Výsledky vyhledávání - "Alexandre Nadeau"

Abstract 190: Deletion Of Shp-1 Prevents Diabetes-induced Endothelial Cell Senescence And Restores Blood Flow Reperfusion Following Ischemia

Autor: Alexandre Nadeau, Farah Lizotte, Pedro M Geraldes

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 42

Introduction: Ischemia due to narrowing of the femoral artery and distal vessels is also a major cause of peripheral arterial disease and morbidity affecting patients with diabetes. Diabetes-induced premature senescence of endothelial cells has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9d01e430e984eefc9dc653ac3f42408
https://doi.org/10.1161/atvb.42.suppl_1.190

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Endothelial deletion of PKCδ prevents VEGF inhibition and restores blood flow reperfusion in diabetic ischemic limb

Autor: Andréanne Guay, Stéphanie Robillard, Laura Croteau, Clément Mercier, Farah Lizotte, Étienne Fafard-Couture, Valérie Breton, Pedro Geraldes, Alexandre Nadeau, Marc-Antoine Despatis

Publikováno v: Diabetes & Vascular Disease Research

Aims: Peripheral artery disease is a complication of diabetes leading to critical hindlimb ischemia. Diabetes-induced inhibition of VEGF actions is associated with the activation of protein kinase Cδ (PKCδ). We aim to specifically investigate the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c75c804612fdf6c1fe879eb0c6341f
http://europepmc.org/articles/PMC8481738

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