Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alexandre G. Casanova"'
Autor:
Aurélie Richard, Jérémy Berthelet, Delphine Judith, Tamara Advedissian, Javier Espadas, Guillaume Jannot, Angélique Amo, Damarys Loew, Berangere Lombard, Alexandre G. Casanova, Nicolas Reynoird, Aurélien Roux, Clarisse Berlioz-Torrent, Arnaud Echard, Jonathan B. Weitzman, Souhila Medjkane
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Abscission is the final stage of cytokinesis, which cleaves the intercellular bridge (ICB) connecting two daughter cells. Abscission requires tight control of the recruitment and polymerization of the Endosomal Protein Complex Required for T
Externí odkaz:
https://doaj.org/article/6f91bd0d83724437a05ec67618c5988d
Autor:
Alexandre G. Casanova, Gael S. Roth, Simone Hausmann, Xiaoyin Lu, Ludivine J. M. Bischoff, Emilie M. Froeliger, Lucid Belmudes, Ekaterina Bourova-Flin, Natasha M. Flores, Ana Morales Benitez, Tourkian Chasan, Marcello Caporicci, Jessica Vayr, Sandrine Blanchet, Francesco Ielasi, Sophie Rousseaux, Pierre Hainaut, Or Gozani, Muriel Le Romancer, Yohann Couté, Andres Palencia, Pawel K. Mazur, Nicolas Reynoird
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/47e63f5c6a3744d6b26f87923884effe
Autor:
Alexandre G. Casanova, Gael S. Roth, Simone Hausmann, Xiaoyin Lu, Ludivine J. M. Bischoff, Emilie M. Froeliger, Lucid Belmudes, Ekaterina Bourova-Flin, Natasha M. Flores, Ana Morales Benitez, Tourkian Chasan, Marcello Caporicci, Jessica Vayr, Sandrine Blanchet, Francesco Ielasi, Sophie Rousseaux, Pierre Hainaut, Or Gozani, Muriel Le Romancer, Yohann Couté, Andres Palencia, Pawel K. Mazur, Nicolas Reynoird
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-22 (2024)
Abstract Malignant forms of breast cancer refractory to existing therapies remain a major unmet health issue, primarily due to metastatic spread. A better understanding of the mechanisms at play will provide better insights for alternative treatments
Externí odkaz:
https://doaj.org/article/077613e1385a431ba433f5e87d531e0f
Autor:
Nicolas Reynoird, Nima Mosammaparast, Pawel K. Mazur, Pierre Hainaut, Michiel Vermeulen, Yohann Couté, Pascal W.T.C. Jansen, Marianne Tardif, Rebecca Rodell, Jessica Vayr, Ana Morales Benitez, Florent Chuffart, Alexandre G. Casanova, Joshua R. Brickner, Ning Tsao, Tanveer Ahmad, Clement Oyeniran, Gael S. Roth, Simone Hausmann, Valentina Lukinović
Supplementary Table from SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032a5df391d5f4fa05c5afc7f2e1db25
https://doi.org/10.1158/2159-8290.22541404.v1
https://doi.org/10.1158/2159-8290.22541404.v1
Autor:
Nicolas Reynoird, Nima Mosammaparast, Pawel K. Mazur, Pierre Hainaut, Michiel Vermeulen, Yohann Couté, Pascal W.T.C. Jansen, Marianne Tardif, Rebecca Rodell, Jessica Vayr, Ana Morales Benitez, Florent Chuffart, Alexandre G. Casanova, Joshua R. Brickner, Ning Tsao, Tanveer Ahmad, Clement Oyeniran, Gael S. Roth, Simone Hausmann, Valentina Lukinović
Small cell lung cancer (SCLC) is the most fatal form of lung cancer, with dismal survival, limited therapeutic options, and rapid development of chemoresistance. We identified the lysine methyltransferase SMYD3 as a major regulator of SCLC sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7aff3a4b13eb09415758e2513af039
https://doi.org/10.1158/2159-8290.c.6549634.v1
https://doi.org/10.1158/2159-8290.c.6549634.v1
Autor:
Nicolas Reynoird, Nima Mosammaparast, Pawel K. Mazur, Pierre Hainaut, Michiel Vermeulen, Yohann Couté, Pascal W.T.C. Jansen, Marianne Tardif, Rebecca Rodell, Jessica Vayr, Ana Morales Benitez, Florent Chuffart, Alexandre G. Casanova, Joshua R. Brickner, Ning Tsao, Tanveer Ahmad, Clement Oyeniran, Gael S. Roth, Simone Hausmann, Valentina Lukinović
Supplementary Data from SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01500e10207400a070376439f471923d
https://doi.org/10.1158/2159-8290.22541428.v1
https://doi.org/10.1158/2159-8290.22541428.v1
Autor:
Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird
Publikováno v:
Cancer Discovery
Cancer Discovery, In press, ⟨10.1158/2159-8290.CD-21-0205⟩
Cancer Discovery, 12, 2158-2179
Cancer Discovery, 12, 9, pp. 2158-2179
Cancer Discovery, In press, ⟨10.1158/2159-8290.CD-21-0205⟩
Cancer Discovery, 12, 2158-2179
Cancer Discovery, 12, 9, pp. 2158-2179
Small cell lung cancer (SCLC) is the most fatal form of lung cancer, with dismal survival, limited therapeutic options, and rapid development of chemoresistance. We identified the lysine methyltransferase SMYD3 as a major regulator of SCLC sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a6f369ad5cbcb85ed2d339d7aa9050
https://cnrs.hal.science/hal-03759864/document
https://cnrs.hal.science/hal-03759864/document
Autor:
Alexandre G. Casanova, Li-Sheng Zhang, Ning Tsao, Brittany A. Townley, Nima Mosammaparast, Joshua R. Brickner, Chuan He, John A. Tainer, Rebecca Rodell, Tanveer Ahmad, Matthew D. Wood, Hua Sun, Jennifer M. Soll, Nicolas Reynoird, Clement Oyeniran, Alessandro Vindigni, Adit Ganguly, Albino Bacolla, Valentina Lukinović
Publikováno v:
Mol Cell
Molecular Cell
Molecular Cell, 2021, 81 (20), pp.4228-4242.e8. ⟨10.1016/j.molcel.2021.09.024⟩
Molecular Cell
Molecular Cell, 2021, 81 (20), pp.4228-4242.e8. ⟨10.1016/j.molcel.2021.09.024⟩
International audience; Summary Central to genotoxic responses is their ability to sense highly specific signals to activate the appropriate repair response. We previously reported that the activation of the ASCC-ALKBH3 repair pathway is exquisitely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22341f9c122e9653e82bea7080278c0
https://europepmc.org/articles/PMC8931856/
https://europepmc.org/articles/PMC8931856/
Publikováno v:
Current Protein & Peptide Science
Current Protein & Peptide Science, Bentham Science, 2020, 21 (7), pp.655-674. ⟨10.2174/1871527319666200102101608⟩
Current Protein and Peptide Science
Current Protein and Peptide Science, 2020, 21 (7), pp.655-674. ⟨10.2174/1871527319666200102101608⟩
Current Protein & Peptide Science, Bentham Science, 2020, 21 (7), pp.655-674. ⟨10.2174/1871527319666200102101608⟩
Current Protein and Peptide Science
Current Protein and Peptide Science, 2020, 21 (7), pp.655-674. ⟨10.2174/1871527319666200102101608⟩
Protein lysine methylation is a functionally diverse post-translational modification involved in various major cellular processes. Lysine methylation can modulate proteins activity, stability, localization, and/or interaction, resulting in specific d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1c7a233e9f82ae067e0179e143965e
https://hal.archives-ouvertes.fr/hal-02989776
https://hal.archives-ouvertes.fr/hal-02989776
Autor:
Rebecca Rodell, Nima Mosammaparast, Ning Tsao, Nicolas Reynoird, Li-Sheng Zhang, Alexandre G. Casanova, Valentina Lukinović, Joshua R. Brickner, Jennifer M. Soll, Adit Ganguly, Chuan He, Clement Oyeniran, John A. Tainer, Albino Bacolla
SummaryA critical question in genome stability is the nature of the chemical damage responsible for repair activation. We previously reported a novel pathway specifically activated during alkylation damage in human cells, where the E3 ubiquitin ligas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867951cfd90be837ec436deaf9848cf3
https://doi.org/10.1101/2020.08.28.271874
https://doi.org/10.1101/2020.08.28.271874