Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Alexandre Dufour"'
Autor:
Alexandre Dufour, Lucie Essayan, Céline Thomann, Emma Petiot, Isabelle Gay, Magali Barbaroux, Christophe Marquette
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The future of organ and tissue biofabrication strongly relies on 3D bioprinting technologies. However, maintaining sterility remains a critical issue regardless of the technology used. This challenge becomes even more pronounced when the vol
Externí odkaz:
https://doaj.org/article/ab2983f197944a74aae92d9700c6debd
Autor:
Alexandre Dufour, Jérôme E. Lafont, Marie Buffier, Michaël Verset, Angéline Cohendet, Hugues Contamin, Joachim Confais, Sharanya Sankar, Marc Rioult, Emeline Perrier-Groult, Frédéric Mallein-Gerin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Articular cartilage is built by chondrocytes which become less active with age. This declining function of the chondrocytes, together with the avascular nature of the cartilage, impedes the spontaneous healing of chondral injuries. These les
Externí odkaz:
https://doaj.org/article/b9869d987c60479f81ee8759550420fe
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 216 (2022)
Articular cartilage (AC) possesses a limited healing potential, meaning that untreated focal joint defects typically progress, leading to the development of degenerative diseases such as osteoarthritis. Several clinical strategies exist that aim to r
Externí odkaz:
https://doaj.org/article/c2afad2a4fff4f569be6e2df328cd483
Autor:
Thibault Lagache, Alexandre Grassart, Stéphane Dallongeville, Orestis Faklaris, Nathalie Sauvonnet, Alexandre Dufour, Lydia Danglot, Jean-Christophe Olivo-Marin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Elucidating molecular organisation requires precise localisation and analysis. Here the authors develop SODA software for automatic and quantitative mapping of statistically coupled molecules, and use it to unravel spatial organisation of thousands o
Externí odkaz:
https://doaj.org/article/c72243110cc94c5f96e08005bd345ee6
Publikováno v:
Applied Sciences, Vol 11, Iss 19, p 8923 (2021)
Articular cartilage has limited potential for self-repair, and cell-based strategies combining scaffolds and chondrocytes are currently used to treat cartilage injuries. However, achieving a satisfying level of cell redifferentiation following expans
Externí odkaz:
https://doaj.org/article/9c0d868128254d1db5d8a3f589ff7a09
Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth
Autor:
Chiara V. Ragni, Nicolas Diguet, Jean-François Le Garrec, Marta Novotova, Tatiana P. Resende, Sorin Pop, Nicolas Charon, Laurent Guillemot, Lisa Kitasato, Caroline Badouel, Alexandre Dufour, Jean-Christophe Olivo-Marin, Alain Trouvé, Helen McNeill, Sigolène M Meilhac
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Growth of the mammalian heart is controlled by Hippo signalling but how this is regulated is unclear. Here, the authors show that Fat4 (an atypical cadherin) acts upstream of Hippo signalling and Fat4 mutant mice have thicker myocardium, which is med
Externí odkaz:
https://doaj.org/article/e8f4fd524d4c427fa1e8c9b37e7353f2
Autor:
Anne-Laure Durand, Alexandre Dufour, Elisabeth Aubert-Foucher, Christine Oger-Desfeux, Marielle Pasdeloup, Sebastien Lustig, Elvire Servien, Gualter Vaz, Emeline Perrier-Groult, Frederic Mallein-Gerin, Jerome E. Lafont
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6322 (2020)
Osteoarthritis (OA) is a degenerative disease of the joints which is associated with an impaired production of the cartilage matrix by the chondrocytes. Here, we investigated the role of Lysine-Specific Demethylase-1 (LSD1), a chromatin remodeling en
Externí odkaz:
https://doaj.org/article/e8e8c4b21cbb466881f959eb5d96acd3
Autor:
Debora B Petropolis, Daniela M Faust, Matthieu Tolle, Lise Rivière, Tanguy Valentin, Christine Neuveut, Nora Hernandez-Cuevas, Alexandre Dufour, Jean-Christophe Olivo-Marin, Nancy Guillen
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148667 (2016)
Human liver infection is a major cause of death worldwide, but fundamental studies on infectious diseases affecting humans have been hampered by the lack of robust experimental models that accurately reproduce pathogen-host interactions in an environ
Externí odkaz:
https://doaj.org/article/d7e5a1b5f6274f158834a7bef6b101e3
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99197 (2014)
Chlamydiae are obligate intracellular bacteria. These pathogens develop inside host cells through a biphasic cycle alternating between two morphologically distinct forms, the infectious elementary body and the replicative reticulate body. Recently, C
Externí odkaz:
https://doaj.org/article/a3fb6ec6bfef440fa0a36642261c91b2
Autor:
Laetitia Travier, Stéphanie Guadagnini, Edith Gouin, Alexandre Dufour, Viviane Chenal-Francisque, Pascale Cossart, Jean-Christophe Olivo-Marin, Jean-Marc Ghigo, Olivier Disson, Marc Lecuit
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003131 (2013)
Listeria monocytogenes (Lm) is a ubiquitous bacterium able to survive and thrive within the environment and readily colonizes a wide range of substrates, often as a biofilm. It is also a facultative intracellular pathogen, which actively invades dive
Externí odkaz:
https://doaj.org/article/aa1a86c8e0a74af0a68e1874ffb91487