedo, Igor Galynker, Samira S. Valvassori
Publikováno v:
Brazilian Journal of Psychiatry, Vol 46 (2024)
Objective: To test the factor structure, reliability, and validity of the Brazilian version of the Abbreviated Suicidal Narrative Inventory (SNI-38). Methods: We used an anonymous online questionnaire of the SNI-38 and self-report measures administer
Externí odkaz:
https://doaj.org/article/5cc00ac710bc417bbbb546f876de7a12