Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Alexandre F. R. Stewart"'
Autor:
Ragnar O. Vilmundarson, Niloufar Heydarikhorneh, An Duong, Tiffany Ho, Kianoosh Keyhanian, Fariborz Soheili, Hsiao-Huei Chen, Alexandre F. R. Stewart
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interferon regulatory factor 2 binding protein 2 (Irf2bp2), a co-repressor of Irf2, is required for fetal hepatic erythropoiesis through the expansion of erythromyeloid progenitors. Mice with germline ablation of the entire Irf2bp2 transcript produce
Externí odkaz:
https://doaj.org/article/e03ef4bb8eaa4ca5bdf0ca3f13313cc3
Autor:
Li Zhang, Zhaohong Qin, Konrad M. Ricke, Shelly A. Cruz, Alexandre F. R. Stewart, Hsiao-Huei Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
LMO4 has been linked genetically to autism spectrum disorder and intellectual disability. Here, the authors investigate a role of LMO4 in parvalbumin neurons and, specifically, the regulation of dorsal ACC inhibitory circuits.
Externí odkaz:
https://doaj.org/article/fe86987c92da4b6d89472524a3eac3c1
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Interferon regulatory factor 2 binding protein 2 (IRF2BP2) suppresses the innate inflammatory response of macrophages. A 9-nucleotide deletion (rs3045215) in the 3′ untranslated region (3′-UTR) of human IRF2BP2 mRNA confers risk of coronary arter
Externí odkaz:
https://doaj.org/article/4b48673f8ad046c6ab62130845a05013
Publikováno v:
Viruses, Vol 14, Iss 3, p 559 (2022)
Human breast cancer incidence varies by geographic location. More than 20 years ago, we proposed that zoonotic transmission of the mouse mammary tumor virus (MMTV) from the western European house mouse, Mus musculus domesticus, might account for the
Externí odkaz:
https://doaj.org/article/1b759d1a71f54cd5b4e828db785d66ea
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 2, Pp 252-256 (2018)
Ischemic brain injury triggers neuronal cell death by apoptosis via caspase activation and by necroptosis through activation of the receptor-interacting protein kinases (RIPK) associated with the tumor necrosis factor-alpha (TNF-α)/death receptor. R
Externí odkaz:
https://doaj.org/article/0da94da1294a410a957354af85c4305a
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 12, Pp 2245-2246 (2020)
Externí odkaz:
https://doaj.org/article/349352d1f3ae43d9a89f6f5723116cd5
Autor:
Jaana A. Hartiala, W. H. Wilson Tang, Zeneng Wang, Amanda L. Crow, Alexandre F. R. Stewart, Robert Roberts, Ruth McPherson, Jeanette Erdmann, Christina Willenborg, Stanley L. Hazen, Hooman Allayee
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Dietary choline metabolites, such as trimethylamine N-oxide and betaine, have been associated with coronary artery disease (CAD). Here, Hartiala et al. identify two genetic loci for betaine levels on chromosomes 2q34 and 5q14.1 and find that the 2q34
Externí odkaz:
https://doaj.org/article/a43466011e9a467bab3474f2025c21a0
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 11, Pp 1762-1764 (2017)
Ischemic brain injury triggers an inflammatory response. This response is necessary to clear damaged brain tissue but can also exacerbate brain injury. Microglia are the innate immune cells of the brain that execute this critical function. In healthy
Externí odkaz:
https://doaj.org/article/e076998bbfc94194ac6fd6ee2fb7f1f0
Autor:
Shelly A. Cruz, Aswin Hari, Zhaohong Qin, Pascal Couture, Hua Huang, Diane C. Lagace, Alexandre F. R. Stewart, Hsiao-Huei Chen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Ischemic stroke causes neuronal cell death and triggers a cascade of inflammatory signals that contribute to secondary brain damage. Microglia, the brain-resident macrophages that remove dead neurons, play a critical role in the brain’s response to
Externí odkaz:
https://doaj.org/article/d80146b09b2d4f23a6103e0b821f1115
Autor:
Marc-Phillip Hitz, Louis-Philippe Lemieux-Perreault, Christian Marshall, Yassamin Feroz-Zada, Robbie Davies, Shi Wei Yang, Anath Christopher Lionel, Guylaine D'Amours, Emmanuelle Lemyre, Rebecca Cullum, Jean-Luc Bigras, Maryse Thibeault, Philippe Chetaille, Alexandre Montpetit, Paul Khairy, Bert Overduin, Sabine Klaassen, Pamela Hoodless, Philip Awadalla, Julie Hussin, Youssef Idaghdour, Mona Nemer, Alexandre F. R. Stewart, Cornelius Boerkoel, Stephen W. Scherer, Andrea Richter, Marie-Pierre Dubé, Gregor Andelfinger
Publikováno v:
PLoS Genetics, Vol 9, Iss 3 (2013)
Externí odkaz:
https://doaj.org/article/5fedba472a7542699aadf367acb12b14