Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alexandre Loguinov"'
Autor:
Chris D. Vulpe, William E. Robinson, Alexandre Loguinov, Keegan S Krick, Bonnie J. Blalock, Helen C. Poynton
Publikováno v:
Environmental Science & Technology. 52:9419-9430
Transcriptomics, high-throughput assays, and adverse outcome pathways (AOP) are promising approaches applied to toxicity monitoring in the 21st century, but development of these methods is challenging for nonmodel organisms and emerging contaminants.
Autor:
Sarah Chan, Joshua M. Hicks, Helen C. Poynton, Alexandre Loguinov, Mark R. Viant, Kimberly L. Colson, Leona D. Scanlan, Chris D. Vulpe, Nadine S. Taylor, Candace Clark
Publikováno v:
Environmental Science & Technology. 45:3710-3717
Omic technologies offer unprecedented opportunities to better understand mode(s)-of-toxicity and downstream secondary effects by providing a holistic view of the molecular changes underlying physiological disruption. Crustacean hemolymph represents a
Publikováno v:
Environmental Science & Technology. 42:6257-6263
Genomic technologies show great potential for classifying disease states and toxicological impacts from exposure to chemicals into functional categories. In environmental monitoring, the ability to classify field samples and predict the pollutants pr
Autor:
Helen C. Poynton, Chris D. Vulpe, Julia R. Varshavsky, Sarah Chan, Edward J. Perkins, Alexandre Loguinov
Publikováno v:
Environmental Science & Technology. 42:6250-6256
Ecotoxicogenomic approaches to environmental monitoring provide holistic information, offer insight into modes of action, and help to assess the causal agents and potential toxicity of effluents beyond the traditional end points of death and reproduc
Autor:
Francesco Falciani, Quincy Teng, Erica R Lachenauer, Daniel Thomas Nowinski, Audrey Arai, Heather M. Stapleton, Alexandre Loguinov, Leona D. Scanlan, Xin Xin Lin, Philipp Antczak, Kathleen P. Dailey, Chris D. Vulpe, Nora K. Douglas, Jonah Kornbluh
Publikováno v:
ENVIRONMENTAL SCIENCE & TECHNOLOGY
The use of chemical flame-retardants (FR) in consumer products has steadily increased over the last 30 years. Toxicity data exist for legacy FRs such as pentabromodiphenyl ether (pentaBDE), but less is known about effects of new formulations. To addr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b35bbc0fa66d0577468e188edd24a13
https://europepmc.org/articles/PMC4835823/
https://europepmc.org/articles/PMC4835823/
Publikováno v:
Genes & Nutrition. 10
Hereditary hemochromatosis is an iron overload disorder most commonly caused by a defect in the HFE gene. While the genetic defect is highly prevalent, the majority of individuals do not develop clinically significant iron overload, suggesting the im
Autor:
Philipp Antczak, Robert B. Reed, Shaul Aloni, Francesco Falciani, Nadeeka Karunaratne, P. T. Luong, Daniel Thomas Nowinski, James F. Ranville, Chris D. Vulpe, Abderrahmane Tagmount, Alexandre Loguinov, Xin Xin Lin, Christopher P. Higgins, Leona D. Scanlan, Christine Tran, Benjamin Gilbert, Don Pham
Publikováno v:
ACS nano. 7(12)
Nanowires (NWs), high-aspect-ratio nanomaterials, are increasingly used in technological materials and consumer products and may have toxicological characteristics distinct from nanoparticles. We carried out a comprehensive evaluation of the physico-
Autor:
Christopher A. Impellitteri, Bonnie J. Blalock, H. Joel Allen, Alexandre Loguinov, Shekar Govindasmawy, Kim R. Rogers, Helen C. Poynton, J. Lee Heckman, James M. Lazorchak
Publikováno v:
Environmental sciencetechnology. 46(11)
Applications for silver nanomaterials in consumer products are rapidly expanding, creating an urgent need for toxicological examination of the exposure potential and ecological effects of silver nanoparticles (AgNPs). The integration of genomic techn
Autor:
Helen C. Poynton, Giorgio Cavigiolio, Elizabeth C. Theil, Owen Hughes, Sarah Chan, Alexandre Loguinov, Darren J. Bauer, Kelly Komachi, Julia R. Varshavsky, Edward J. Perkins, Chris D. Vulpe, Patricia S. Holman, Bonnie Chang
Publikováno v:
Environmental sciencetechnology. 41(3)
Toxicogenomics has provided innovative approaches to chemical screening, risk assessment, and predictive toxicology. If applied to ecotoxicology, genomics tools could greatly enhance the ability to understand the modes of toxicity in environmentally
Autor:
Martyn T. Smith, Alexandre Loguinov, Michele Fromowitz, Luoping Zhang, Matthew North, Kevin Shannon, Chris D. Vulpe, Joe Shuga
Publikováno v:
BMC Cancer
North, Matthew; Shuga, Joe; Fromowitz, Michele; Loguinov, Alexandre; Shannon, Kevin; Zhang, Luoping; et al.(2014). Modulation of Ras signaling alters the toxicity of hydroquinone, a benzene metabolite and component of cigarette smoke. BMC Cancer, 14(1), 6. doi: 10.1186/1471-2407-14-6. UC Berkeley: UC Berkeley Library. Retrieved from: http://www.escholarship.org/uc/item/1r05847c
North, Matthew; Shuga, Joe; Fromowitz, Michele; Loguinov, Alexandre; Shannon, Kevin; Zhang, Luoping; et al.(2014). Modulation of Ras signaling alters the toxicity of hydroquinone, a benzene metabolite and component of cigarette smoke. BMC Cancer, 14(1), 6. doi: 10.1186/1471-2407-14-6. UC Berkeley: UC Berkeley Library. Retrieved from: http://www.escholarship.org/uc/item/1r05847c
Background Benzene is an established human leukemogen, with a ubiquitous environmental presence leading to significant population exposure. In a genome-wide functional screen in the yeast Saccharomyces cerevisiae, inactivation of IRA2, a yeast orthol