Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Alexandre E. Escargueil"'
Autor:
Ambre Dezaire, Christophe H. Marchand, Marine Vallet, Nathalie Ferrand, Soraya Chaouch, Elisabeth Mouray, Annette K. Larsen, Michèle Sabbah, Stéphane D. Lemaire, Soizic Prado, Alexandre E. Escargueil
Publikováno v:
Marine Drugs, Vol 18, Iss 4, p 191 (2020)
High-throughput screening assays have been designed to identify compounds capable of inhibiting phenotypes involved in cancer aggressiveness. However, most studies used commercially available chemical libraries. This prompted us to explore natural pr
Externí odkaz:
https://doaj.org/article/253b1a75689c45a5ada47662805d221b
Autor:
Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares
Supplementary Figure 2 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6143b96fa93dd17df198217419a851cb
https://doi.org/10.1158/1535-7163.22497007
https://doi.org/10.1158/1535-7163.22497007
Autor:
Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares
Supplementary Figure 1 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a19479773794b88b98afe698935106f
https://doi.org/10.1158/1535-7163.22497010
https://doi.org/10.1158/1535-7163.22497010
Autor:
Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares
Supplementary Figure 3 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568fdb909bd7c8e5b8b759927c62554f
https://doi.org/10.1158/1535-7163.22497004
https://doi.org/10.1158/1535-7163.22497004
Autor:
Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares
Supplementary Figure 4 from Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a2f8057a9be951437d8ffe613851a7
https://doi.org/10.1158/1535-7163.22497001
https://doi.org/10.1158/1535-7163.22497001
Autor:
Annette K. Larsen, Alexandre E. Escargueil, João A.P. Henriques, Carlos M. Galmarini, Alain Sarasin, Djamila Ouaret, Virginie Poindessous, Céline J. Rocca, Miriana S. Machado, Daniele G. Soares
PM01183 is a novel marine-derived covalent DNA binder in clinical development. PM01183 is structurally similar to trabectedin (yondelis, ecteinascidin-743) except for the C subunit, and this modification is accompanied by different pharmacokinetics i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd29afa3bcc5f8ff9581b8efc6beead0
https://doi.org/10.1158/1535-7163.c.6535465
https://doi.org/10.1158/1535-7163.c.6535465
Autor:
Annette K. Larsen, Aimery de Gramont, Thierry André, Christophe Tournigand, Benoist Chibaudel, Ariel Savina, Alexandre E. Escargueil, Michèle Sabbah, Nathalie Ferrand, Anaïs Bouygues, Paul Mésange
Influence of bevacizumab (Beva), erlotinib (Erlo) and their combination (Beva + Erlo) on the tumor growth of CRC xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112e1e45b02ce7b61fd6dc9c56691276
https://doi.org/10.1158/1078-0432.22470387.v1
https://doi.org/10.1158/1078-0432.22470387.v1
Autor:
Annette K. Larsen, Aimery de Gramont, Thierry André, Christophe Tournigand, Benoist Chibaudel, Ariel Savina, Alexandre E. Escargueil, Michèle Sabbah, Nathalie Ferrand, Anaïs Bouygues, Paul Mésange
Purpose: There is extensive cross-talk between VEGF- and EGFR-pathway signaling in colorectal cancer. However, combinations of VEGF- and EGFR-targeted monoclonal antibodies (mAb) show disappointing activity, in particular for patients with mutant RAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304331454fe79dacd17dc807a13af280
https://doi.org/10.1158/1078-0432.c.6527547
https://doi.org/10.1158/1078-0432.c.6527547
Autor:
Annette K. Larsen, Aimery de Gramont, Thierry André, Christophe Tournigand, Benoist Chibaudel, Ariel Savina, Alexandre E. Escargueil, Michèle Sabbah, Nathalie Ferrand, Anaïs Bouygues, Paul Mésange
The influence of 72 hrs exposure to vehicle, erlotinib (Erlo, 10 µM) or cetuximab (Cetux, 1 µg/mL) on the viability of the indicated CRC cell lines as measured by the TUNEL assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4fa46acac0e42ecf0ef41c37943fa8
https://doi.org/10.1158/1078-0432.22470381
https://doi.org/10.1158/1078-0432.22470381
Autor:
Annette K. Larsen, Aimery de Gramont, Thierry André, Christophe Tournigand, Benoist Chibaudel, Ariel Savina, Alexandre E. Escargueil, Michèle Sabbah, Nathalie Ferrand, Anaïs Bouygues, Paul Mésange
The expression of total VEGFR1 and VEGFR2 was determined by ELISA analysis of tumor extracts (3 tumors per treatment).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2c26d91a3c2c7b702f1084d058a250
https://doi.org/10.1158/1078-0432.22470384
https://doi.org/10.1158/1078-0432.22470384