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pro vyhledávání: '"Alexandre Goumba"'
Autor:
Kyle Dickinson, Leah Hammond, Murielle Akpa, Lee Lee Chu, Caleb Tse Lalonde, Alexandre Goumba, Paul Goodyer
Publikováno v:
American journal of physiology. Renal physiology.
Mammalian nephrons arise from a population of nephron progenitor cells (NPCs) expressing the master transcription factor, WT1, which is crucial for NPC proliferation, migration, and differentiation. In humans, biallelic loss of WT1 precludes nephroge