Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alexandre Iarkov"'
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Parkinson’s disease (PD) is a neurodegenerative condition characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) in the midbrain resulting in progressive impairment in cognitive and motor abilities. The physi
Externí odkaz:
https://doaj.org/article/a9f3274ea83b4527911e23680aa885cf
Autor:
Patricia Oliveros-Matus, Nelson Perez-Urrutia, Nathalie Alvarez-Ricartes, Florencia Echeverria, George E. Barreto, James Elliott, Alexandre Iarkov, Valentina Echeverria
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Fear memory extinction (FE) is an important therapeutic goal for Posttraumatic stress disorder (PTSD). Cotinine facilitates FE in rodents, in part due to its inhibitory effect on the amygdala by the glutamatergic projections from the medial prefronta
Externí odkaz:
https://doaj.org/article/8ca9c7e62cf54cc3b99ec46435d53646
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Parkinson’s disease (PD) is the second-leading cause of dementia and is characterized by a progressive loss of dopaminergic neurons in the substantia nigra alongside the presence of intraneuronal α-synuclein-positive inclusions. Therapies to date
Externí odkaz:
https://doaj.org/article/e2145c71709f4bec988d93c78422d6be
Autor:
Nathalie Alvarez-Ricartes, Alexandre Iarkov, Valentina Echeverria, Cristhian Mendoza, Florencia Echeverria, Nelson Perez-Urrutia, Patricia Oliveros-Matus, George E. Barreto
Publikováno v:
Molecular Neurobiology. 55:7949-7960
Failure in fear extinction is one of the more troublesome characteristics of posttraumatic stress disorder (PTSD). Cotinine facilitates fear memory extinction and reduces depressive-like behavior when administered 24 h after fear conditioning in mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5cb4251592049c98de878e4dc7feef1
https://doi.org/10.1007/s12035-018-0916-0
https://doi.org/10.1007/s12035-018-0916-0
Autor:
George E. Barreto, Gjumrakch Aliev, Cristhian Mendoza, Valentina Echeverria, Alexandre Iarkov, Vadim V. Tarasov
Publikováno v:
Molecular Neurobiology. 55:6700-6711
Post-traumatic stress disorder (PTSD) is a mental disorder that may develop after exposure to exceptionally threatening or unescapable horrifying events. Actual therapies fail to alleviate the emotional suffering and cognitive impairment associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fabd51f11be69421e23dceb91cf1f049
https://doi.org/10.1007/s12035-018-0869-3
https://doi.org/10.1007/s12035-018-0869-3
Autor:
Patricia Oliveros-Matus, Florencia Echeverria, J. Alex Grizzell, Valentina. Echeverría, Alexandre Iarkov, Cristhian Mendoza, Nelson Perez-Urrutia, Nathalie Alvarez-Ricartes, George E. Barreto
Publikováno v:
Experimental neurology. 295
Posttraumatic stress disorder (PTSD), chronic psychological stress, and major depressive disorder have been found to be associated with a significant decrease in glial fibrillary acidic protein (GFAP) immunoreactivity in the hippocampus of rodents. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b546884989f674c5aa75f2f46be987c3
https://pubmed.ncbi.nlm.nih.gov/28625590
https://pubmed.ncbi.nlm.nih.gov/28625590
Autor:
J. Alex Grizzell, Alexandre Iarkov, Valentina Echeverria, Laura C. Charry, Adeeb Rohani, Michelle Mullins
Publikováno v:
Behavioral Neuroscience. 128:713-721
Cotinine, the predominant metabolite of nicotine, appears to act as an antidepressant. We have previously shown that cotinine reduced immobile postures in Porsolt's forced swim (FS) and tail suspension tests while preserving the synaptic density in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2fc0b5e3087c4830ab6de0b74439490
https://doi.org/10.1037/bne0000021
https://doi.org/10.1037/bne0000021
Publikováno v:
Cancer Chemotherapy And Pharmacology
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Most cancer patients treated with systemic adjuvant chemotherapy endure long-lasting side effects including decrease in concentration, forgetfulness and slower thinking, which are globally termed “chemobrain.” Cotinine, the main derivative of nic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdcc89779d3272587481299a5aab34e4
Publikováno v:
Journal of Neurophysiology. 104:1549-1565
The discharge properties of hindlimb motoneurons in ketamine–xylazine anesthetized rats were measured to assess contributions of persistent intrinsic currents to these characteristics and to determine their distribution in motoneuron pools. Most mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8342179fc2c0b90e0b8d17580e465278
https://doi.org/10.1152/jn.00379.2010
https://doi.org/10.1152/jn.00379.2010
Autor:
Nathalie Alvarez-Ricartes, Patricia Oliveros-Matus, Cristhian Mendoza, Nelson Perez-Urrutia, Florencia Echeverria, Alexandre Iarkov, George E. Barreto, Valentina Echeverria
Publikováno v:
Molecular Neurobiology
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c35170374fc294dfde5105ed464c8a
https://doi.org/10.1007/s12035-018-1095-8
https://doi.org/10.1007/s12035-018-1095-8