Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Alexandre Mourot"'
Autor:
Jérémie Naudé, Matthieu X. B. Sarazin, Sarah Mondoloni, Bernadette Hannesse, Eléonore Vicq, Fabrice Amegandjin, Alexandre Mourot, Philippe Faure, Bruno Delord
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Phasic variations in dopamine levels are interpreted as a teaching signal reinforcing rewarded behaviors. However, behavior also depends on the motivational, neuromodulatory effect of phasic dopamine. In this study, we reveal a neurodynamica
Externí odkaz:
https://doaj.org/article/2f3ce454957f4aaea8d8879a56438689
Autor:
Lauren M. Reynolds, Aylin Gulmez, Sophie L. Fayad, Renan Costa Campos, Daiana Rigoni, Claire Nguyen, Tinaïg Le Borgne, Thomas Topilko, Domitille Rajot, Clara Franco, Sebastian P. Fernandez, Fabio Marti, Nicolas Heck, Alexandre Mourot, Nicolas Renier, Jacques Barik, Philippe Faure
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract How nicotine acts on developing neurocircuitry in adolescence to promote later addiction vulnerability remains largely unknown, but may hold the key for informing more effective intervention efforts. We found transient nicotine exposure in e
Externí odkaz:
https://doaj.org/article/95c3d968178b496c9ea5ba0da1168e28
Autor:
Mathieu Favier, Elena Martin Garcia, Romain Icick, Camille de Almeida, Joachim Jehl, Mazarine Desplanque, Johannes Zimmermann, Annabelle Henrion, Nina Mansouri-Guilani, Coline Mounier, Svethna Ribeiro, Fiona Henderson, Andrea Geoffroy, Sebastien Mella, Odile Poirel, Véronique Bernard, Véronique Fabre, Yulong Li, Christian Rosenmund, Stéphane Jamain, Florence Vorspan, Alexandre Mourot, Philibert Duriez, Leora Pinhas, Rafael Maldonado, Nicolas Pietrancosta, Stéphanie Daumas, Salah El Mestikawy
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Cholinergic striatal interneurons (ChIs) express the vesicular glutamate transporter 3 (VGLUT3) which allows them to regulate the striatal network with glutamate and acetylcholine (ACh). In addition, VGLUT3-dependent glutamate increases ACh
Externí odkaz:
https://doaj.org/article/92f0421dd9334d49b5771f81a762f0c7
Autor:
Sarah Mondoloni, Claire Nguyen, Eléonore Vicq, Maria Ciscato, Joachim Jehl, Romain Durand-de Cuttoli, Nicolas Torquet, Stefania Tolu, Stéphanie Pons, Uwe Maskos, Fabio Marti, Philippe Faure, Alexandre Mourot
Publikováno v:
eLife, Vol 12 (2023)
Nicotine intake is likely to result from a balance between the rewarding and aversive properties of the drug, yet the individual differences in neural activity that control aversion to nicotine and their adaptation during the addiction process remain
Externí odkaz:
https://doaj.org/article/6cc8bd7aa88147b494aab6baca24e3b1
Autor:
Elise Bousseyrol, Steve Didienne, Samir Takillah, Clement Prevost-Solié, Maxime Come, Tarek Ahmed Yahia, Sarah Mondoloni, Eléonore Vicq, Ludovic Tricoire, Alexandre Mourot, Jérémie Naudé, Philippe Faure
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112523- (2023)
Summary: The neural mechanisms by which animals initiate goal-directed actions, choose between options, or explore opportunities remain unknown. Here, we develop a spatial gambling task in which mice, to obtain intracranial self-stimulation rewards,
Externí odkaz:
https://doaj.org/article/b8abf7cca4e9481fa6034495cc924e38
Autor:
Malou Dongelmans, Romain Durand-de Cuttoli, Claire Nguyen, Maxime Come, Etienne K. Duranté, Damien Lemoine, Raphaël Brito, Tarek Ahmed Yahia, Sarah Mondoloni, Steve Didienne, Elise Bousseyrol, Bernadette Hannesse, Lauren M. Reynolds, Nicolas Torquet, Deniz Dalkara, Fabio Marti, Alexandre Mourot, Jérémie Naudé, Philippe Faure
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Chronic nicotine exposure impacts various components of decision-making processes, such as exploratory behaviors. Here, the authors identify the cellular mechanism and show that chronic nicotine exposure increases the tonic activity of VTA dopaminerg
Externí odkaz:
https://doaj.org/article/ad5caf779392407fa4039e76c1116fb7
Autor:
Damien Lemoine, Sarah Mondoloni, Jérome Tange, Bertrand Lambolez, Philippe Faure, Antoine Taly, Ludovic Tricoire, Alexandre Mourot
Publikováno v:
eLife, Vol 9 (2020)
Glutamate delta (GluD) receptors belong to the ionotropic glutamate receptor family, yet they don’t bind glutamate and are considered orphan. Progress in defining the ion channel function of GluDs in neurons has been hindered by a lack of pharmacol
Externí odkaz:
https://doaj.org/article/0ca7be8901764454b40d9cd49bbd0bb9
Autor:
Romain Durand-de Cuttoli, Sarah Mondoloni, Fabio Marti, Damien Lemoine, Claire Nguyen, Jérémie Naudé, Thibaut d'Izarny-Gargas, Stéphanie Pons, Uwe Maskos, Dirk Trauner, Richard H Kramer, Philippe Faure, Alexandre Mourot
Publikováno v:
eLife, Vol 7 (2018)
Dopamine (DA) neurons of the ventral tegmental area (VTA) integrate cholinergic inputs to regulate key functions such as motivation and goal-directed behaviors. Yet the temporal dynamic range and mechanism of action of acetylcholine (ACh) on the modu
Externí odkaz:
https://doaj.org/article/4f98dc7e2b18434fbd81ab1f8579301b
Autor:
Samir Takillah, Jérémie Naudé, Steve Didienne, Claude Sebban, Brigitte Decros, Esther Schenker, Michael Spedding, Alexandre Mourot, Jean Mariani, Philippe Faure
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Anxiolytic drugs are widely used in the elderly, a population particularly sensitive to stress. Stress, aging and anxiolytics all affect low-frequency oscillations in the hippocampus and prefrontal cortex (PFC) independently, but the interactions bet
Externí odkaz:
https://doaj.org/article/e91bc02558684e47962b9dade8fd4c80
Autor:
Alexandre Mourot
Publikováno v:
médecine/sciences. 39:184-186
Selon Sydney Brenner, lauréat du prix Nobel de physiologie ou médecine en 2002, « les progrès de la science dépendent de nouvelles techniques, de nouvelles découvertes et de nouvelles idées, probablement dans cet ordre ». Le prix Nobel de chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b33a8a680c3a292920efc2960b343c36
https://doi.org/10.1051/medsci/2023010
https://doi.org/10.1051/medsci/2023010