Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alexandre P. Blanchard"'
Publikováno v:
Transplantation and Cellular Therapy. 29:131.e1-131.e6
Increasing use of hematopoietic stem cell transplantation (HCT) and improvements in recipient outcomes have led to a steady increase in the number of allogeneic HCT survivors. In addition to complications specific to the transplantation process, HCT
Autor:
Matthew W. Granger, T. Paus, Daniel A. Figeys, Steffany A. L. Bennett, Hongbin Xu, Stephen Fai, Graeme P. Taylor, Zdenka Pausova, Yun Wang, Alexandre P. Blanchard
Bioinformatic tools capable of registering, rapidly and reproducibly, large numbers of nanoliquid chromatography-nanoelectrospray ionization-tandem mass spectrometry (nLC-nESI-MS/MS) lipidomic datasets are lacking. We provide here a freely available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e6436f06061cf1ad1dc3dba89aeba55
https://doi.org/10.1101/2021.05.01.442266
https://doi.org/10.1101/2021.05.01.442266
Autor:
Steffany A. L. Bennett, Hongbin Xu, Alexandre P. Blanchard, Hui Liu, Matthew W. Granger, Caitlin F. Fowler, Samantha P. M. Sherman, Matthew W. Taylor, Weidong Le
Publikováno v:
Journal of Neurochemistry. 149:499-517
Changes in glycerophosphocholine metabolism are observed in Alzheimer's disease; however, it is not known whether these metabolic disruptions are linked to cognitive decline. Here, using unbiased lipidomic approaches and direct biochemical assessment
Autor:
Pierre Villeneuve, Mitchell Sabloff, Sathish Kumar Gopalakrishnan, Natasha Kekre, Lothar Huebsch, Grace Christou, Sita D. Bhella, Mohamad Sobh, David S. Allan, Jill Fulcher, Mike Kennah, Sheryl McDiarmid, Alexandre P. Blanchard, Kelsey Maclellan, Harold L. Atkins, Ranjeeta Mallick, Nicole B. Laferriere, Christopher Bredeson, Sultan Altouri, Elisabeth Drouin
Publikováno v:
Biology of Blood and Marrow Transplantation. 26:S161
Introduction Busulfan (BU) has been used for approximatively four decades as a major component of chemotherapy-based conditioning before allo-HCT. At our center, IV-BU dose in MAC is 12.8 mg/kg (BU12.8) and in those not eligible for MAC, it is 9.6 mg
Autor:
Daniel Figeys, Steffany A. L. Bennett, Stephen Fai, Alexandre P. Blanchard, Graeme P. Taylor, Graeme S. V. McDowell
Publikováno v:
BioMed Research International, Vol 2014 (2014)
BioMed Research International
BioMed Research International
The capacity to predict and visualize all theoretically possible glycerophospholipid molecular identities present in lipidomic datasets is currently limited. To address this issue, we expanded the search-engine and compositional databases of the onli
Autor:
Kelsey Maclellan, Michael Kennah, Sathish Kumar Gopalakrishnan, Harold L. Atkins, Mitchell Sabloff, Sultan Altouri, Mohamad Sobh, Elizabeth Drouin, Lothar Huebsch, Ranjeeta Mallick, David S. Allan, Pierre Villeneuve, Grace Christou, Natasha Kekre, Christopher Bredeson, Jill Fulcher, Alexandre P. Blanchard, Sita D. Bhella, Nicole B. Laferriere
Publikováno v:
Blood. 134:3263-3263
Introduction: With the improvement in transplant practices during recent years, non-relapse mortality (NRM) following allogeneic hematopoietic cell transplantation (allo-HCT) has significantly improved. The use of reduced intensity conditioning has e
Autor:
Leigh Anne Swayne, Maroun Bou Khalil, Steffany A. L. Bennett, Daniel Figeys, Zemin Yao, Weimin Hou, Alexandre P. Blanchard, Hu Zhou, Fred Elisma
Publikováno v:
Mass Spectrometry Reviews. 29:877-929
Lipid mediators participate in signal transduction pathways, proliferation, apoptosis, and membrane trafficking in the cell. Lipids are highly complex and diverse owing to the various combinations of polar headgroups, fatty acyl chains, and backbone
Publikováno v:
Cellular Physiology and Biochemistry. 22:205-214
Background/Aims: The Alzheimer drug memantine (1-amino-3,5-dimethyl-adamantane) blocks the pore channel of the NMDA receptor. Since memantine also blocks the 5-HT 3 receptor, neuronal nicotinic receptor, and voltage-activated Na + channels, the purpo
Autor:
Alexandre P. Blanchard, Robert Dumaine, Pascale K. Lepage, Nancy Francoeur, Simon M. Bousquet, Guylain Boulay, Marc P. Lussier, Hector Barajas-Martinez
Publikováno v:
Journal of Biological Chemistry. 281:30356-30364
Transient receptor potential canonical (TRPC) channels are associated with calcium entry activity in nonexcitable cells. TRPCs can form homo- or heterotetrameric channels, in which case they can assemble together within a subfamily groups. TRPC1, 4,
Autor:
Zhibin Ning, Hongbin Xu, Pierre S. Haddad, Carolina Cieniak, Brian C. Foster, Fida Ahmed, John T. Arnason, Steffany A. L. Bennett, Matthew W. Granger, Alexandre P. Blanchard
Publikováno v:
Alzheimer's & Dementia. 10
SARRACENIA PURPUREA L., ALTERS LEARNING AND MEMORY IN TGCRND8 MICE, LIKELY BY INCREASING LEVELS OF PC(O-16:0/2:0) PAF Carolina Cieniak, Fida Ahmed, Hongbin Xu, Matthew W. Granger, Alexandre P. Blanchard, Zhibin Ning, Pierre S. Haddad, Brian C. Foster