Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexandre P. Cheng"'
Autor:
Ramya Chandrasekaran, Colleen Mathieu, Rishi Sheth, Alexandre P. Cheng, David Fong, Robert McCormack, Hani El-Gabalawy, Suman Alishetty, Mikell Paige, Caroline D. Hoemann
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
UDP-glucose dehydrogenase (UGDH) generates essential precursors of hyaluronic acid (HA) synthesis, however mechanisms regulating its activity are unclear. We used enzyme histostaining and quantitative image analysis to test whether cytokines that sti
Externí odkaz:
https://doaj.org/article/dedddb3ec2f44be299aa315e0cf588fc
Autor:
Philip Burnham, Fanny Chen, Alexandre P. Cheng, Vesh Srivatana, Lisa T. Zhang, Emmanuel Edusei, Shady Albakry, Brittany Botticelli, Xunxi Guo, Amanda Renaghan, Jeffrey Silberzweig, Darshana M. Dadhania, Joan S. Lenz, Michael Heyang, Iliyan D. Iliev, Joshua A. Hayden, Lars F. Westblade, Iwijn De Vlaminck, John R. Lee
Publikováno v:
Kidney Medicine, Vol 4, Iss 1, Pp 100383- (2022)
Rationale & Objective: Conventional culture can be insensitive for the detection of rare infections and for the detection of common infections in the setting of recent antibiotic usage. Patients receiving peritoneal dialysis (PD) with suspected perit
Externí odkaz:
https://doaj.org/article/07991f2dd4e54d8bba497216a3aa2740
Autor:
Liz-Audrey Kounatse Djomnang, Carol Li, Omary Mzava, Alexandre Pellan Cheng, Adrienne Chang, Joan Sesing Lenz, Manikkam Suthanthiran, John R. Lee, Darshana M. Dadhania, Iwijn De Vlaminck
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Urine is a rich source of nucleic acid biomarkers including cell-free DNA (cfDNA) and RNA for monitoring the health of kidney allografts. In this study, we aimed to evaluate whether urine filtration can serve as an alternative to the commonl
Externí odkaz:
https://doaj.org/article/e71c070c37a14af8bdc6327d4a8e55f8
Autor:
Conor J. Loy, Alicia Sotomayor-Gonzalez, Venice Servellita, Jenny Nguyen, Joan Lenz, Sanchita Bhattacharya, Meagan E. Williams, Alexandre P. Cheng, Andrew Bliss, Prachi Saldhi, Noah Brazer, Jessica Streithorst, William Suslovic, Charlotte Hsieh, Burak Bahar, Nathan Wood, Abiodun Foresythe, Amelia Gliwa, Kushmita Bhakta, Maria A. Perez, Laila Hussaini, Evan J. Anderson, Ann Chahroudi, Meghan Delaney, Atul J. Butte, Roberta DeBiasi, Christina A. Rostad, Iwijn De Vlaminck, Charles Y. Chiu
Publikováno v:
Cell reports. Medicine, vol 4, iss 6
SummaryDifferential host responses in coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) remain poorly characterized. Here we use next-generation sequencing to longitudinally analyze blood samples from pedia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd81c4866859e11ed59bc333fc530ab
https://escholarship.org/uc/item/0h23f2gr
https://escholarship.org/uc/item/0h23f2gr
Autor:
Alicia Sotomayor-Gonzalez, Conor J. Loy, Jenny Nguyen, Venice Servellita, Sanchita Bhattacharya, Joan Lenz, Meagan Williams, Will Suslovic, Alexandre P. Cheng, Andrew Bliss, Prachi Saldhi, Jessica Streithorst, Hee Jae Huh, Abiodun Foresythe, Miriam Oseguera, Katrina de la Cruz, Noah Brazer, Nathan Wood, Charlotte Hsieh, Burak Bahar, Amelia Gliwa, Kushmita Bhakta, Maria A. Perez, Evan J. Anderson, Ann Chahroudi, Meghan Delaney, Atul J. Butte, Roberta DeBiasi, Christina A. Rostad, Iwijn De Vlaminck, Charles Chiu
MIS-C is a severe hyperinflammatory condition with involvement of multiple organs that occurs in children who had COVID-19 infection. Accurate diagnostic tests are needed to guide management and appropriate treatment and to inform clinical trials of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88bf9bd84b48489053ef379fb272f0dd
https://doi.org/10.1101/2022.09.26.22280395
https://doi.org/10.1101/2022.09.26.22280395
Autor:
Alexandre P. Cheng, Adam J. Widman, Anushri Arora, Itai Rusinek, William F. Hooper, Rebecca Murray, Daniel Halmos, Theophile Langanay, Giorgio Inghirami, Soren Germer, Melissa Marton, Adrienne Helland, Rob Furatero, Jaime McClintock, Lara Winterkorn, Zoe Steinsnyder, Yohyoh Wang, Srinivas Rajagopalan, Asrar I. Alimohamed, Murtaza S. Malbari, Ashish Saxena, Margaret K. Callahan, Dennie T. Frederick, Lavinia Spain, Ariel Jaimovich, Doron Lipson, Samra Turajlic, Michael C. Zody, Nasser K. Altorki, Jedd D. Wolchok, Michael A. Postow, Nicolas Robine, Genevieve Boland, Dan A. Landau
Publikováno v:
Cancer Research. 83:5709-5709
In many areas of oncology, we lack sensitive tumor-burden monitoring to guide critical decision making. While circulating tumor DNA (ctDNA) promises to enable disease monitoring, this approach is limited by the sparsity of ctDNA in the plasma. To ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c98f0b86ca8d62ee7dfd56cef0dc7694
https://doi.org/10.1158/1538-7445.am2023-5709
https://doi.org/10.1158/1538-7445.am2023-5709
Publikováno v:
The American journal of medicine. 131(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa7dbb32d7a1030f548f2106b0e4975
https://pubmed.ncbi.nlm.nih.gov/29555039
https://pubmed.ncbi.nlm.nih.gov/29555039
Autor:
Omary Mzava, Alexandre Pellan Cheng, Adrienne Chang, Sami Smalling, Liz-Audrey Kounatse Djomnang, Joan Sesing Lenz, Randy Longman, Amy Steadman, Luis G. Gómez-Escobar, Edward J. Schenck, Mirella Salvatore, Michael J. Satlin, Manikkam Suthanthiran, John R. Lee, Christopher E. Mason, Darshana Dadhania, Iwijn De Vlaminck
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The accuracy of metagenomic DNA sequencing is limited by environmental DNA contamination. Here, the authors develop and test SIFT-seq, a metagenomic DNA sequencing assay that allows to identify and remove environmental DNA contamination introduced du
Externí odkaz:
https://doaj.org/article/058d6e9e5ad3482da887a2928dfc0a0a
Autor:
Philip Burnham, Nardhy Gomez-Lopez, Michael Heyang, Alexandre Pellan Cheng, Joan Sesing Lenz, Darshana M. Dadhania, John Richard Lee, Manikkam Suthanthiran, Roberto Romero, Iwijn De Vlaminck
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-9 (2020)
Abstract Background Cell-free DNA (cfDNA) in blood, urine, and other biofluids provides a unique window into human health. A proportion of cfDNA is derived from bacteria and viruses, creating opportunities for the diagnosis of infection via metagenom
Externí odkaz:
https://doaj.org/article/5ab8e5c65f77412299df0844cc927704
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 12, Pp 1-3 (2018)
Abstract Circulating tumor DNA (ctDNA) is a promising diagnostic marker for many cancers and can be noninvasively assayed from blood. For diagnosing glioma, this approach has unfortunately proven to be of limited use since glioma contribute minimal c
Externí odkaz:
https://doaj.org/article/2219ca548b834b2e8489be76740f0d18