Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alexandre Machado Rubim"'
Autor:
Francine Rodrigues Ianiski, Luciane Varini Laporta, Alexandre Machado Rubim, Cristiane Luchese
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 51, Iss 4, Pp 823-832 (2015)
abstract A method to ensure that an analytical method will produce reliable and interpretable information about the sample must first be validated, making sure that the results can be trusted and traced. In this study, we propose to validate an analy
Externí odkaz:
https://doaj.org/article/66173fa9345947c19b720f0983384efa
Autor:
Alexandre Machado Rubim, Jaqueline Bandeira Rubenick, Eduarda Gregolin, Luciane Varini Laporta, Rosimar Leitenberg, Clarice Madalena Bueno Rolim
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 51, Iss 4, Pp 957-966 (2015)
abstract Amiodarone HCl is an antiarrhythmic agent, which has low aqueous solubility and presents absorption problems. This study aimed to develop inclusion complexes containing hydrophilic carriers PEG 1500, 4000 and 6000 by fusion and kneading meth
Externí odkaz:
https://doaj.org/article/84169ee227c747ab89f1a667c54e2aa5
Autor:
Alexandre Machado Rubim, Jaqueline Bandeira Rubenick, Marcela Maurer, Luciane Varini Laporta, Clarice Madalena Bueno Rolim
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 53, Iss 2 (2017)
ABSTRACT This study aimed to improve the water solubility of amiodarone hydrochloride (AMH) via inclusion complexes with β-cyclodextrin, methyl-β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin. Inclusion complexes were developed by physical mixtu
Externí odkaz:
https://doaj.org/article/23b2997bfae4414a870ac5f4a6824ece
Autor:
Jaqueline Bandeira Rubenick, Alexandre Machado Rubim, Francieli Bellé, Daniele Rubert Nogueira-Librelotto, Clarice Madalena Bueno Rolim
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 53, Iss 1 (2017)
Abstract The purpose of this study was to prepare and characterize mupirocin-loaded polymeric nanocapsules using two different oils and to develop and validate an analytical method for quantitative determination by high performance liquid chromatogra
Externí odkaz:
https://doaj.org/article/e8e42ee487044d88a02178ff3423deb5
Autor:
Alexandre Machado Rubim, Jaqueline Bandeira Rubenick, Luciane Varini Laporta, Clarice Madalena Bueno Rolim
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 50, Iss 2, Pp 423-429 (2014)
The present study describes the development and validation of an in vitro dissolution method for evaluation to release diclofenac potassium in oral suspension. The dissolution test was developed and validated according to international guidelines. Pa
Externí odkaz:
https://doaj.org/article/df1cb04983644fbabfbd4e47cf5b5298
Autor:
Alexandre Machado Rubim, Jaqueline Bandeira Rubenick, Luciane Varine Laporta, Clarice Madalena Bueno Rolim
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 49, Iss 3, Pp 589-597 (2013)
A rapid, simple and low cost method was developed to determine diclofenac potassium (DP) in oral suspension, using a reverse-phase column (C8, 150 mm x 4.6 mm, 5 µm), mobile phase containing methanol/buffer phosphate (70:30 v/v, pH 2.5), at a flow r
Externí odkaz:
https://doaj.org/article/adb9b556057d45819c1a6f88696b9d65
Autor:
Morgana Brondani, Rodrigo de Almeida Vaucher, Virginia Cielo Rech, Jessica Tadiello dos Santos, Éder Maiquel Simão, Ariane Ribas Pohl, Luciane Varini Laporta, Jéssica Dotto de Lara, Vivian S.K. Nishihira, Alexandre Machado Rubim, Michael Gonzalez Durruthy, Christian Masseron Nunes, Jadriane Fontoura Friedrich, Luciane Rosa Feksa
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 61
Nanotechnology has been an important tool for the production of nanoparticles with controlled release of drugs for therapeutic applications. Here, we produced solid lipid nanoparticles (SLN) loaded with curcumin and capsaicin (NCC) following the over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb39cf6953870fef81f3bd84186f0ac
https://pubmed.ncbi.nlm.nih.gov/31299314
https://pubmed.ncbi.nlm.nih.gov/31299314
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences; Vol. 51 No. 4 (2015); 823-832
Brazilian Journal of Pharmaceutical Sciences; Vol. 51 Núm. 4 (2015); 823-832
Brazilian Journal of Pharmaceutical Sciences; v. 51 n. 4 (2015); 823-832
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 51, Iss 4, Pp 823-832 (2015)
Brazilian Journal of Pharmaceutical Sciences, Volume: 51, Issue: 4, Pages: 823-832, Published: DEC 2015
Brazilian Journal of Pharmaceutical Sciences; Vol. 51 Núm. 4 (2015); 823-832
Brazilian Journal of Pharmaceutical Sciences; v. 51 n. 4 (2015); 823-832
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 51, Iss 4, Pp 823-832 (2015)
Brazilian Journal of Pharmaceutical Sciences, Volume: 51, Issue: 4, Pages: 823-832, Published: DEC 2015
A method to ensure that an analytical method will produce reliable and interpretable information about the sample must first be validated, making sure that the results can be trusted and traced. In this study, we propose to validate an analytical hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ce908e2d6a3ce754581831beef415d
https://doi.org/10.1590/s1984-82502015000400008
https://doi.org/10.1590/s1984-82502015000400008
Autor:
Cristiane Luchese, José S. S. Neto, Fernanda D’Avila da Silva, Gilson Zeni, S. C. S. M. Hoelzel, L. V. Laporta, Alexandre Machado Rubim, Francine R. Ianiski
Publikováno v:
Analytical Methods. 7:10409-10413
Organotellurium compounds are important antioxidants, but they are extremely toxic. In order to avoid side effects, nanocarriers can be used to reduce toxicity and increase efficacy in the target cells. Therefore, the aim of this study was to produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fcca66bc62e8ea41f4aa5fba0e41253
https://doi.org/10.1039/c5ay02231b
https://doi.org/10.1039/c5ay02231b
Autor:
Jaqueline Bandeira Rubenick, Clarice Madalena Bueno Rolim, Luciane Varini Laporta, Alexandre Machado Rubim, Marcela Maurer
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 53, Iss 2 (2017)
Brazilian Journal of Pharmaceutical Sciences, Volume: 53, Issue: 2, Article number: e16083, Published: 22 JUN 2017
Brazilian Journal of Pharmaceutical Sciences; Vol. 53 No. 2 (2017); e16083
Brazilian Journal of Pharmaceutical Sciences; Vol. 53 Núm. 2 (2017); e16083
Brazilian Journal of Pharmaceutical Sciences; v. 53 n. 2 (2017); e16083
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Volume: 53, Issue: 2, Article number: e16083, Published: 22 JUN 2017
Brazilian Journal of Pharmaceutical Sciences; Vol. 53 No. 2 (2017); e16083
Brazilian Journal of Pharmaceutical Sciences; Vol. 53 Núm. 2 (2017); e16083
Brazilian Journal of Pharmaceutical Sciences; v. 53 n. 2 (2017); e16083
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
This study aimed to improve the water solubility of amiodarone hydrochloride (AMH) via inclusion complexes with β-cyclodextrin, methyl-β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin. Inclusion complexes were developed by physical mixture, coeva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2be042c0b1bc4b7f52e29094041058
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200607&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200607&lng=en&tlng=en