CONTROL OF LOW-RESOLUTION SCANNING OF OVARIAN TUMOR STROMAL COMPARTMENT

Autor: Nicolas Elie, Alexandre Labiche, Jean-Jacques Michels, Paulette Herlin

Publikováno v: Image Analysis and Stereology, Vol 24, Iss 2, Pp 85-93 (2011)

The active search for markers of prognostic impact and therapeutic response is of crucial importance in oncology. The amount of stroma is a potential indicator with a significant impact on tumor growth. To solve the problems linked to tumor heterogen

Externí odkaz: https://doaj.org/article/f15c4bdf8c31413cb4a2c0ea353e3c1a

Front Cover: Parallel Screening with 14 C‐Labeled Carbon Dioxide: De‐risking the Staudinger‐Aza‐Wittig Reaction (Eur. J. Org. Chem. 30/2022)

Autor: Victor Babin, Antoine Sallustrau, Maxime Molins, Alexandre Labiche, Amélie Goudet, Frédéric Taran, Davide Audisio

Publikováno v: European Journal of Organic Chemistry. 2022

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3eb985d3472e32ca5f12c7fe1d45e3c
https://doi.org/10.1002/ejoc.202200864

A Photochemical Strategy for Carbon Isotope Exchange with CO 2

Autor: Antoine Sallustrau, Charles S. Elmore, Gianluca Destro, Alexandre Labiche, Victor Babin, Alex Talbot, Frédéric Taran, Antonio Del Vecchio, Davide Audisio

Publikováno v: ACS Catalysis
ACS Catalysis, 2021, 11 (5), pp.2968-2976. ⟨10.1021/acscatal.0c05344⟩
ACS Catalysis, American Chemical Society, 2021, 11 (5), pp.2968-2976. ⟨10.1021/acscatal.0c05344⟩

International audience; A photocatalytic approach for carbon isotope exchange is reported. Utilizing [ 13 C]CO2 and [ 14 C]CO2 as primary C1 sources, this protocol allows the insertion of the desired carbon isotope into phenyl acetic acids without th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f582564b6ec5f6a6b4ac95beaa83bb2
https://hal.science/hal-03176378

Identification of predictive factors of response to the BH3-mimetic molecule ABT-737: Anex vivoexperiment in human serous ovarian carcinoma

Autor: Audrey Emmanuelle Dugué, Laurent Poulain, Alexandre Labiche, Cécile Blanc-Fournier, Sandrine Martin, Edwige Abeilard, Soizic Dutoit, Bénédicte Clarisse, Monique N'Diaye, Florence Giffard, Mélanie Briand, Stephanie Lheureux, Hubert Crouet, Florence Joly, Jean-Michel Grellard

Publikováno v: International Journal of Cancer. 136:E340-E350

Ovarian cancers are addicted to Bcl-xL and Mcl-1, antiapoptotic members of the Bcl-2 family. Bcl-xL can be inhibited by the BH3-mimetic ABT-737. In vitro, ABT-737 can induce apoptosis of cancer cells, and its activity is potentiated by Mcl-1 inactiva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6a66602a19b108adad3dcd9a2af83ed
https://doi.org/10.1002/ijc.29104

Early evaluation of the effects of chemotherapy with longitudinal FDG small-animal PET in human testicular cancer xenografts: early flare response does not reflect refractory disease

Autor: Nicolas Aide, Alexandre Labiche, Alain Batalla, Laurent Poulain, Pascal Gauduchon, Françoise Montravers, Stéphane Allouche, Mélanie Briand, Soizic Dutoit, Aurélie Ngo-Van Do, Jean-Noël Talbot, Valérie Nataf

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 36:396-405

We aimed to evaluate the usefulness of FDG PET in the early prediction of the effects of chemotherapy on human testicular cancer xenografts.Nude rats bearing subcutaneous human embryonal carcinoma xenografts received either cisplatin (5 mg/kg) or sal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbd963168ed586e2f400c80332dba42
https://doi.org/10.1007/s00259-008-0984-x