Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Alexandre M J, Gomila"'
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Akademický článek
Phosphorylation disrupts long-distance electron transport in cytochrome c
Autor: Alexandre M. J. Gomila, Gonzalo Pérez-Mejías, Alba Nin-Hill, Alejandra Guerra-Castellano, Laura Casas-Ferrer, Sthefany Ortiz-Tescari, Antonio Díaz-Quintana, Josep Samitier, Carme Rovira, Miguel A. De la Rosa, Irene Díaz-Moreno, Pau Gorostiza, Marina I. Giannotti, Anna Lagunas
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Electron transfer between mitochondrial cytochrome c and subunit of cytochrome bc 1 can proceed at long distance. Here the authors investigate further the mechanism and show phosphorylation regulation of the interactions between the protein partners
Externí odkaz: https://doaj.org/article/920316e566aa4c3caedde8b39a1e3048
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2
Adrenergic Modulation With Photochromic Ligands
Autor: Pau Gorostiza, Gemma Sangüesa, Alexandre M. J. Gomila, Rebeca Diez-Alarcia, Ernest Giralt, Laura Ramírez, J. Javier Meana, B. Preda, Eduard Guasch, Davia Prischich, Carlo Matera, Montserrat Batlle, Santiago Milla-Navarro, Pedro de la Villa, Jordi Hernando
Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
UnpayWall
ORCID
Archivio Istituzionale della Ricerca dell'Università degli Studi di Milano
Microsoft Academic Graph
Diposit Digital de la Universitat de Barcelona
Altres ajuts: CERCA Programme/Generalitat de Catalunya, Fundaluce and "la Caixa" foundations (ID 100010434, agreement LCF/PR/HR19/52160010), Co-financed by the European Union Regional Development Fund within the framework of the ERDF Operational Prog
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8d2b4dbc224b36ab4878632d7e5a54
http://hdl.handle.net/2445/183210
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3
Reversible photocontrol of dopaminergic transmission in wild-type animals
Autor: Carlo Matera, Pablo Calvé, Verònica Casadó-Anguera, Rosalba Sortino, Alexandre M. J. Gomila, Estefanía Moreno, Thomas Gener, Cristina Delgado-Sallent, Pau Nebot, Davide Costazza, Sara Conde-Berriozabal, Mercè Masana, Jordi Hernando, Vicent Casadó, M. Victoria Puig, Pau Gorostiza
Publikováno v: ORCID
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 10114
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Understanding the dopaminergic system is a priority in neurobiology and neuropharmacology. Dopamine receptors are involved in the modulation of fundamental physiological functions, and dysregulation of dopaminergic transmission is associated with maj
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921d906e8fe6bf668fc1abf5545eb3ce
https://doi.org/10.26434/chemrxiv-2022-8jlxp
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4
Subunit-specific photocontrol of glycine receptors by azobenzene-nitrazepam photoswitcher
Autor: Piotr Bregestovski, Daniel Wutz, Mercedes Alfonso-Prieto, Alexandre M. J. Gomila, Elena Petukhova, Daria Ponomareva, Alba Nin-Hill, Elvira Mukhametova, Galyna Maleeva, Burkhard König, Pau Gorostiza, Karin Rustler
Publikováno v: Juelich Shared Electronic Resources
Recolector de Ciencia Abierta, RECOLECTA
PubMed Central
Diposit Digital de la Universitat de Barcelona
ZENODO
UnpayWall
ORCID
Microsoft Academic Graph
eNeuro
eNeuro 8(1), ENEURO.0294-20.2020 (2021). doi:10.1523/ENEURO.0294-20.2020
Dipòsit Digital de la UB
Universidad de Barcelona
Visual Abstract
Photopharmacology is a unique approach that through a combination of photochemistry methods and advanced life science techniques allows the study and control of specific biological processes, ranging from intracellular pathways t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85157fce2e1f37520dd1f809189e5c0b
http://europepmc.org/articles/PMC7877471
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5
Photocontrol of Endogenous Glycine Receptors In Vivo
Autor: Elvira Mukhametova, Alba Nin-Hill, Franck Peiretti, Burkhard König, Daniel Wutz, Piotr Bregestovski, Marat A. Mukhamedyarov, Xavier Rovira, Miquel Bosch, Daria Ponomareva, Carme Rovira, Pau Gorostiza, Karin Rustler, Galyna Maleeva, Antoni Bautista-Barrufet, Alexandre M. J. Gomila, Elena Petukhova, Mercedes Alfonso-Prieto
Publikováno v: Cell Chemical Biology
Cell Chemical Biology, Cell Press, 2020, 27 (11), pp.1425-1433.e7. ⟨10.1016/j.chembiol.2020.08.005⟩
Cell Chemical Biology, 2020, 27 (11), pp.1425-1433.e7. ⟨10.1016/j.chembiol.2020.08.005⟩
Cell chemical biology 27(11), 1425-1433.e7 (2020). doi:10.1016/j.chembiol.2020.08.005
International audience; Glycine receptors (GlyRs) are indispensable for maintaining excitatory/inhibitory balance in neuronal circuits that control reflexes and rhythmic motor behaviors. Here we have developed Glyght, a GlyR ligand controlled with li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed65a1a37c5f8c8a059ac5ec10c4b995
https://www.hal.inserm.fr/inserm-03032018/document
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6
Optical Control of GABA
Autor: Karin, Rustler, Galyna, Maleeva, Alexandre M J, Gomila, Pau, Gorostiza, Piotr, Bregestovski, Burkhard, König
Publikováno v: Chemistry (Weinheim an Der Bergstrasse, Germany)
Optogenetic and photopharmacological tools to manipulate neuronal inhibition have limited efficacy and reversibility. We report the design, synthesis, and biological evaluation of Fulgazepam, a fulgimide derivative of benzodiazepine that behaves as a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd1c05a23ac3bcb5a0d37725a40453ab
https://pubmed.ncbi.nlm.nih.gov/32307732
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7
Photocontrol of endogenous glycine receptors in vivo
Autor: Elvira Mukhametova, Alexandre M. J. Gomila, Karin Rustler, Piotr Bregestovski, Pau Gorostiza, Frank Peiretti, Miquel Bosch, Carme Rovira, Burkhard König, Alba Nin-Hill, Galyna Maleeva, Antoni Bautista-Barrufet, Xavier Rovira, Daniel Wutz, Marat A. Mukhamedyarov, Mercedes Alfonso-Prieto
Glycine receptors (GlyRs) are indispensable to maintain excitatory/inhibitory balance in neuronal circuits controlling reflex and rhythmic motor behaviors. Here we have developed Glyght, the first GlyR ligand controlled with light. It is selective ov
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cd45c9903cfa5a1aa7547cd47b9398
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9
Control of Cardiac Function in vivo with a Light-Regulated Drug
Autor: Carlo Matera, Alexandre M. J. Gomila, Ulrike Holzgrabe, Enrique Claro, Eduard Guasch, Fabio Riefolo, Pau Gorostiza, Michael Decker, Aida Garrido-Charles, Montserrat Batlle, Roser Masgrau, Luca Agnetta
Remote control of physiological functions with light offers the promise of unveiling their complex spatiotemporal dynamics in vivo, and enabling highly focalized therapeutic interventions with reduced systemic toxicity. Optogenetic methods have been
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5187e88e61803e404ffc09684150966
https://doi.org/10.26434/chemrxiv.7472174.v1
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10
A Photoswitchable Antimetabolite for Targeted Photoactivated Chemotherapy
Autor: Alexandre M. J. Gomila, Michela Libergoli, Pau Gorostiza, Concepció Soler, Carlo Matera, Núria Camarero
Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Journal of the American Chemical Society
The efficacy and tolerability of systemically administered anticancer agents are limited by their off-target effects. Precise spatiotemporal control over their cytotoxic activity would allow improving chemotherapy treatments, and light-regulated drug
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d618ad0168323a5a3f15ae92b288b7
http://hdl.handle.net/2445/126377
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