Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alexandre Domingues Barbosa"'
Autor:
Isaura Isabelle Fonseca Gomes da Silva, Denise de Queiroga Nascimento, Alexandre Domingues Barbosa, Fabricio Oliveira Souto, Maria de Mascena Diniz Maia, Sergio Crovella, Paulo Roberto Eleuterio de Souza, Paula Sandrin-Garcia
Publikováno v:
Genetics and Molecular Biology, Vol 47, Iss 2 (2024)
Abstract We predicted miRNAs with regulatory impact on NFKB1 and TRAF6 gene expression and selected the miR-194-5p, miR-124-3p, miR-9-5p, and miR-340-5p and their target genes for expression analyses on CD14+ monocytes from rheumatoid arthritis (RA)
Externí odkaz:
https://doaj.org/article/566c607634db470993a290283a310f08
Autor:
Werbson Lima Guaraná, Camilla Albertina Dantas Lima, Alexandre Domingues Barbosa, Sergio Crovella, Paula Sandrin-Garcia
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5623 (2024)
Aminobisphosphonates (NBPs) are the first-choice medication for osteoporosis (OP); NBP treatment aims at increasing bone mineral density (BMD) by inhibiting the activity of farnesyl diphosphate synthase (FDPS) enzyme in osteoclasts. Despite its effic
Externí odkaz:
https://doaj.org/article/56868c4c6f3e4cd287eda3715c07455d
Autor:
Catarina Addobbati Jordão Cavalcanti, Vanessa Germoglio, Jaqueline de Azevêdo Silva, Nadine Glesse, Priscila Vianna, Giovana Cechim, Odirlei Andre Monticielo, Ricardo Machado Xavier, João Carlos Tavares Brenol, Claiton Viegas Brenol, Thiago Sotero Fragoso, Alexandre Domingues Barbosa, Ângela Luiza Branco Pinto Duarte, Renê Donizeti Ribeiro Oliveira, Paulo Louzada-Júnior, Eduardo Antônio Donadi, José Artur Bogo Chies, Sergio Crovella, Paula Sandrin-Garcia
Publikováno v:
Autoimmunity, Vol 53, Iss 2, Pp 65-70 (2020)
The aim of the present study was to evaluate the impact of SEMA4A genetic variants on expression of sema4A protein and its relation to autoimmunity development in Systemic Lupus Erythematosus and Rheumatoid Arthritis patients. A total of 541 SLE pati
Externí odkaz:
https://doaj.org/article/b710504c7eb64163b8ae7fe6126d6183
Autor:
Emmanuelle Tenório Albuquerque Madruga Godoi, Alexandre Domingues Barbosa, Juannicelle Tenório Albuquerque Madruga Godoi, Mariana Atanásio Morais Ramos, Jocelene Tenório Albuquerque Madruga Godoi, Silvio Romero de Barros Marques, Ângela Luzia Branco Pinto Duarte
Publikováno v:
Jornal Vascular Brasileiro, Vol 8, Iss 1, Pp 65-76 (2009)
Este artigo tem como objetivo revisar os aspectos descritos na literatura sobre o acometimento da macrovasculatura na esclerose sistêmica e avaliar a ocorrência e distribuição das alterações macrovasculares nos pacientes com esclerose sistêmic
Externí odkaz:
https://doaj.org/article/56a00c2145f0436195c1896faf14e9cb
Autor:
Emmanuelle Tenório Albuquerque Madruga Godoi, Alexandre Domingues Barbosa, Juannicelle Tenório Albuquerque Madruga Godoi, Mariana Atanásio Morais Ramos, Jocelene Tenório Albuquerque Madruga Godoi, Sílvio Romero de Barros Marques, Ângela Luzia Branco Pinto Duarte
Publikováno v:
Revista Brasileira de Reumatologia, Vol 48, Iss 2, Pp 86-93 (2008)
OBJETIVO: Avaliar a ocorrência e a distribuição das alterações macrovasculares em uma população com esclerose sistêmica (ES) por meio da ultra-sonografia Doppler (USG Doppler) e do índice tornozelo-braço (ITB). Foi investigada a associaçã
Externí odkaz:
https://doaj.org/article/af17de7a2a784fdbbdcf3a0aa574bd17
Autor:
Jaqueline de Azevêdo Silva, Camilla Albertina Dantas de Lima, Werbson Lima Guaraná, Alexandre Domingues Barbosa, Thiago Sotero Fragoso, Ângela Luzia Branco Pinto Duarte, Sergio Crovella, Paula Sandrin‐Garcia
Publikováno v:
International Journal of Immunogenetics. 50:75-81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f47421f8201c2d02c9dc8967fac05b
https://doi.org/10.1111/iji.12613
https://doi.org/10.1111/iji.12613
Autor:
Jaqueline De Azevêdo Silva, Suelen Cristina Lima, Thiago Sotero Fragoso, Catarina Addobbati Jordão Cavalcanti, Alexandre Domingues Barbosa, Maria Eduarda de Albuquerque Borborema, Thays Maria Costa Lucena, Angela Luzia Branco Pinto Duarte, Sergio Crovella, Paula Sandrin‐Garcia
Publikováno v:
International Journal of Immunogenetics. 49:181-192
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disorder that displays an important genetic background. Vitamin D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a351a55730fad565e5af195955e62395
https://doi.org/10.1111/iji.12576
https://doi.org/10.1111/iji.12576
Autor:
Werbson Lima Guaraná, Camilla Albertina Dantas Lima, Alexandre Domingues Barbosa, Sergio Crovella, Paula Sandrin-Garcia
Publikováno v:
Genes; Volume 13; Issue 12; Pages: 2271
The immune system plays a critical role in bone homeostasis and, consequently, in the pathophysiology of postmenopausal osteoporosis (OP) since estrogen deficiency induces the inflammasome and increases production of pro-inflammatory cytokines, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3eeda3a91b4364c79e03ba3ffc6d19
Autor:
Fabrício Oliveira Souto, Sergio Crovella, Isaura Isabelle Fonseca Gomes da Silva, Paula Sandrin-Garcia, Maria de Mascena Diniz Maia, Alexandre Domingues Barbosa, Paulo Roberto Eleutério de Souza
Rheumatoid arthritis (RA) is a well-known chronic inflammatory disorder. Two molecular players act in the inflammation balance of the disease: MyD88 (Myeloid differentiation primary response 88) is related to TLR (Toll-like receptors) response and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc92a37a132fd1c9b4435d5ac5fde5e1
https://hdl.handle.net/10576/25917
https://hdl.handle.net/10576/25917
Autor:
Sergio Crovella, Jaqueline de Azevêdo Silva, Will de Barros Pita, Alexandre Domingues Barbosa, Camilla Albertina Dantas de Lima, Suelen Cristina de Lima, Paula Sandrin-Garcia
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Osteoporosis (OP) is a multifactorial disease influenced by genetic factors in more than half of the cases. In spite of the efforts to clarify the relationship among genetic factors and susceptibility to develop OP, many genetic associations need to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456a18d43a3e1879d3b97463fa909611
http://link.springer.com/article/10.1038/s41598-019-52612-9
http://link.springer.com/article/10.1038/s41598-019-52612-9